Search results for "Adhesion"

showing 10 items of 1165 documents

Differentiative pathway activated by 3-aminobenzamide in human osteosarcoma MG-63 cells involves FAK and PAK activities.

2006

PARP inhibitorosteosarcomafocal adhesions
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The impact of growth history and flagellation on the adhesion of variousListeria monocytogenesstrains to polystyrene

2009

International audience; The contribution of growth history and flagella to adhesion of Listeria monocytogenes was analysed. An in-frame deletion on the flagellin encoding gene (flaA) was performed in L. monocytogenes EGD-e to compare its adhesion ability with the parental strain, after cultivation at various pH values and temperatures. The pH, as well as the temperature, affected the adhesion of L. monocytogenes EGD-e. In addition, the adhesion of L. monocytogenes EGD-e was reduced in energy-depressed cells. Conversely, the physicochemical bacterial surface characteristics affected by growth history did not influence the adhesion. Adhesion variations observed among environmental and clinica…

PHGram-positive bacteriaImmunologyMutantFlagellummedicine.disease_causeApplied Microbiology and BiotechnologyMicrobiologyBacterial AdhesionMicrobiology03 medical and health sciencesADHERENCEListeria monocytogenesGeneticsmedicineHumansListeriosisMolecular Biology030304 developmental biology2. Zero hunger0303 health sciencesbiologyStrain (chemistry)LISTERIA MONOCYTOGENES030306 microbiologyTemperatureFLAGELLINEGeneral MedicineAdhesionHydrogen-Ion Concentrationbiology.organism_classificationCulture Media[SDV.MP]Life Sciences [q-bio]/Microbiology and ParasitologyFlagella13. Climate actionbiology.proteinPolystyrenesFlagellinBacteriaFlagellinCanadian Journal of Microbiology
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Behavior of Human Osteoblast Cells Cultured on Titanium Discs in Relation to Surface Roughness and Presence of Melatonin

2017

The aim of this work was to observe the behavior of osteoblast cells cultured in vitro on titanium discs in relation to disc surface roughness and the addition of melatonin to the culture medium. MG63 osteoblast cells were cultivated on 120 Grade 5 Ti divided into three groups: Group E, treated with dual acid etch; Group EP, treated with dual acid etch and calcium phosphate; and Group M, machined. Surface roughness was examined under a laser scanning confocal microscope (CLSM) and scanning electron microscopy (SEM). The proliferation and morphology of cells were determined under fluorescence microscopy and SEM. Messenger ribonucleic acid (mRNA) of different genes related to osteoblastic dif…

PHEXSurface PropertiesproliferationmRNAConfocalchemistry.chemical_elementmelatoninosteoblasts; titanium; roughness; melatonin; proliferation; differentiation; mRNA; PHEX; dental implantsCalciumArticleCatalysisOsseointegrationCell LineInorganic ChemistryMelatonin03 medical and health sciences0302 clinical medicinedental implantsCell AdhesionmedicineFluorescence microscopeHumansRNA MessengerPhysical and Theoretical ChemistryMolecular BiologySpectroscopyCell ProliferationroughnessTitaniumMicroscopy ConfocalOsteoblastsCell growthOrganic ChemistryCell DifferentiationOsteoblastdifferentiation030206 dentistryGeneral MedicineAnatomyMolecular biologyIn vitroComputer Science Applicationsmedicine.anatomical_structurechemistryMicroscopy Electron Scanning030217 neurology & neurosurgerymedicine.drugInternational Journal of Molecular Sciences
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Fiber Post Removal: Comparative Study Using a New Post Concept

2009

Objectives: To evaluate the time required to remove endodontic posts made of quartz and glass fibers, and compare them to a new glass fiber post designed for easy removal on the basis of efficiency and tooth damages. Methods: 40 human single-rooted teeth were treated endodontically and randomly assigned to four fiber posts groups: 1) was restored with Premier#90 (Innotech); 2) with DT#2 Lightpost (Dentsply); 3) with Unicore#3 (Ultradent); 4) with a special, soft-cored “S” glass fiber post ER-Prosthetic#3 (Overfibers). An impression of the canal was taken prior post cementation. The posts were luted with Panavia F and adhesive (Kuraray). All the specimens were mounted in a dental simulation …

POST REMOVALCOMPOSITESFIBER POSTLUTING CEMENTSAdhesion Fiber-reinforced composites Root Cements CompositesENDODONTIC RE-TREATMENT
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New scenarios for neuronal structural plasticity in non-neurogenic brain parenchyma: the case of cortical layer II immature neurons

2011

The mammalian central nervous system, due to its interaction with the environment, must be endowed with plasticity. Conversely, the nervous tissue must be substantially static to ensure connectional invariability. Structural plasticity can be viewed as a compromise between these requirements. In adult mammals, brain structural plasticity is strongly reduced with respect to other animal groups in the phylogenetic tree. It persists under different forms, which mainly consist of remodeling of neuronal shape and connectivity, and, to a lesser extent, the production of new neurons. Adult neurogenesis is mainly restricted within two neurogenic niches, yet some gliogenic and neurogenic processes a…

PSA-NCAMNeurogenesisPopulationDoublecortinAdult neurogenesisImmature neuronNeural Stem CellsSpecies SpecificityNeuroplasticityAnimalsHumansRegenerationeducationCerebral CortexMammalsNeuronsStructural plasticityeducation.field_of_studyNeuronal PlasticitybiologyGeneral NeuroscienceNeurogenesisNeural stem cellDoublecortinOrgan SpecificitySynaptic plasticitybiology.proteinNeural cell adhesion moleculeTBR1NeurogliaNeuroscienceAdult neurogenesis; Structural plasticity; PSA-NCAM; Doublecortin; Immature neuron; Regeneration
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Increased Vascularity in Cervicovaginal Mucosa with Schistosoma haematobium Infection

2011

Background Close to 800 million people in the world are at risk of schistosomiasis, 85 per cent of whom live in Africa. Recent studies have indicated that female genital schistosomiasis might increase the risk of human immunodeficiency virus (HIV) infection. The aim of this study is to quantify and analyse the characteristics of the vasculature surrounding Schistosoma haematobium ova in the female genital mucosa. Methodology/Principal Findings Cervicovaginal biopsies with S. haematobium ova (n = 20) and control biopsies (n = 69) were stained with immunohistochemical blood vessel markers CD31 and von Willebrand Factor (vWF), which stain endothelial cells in capillary buds and established blo…

PathologyAnatomy and PhysiologyBiopsyVDP::Medical disciplines: 700::Clinical medical disciplines: 750::Tropical medicine: 761Gynecologic InfectionsPathogenesisCervix UteriCardiovascularSchistosomiasis haematobiaVascularitySchistosomiasisSchistosoma haematobiumMicroscopyNeovascularization PathologicHistocytochemistrylcsh:Public aspects of medicineMucous membraneMiddle AgedImmunohistochemistryPlatelet Endothelial Cell Adhesion Molecule-1Infectious Diseasesmedicine.anatomical_structureMedical MicrobiologyVaginaSchistosoma haematobiumVaginaNeglected tropical diseasesMedicineFemalemedicine.symptomImmunohistochemical AnalysisResearch ArticleNeglected Tropical DiseasesAdultmedicine.medical_specialtylcsh:Arctic medicine. Tropical medicineHistologyAdolescentlcsh:RC955-962ImmunologySchistosomiasisBiologyMicrobiologyYoung AdultVascular Biologyvon Willebrand FactorParasitic DiseasesmedicineAnimalsHumansBiologySchistosomaMucous MembraneReproductive SystemParasite PhysiologyPublic Health Environmental and Occupational Healthlcsh:RA1-1270biology.organism_classificationmedicine.diseaseSchistosoma haematobium infectionAfricaImmunologic TechniquesWomen's HealthParasitologyGenital Diseases FemalePLoS Neglected Tropical Diseases
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Quantification of the heterogeneity of prognostic cellular biomarkers in ewing sarcoma using automated image and random survival forest analysis

2014

Driven by genomic somatic variation, tumour tissues are typically heterogeneous, yet unbiased quantitative methods are rarely used to analyse heterogeneity at the protein level. Motivated by this problem, we developed automated image segmentation of images of multiple biomarkers in Ewing sarcoma to generate distributions of biomarkers between and within tumour cells. We further integrate high dimensional data with patient clinical outcomes utilising random survival forest (RSF) machine learning. Using material from cohorts of genetically diagnosed Ewing sarcoma with EWSR1 chromosomal translocations, confocal images of tissue microarrays were segmented with level sets and watershed algorithm…

PathologyCytoplasmMicroarrayslcsh:MedicineCohort StudiesMedicine and Health Scienceslcsh:ScienceMultidisciplinaryTissue microarrayApplied MathematicsPrognosisRandom forestBioassays and Physiological AnalysisOncologyFeature (computer vision)Research DesignPhysical SciencesBiomarker (medicine)SarcomaAnatomyAlgorithmsStatistics (Mathematics)Research Articlemedicine.medical_specialtyComputer and Information SciencesHistologyClinical Research DesignCD99Feature selectionBone NeoplasmsComputational biologySarcoma EwingBiology12E7 AntigenResearch and Analysis MethodsAntigens CDArtificial IntelligenceCell Line TumormedicineCancer Detection and DiagnosisBiomarkers TumorHumansStatistical MethodsCell Nucleuslcsh:RBiology and Life SciencesComputational BiologyImage segmentationmedicine.diseaselcsh:QCell Adhesion MoleculesMathematicsPLoS ONE
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Transfusion-associated graft-versus-host disease-report of two further cases with an immunohistochemical analysis

1994

Summary Transfusion-associated graft-vs.-host disease (tGVHD) is a severe disease usually affecting immunocompromised hosts with haematological neoplasia. Two patients with acute leukaemia are reported, who developed fatal tGVHD after blood transfusions. Intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1) and endothelial leucocyte adhesion molecule 1 (ELAM-1) expression and the CD4/CD8 ratio were assessed in lesional skin. ICAM-1 was strongly expressed on epidermal keratinocytes and endothelial cells (EC) and correlated with HLA-DR staining. VCAM-1 was strongly expressed on EC in the superficial dermal vessels. ELAM-1 stained weakly on EC in some of the su…

Pathologymedicine.medical_specialtyBlood transfusionCD3medicine.medical_treatmentIntercellular Adhesion Molecule-1CD4-CD8 RatioGraft vs Host DiseaseVascular Cell Adhesion Molecule-1CD18DermatologyTransfusion-associated graft versus host diseaseFatal OutcomeHumansLeukemia-Lymphoma Adult T-CellMedicineSkinbiologybusiness.industryCell adhesion moleculeTransfusion ReactionMiddle AgedIntercellular Adhesion Molecule-1medicine.diseaseLeukemia Myeloid AcuteLeukemiaImmunologybiology.proteinFemalebusinessCell Adhesion MoleculesCD8Clinical and Experimental Dermatology
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Coexpression of extracellular matrix glycoproteins undulin and tenascin in human autosomal dominant polycystic kidney disease.

1993

Autosomal dominant polycystic kidney disease (ADPKD) is the most common entity of cystic diseases of the kidney leading to end-stage renal insufficiency. Changes in extracellular matrix (ECM) are regarded to be an important pathogenic factor connected with the genes assumed to be responsible for human ADPKD. In order to assess the biological significance of altered expression and deposition of ECM glycoproteins for human ADPKD at molecular levels fresh-frozen tissue from ADPKD kidneys, fetal kidneys and normal adult kidneys were comparatively tested by immunohistochemistry for the presence of multifunctional ECM glycoproteins undulin, tenascin and fibronectin, interstitial collagen types I,…

Pathologymedicine.medical_specialtyCell Adhesion Molecules NeuronalAutosomal dominant polycystic kidney diseaseTenascinGene ExpressionKidneyExtracellular matrixFetusLamininTransforming Growth Factor betamedicineHumansRNA MessengerCells CulturedGlycoproteinsBasement membraneKidneyExtracellular Matrix Proteinsbiologyurogenital systemTenascinmedicine.diseasePolycystic Kidney Autosomal DominantImmunohistochemistryEpitheliumCell biologyFibronectinsFibronectinmedicine.anatomical_structurebiology.proteinCollagenLamininNephron
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Adhesion, growth and cytoskeletal characteristics of 8701-BC breast carcinoma cells cultured in the presence of type V collagen

1990

Type V collagen is one of the minor components of the extracellular matrix (ECM) whose content is increased in cases of ductal infiltrating carcinomas of the breast. In order to clarify its biological role, we have investigated the effect of this molecule, both as substrate and as soluble factor, on the behaviour of a breast carcinoma cell line (8701-BC) grown in vitro. Cell-collagen adhesion was monitored for 24 h from plating in the absence or presence of serum. The influence of type V collagen on cell growth was followed during 9 days of culture, and the actin-vinculin arrangement was studied by simultaneous fluorescent immuno-staining. The results indicate that type V collagen is not a …

Pathologymedicine.medical_specialtyCell growthBreast NeoplasmsAdhesionBiologyMolecular biologyIn vitroExtracellular matrixCytoskeletal ProteinsCarcinoma Intraductal NoninfiltratingOncologyCell cultureCell AdhesionTumor Cells CulturedmedicineHumansNeoplastic cellCollagenCytoskeletonBreast carcinomaCell DivisionEuropean Journal of Cancer and Clinical Oncology
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