Search results for "Administration"
showing 10 items of 5106 documents
Biocompatible Lipid Nanoparticles as Carriers to Improve Curcumin Efficacy in Ovarian Cancer Treatment
2017
Curcumin is a natural molecule with proved anticancer efficacy on several human cancer cell lines. However, its clinical application has been limited due to its poor bioavailability. Nanocarrier-based drug delivery approaches could make curcumin dispersible in aqueous media, thus overtaking the limits of its low solubility. The aim of this study was to increase the bioavailability and the antitumoral activity of curcumin, by entrapping it into nanostructured lipid carriers (NLCs). For this purpose here we describe the preparation and characterization of three kinds of curcumin-loaded NLCs. The nanosystems allowed the achievement of a controlled release of curcumin, the amounts of curcumin r…
Explanations of success and failure in management learning : What can we learn from Nokia's rise and fall
2016
International audience; In this paper, we study the changing explanations of success and failure over the course of a firm's history. We build on a discursive approach that highlights the role of narrative attributions in making sense of corporate performance. Specifically, we analyze how the Nokia Corporation was framed first as a success and later as a failure and how these dimensions of performance were explained in various actors' narrative accounts. In both the success and failure accounts, our analysis revealed a striking black-and-white picture that resulted in the institutionalization of Nokia's metanarratives of success and failure. Our findings also reveal a number of discursive a…
La negociación colectiva de los funcionarios públicos locales tras el Estatuto Básico del Empleado Público
2008

Impacts sensoriels et non-sensoriels de la modification d’un attribut d’un produit alimentaire sur ses quantités consommées
2012
Cette recherche examine l’effet de la modification d’un attribut aux effets indésirables (la teneur en alcool du vin) sur la consommation d’un produit. En adoptant une perspective sensorielle, nous testons si la baisse de la quantité de l’attribut du nouveau produit (vin à 9 % d’alcool au lieu de 13,5 %) a une influence physiologique sur les quantités consommées. De même, en adoptant une perspective cognitive, nous examinons si l’information sur la baisse de cet attribut influence également les quantités consommées. Une expérimentation a été mise en œuvre avec deux groupes appariés de 33 individus consommant, soit un vin allégé en alcool (9 % vol.), soit un vin normal (13,5 % vol.), ceci pe…
ENABLING LOCAL GOVERNMENTS TO DESIGN AND IMPLEMENT ANTI-CORRUPTION STRATEGIES THROUGH DYNAMIC PERFORMANCE MANAGEMENT AND GOVERNANCE. A CASE-STUDY OF …
2021
Lo scopo principale di questa ricerca è quello di inquadrare le possibili relazioni causali fra corruzione negli approvvigionamenti pubblici e performance delle amministrazioni locali. A tal fine, viene adottato un disegno di ricerca che integra dinamicamente metodi quantitativi e qualitativi in ogni fase del processo di studio. Gli approcci Dynamic Performance Management (DPM) e Governance (DPG), supportati da interviste approfondite non-strutturate, modellazioni formali e simulazioni quantitative, sono qui adottati per analizzare un caso di studio rappresentativo di un piccolo comune italiano in cui si sono verificati alcuni episodi di corruzione nelle attività di approvvigionamento nei p…
Day and Night Control of COPD and Role of Pharmacotherapy: A Review
2020
Abstract The topic of 24-hour management of COPD is related to day-to-night symptoms management, specific follow-up and patients’ adherence to therapy. COPD symptoms strongly vary during day and night, being worse in the night and early morning. This variability is not always adequately considered in the trials. Night-time symptoms are predictive of higher mortality and more frequent exacerbations; therefore, they should be a target of therapy. During night-time, in COPD patients the supine position is responsible for a different thoracic physiology; moreover, during some sleep phases the vagal stimulation determines increased bronchial secretions, increased blood flow in the bronchial circ…
Critères non financiers, motivations quant à leur utilisation et performance : analyses théorique et empirique.
2005
Co-Organisation Faculté Warocqué, Centre de Recherche Warocqué et HEC Montréal, Chaire de Gouvernance et Juricomptabilité
Le rôle du lieu dans l'expérience de consommation : une approche par le concept de valeur. Application au cas du spectacle vivant
2004
National audience; L'objectif de cet article est de proposer une réflexion sur le rôle du lieu dans lequel se déroule une expérience de consommation que ce soit un point de vente, un lieu de service, une salle de spectacle...Pour développer cette réflexion, nous distinguons deux niveaux d'analyse. Le premier niveau concerne l'expérience proposée par l'entreprise. Le but est de comprendre comment une entreprise peut utiliser l'environnement physique compris comme cadre de l'expérience en l'intégrant dans une offre d'expérience. Ce premier niveau d'analyse étant néanmoins insuffisant, nous avons développé parallèlement une réflexion concernant l'expérience vécue par le consommateur qui consti…
A Dialogical Exploration of Student Teacher Reflections: From Notions of Insideness and Outsideness to Pedagogical Alongsideness
2023
This article offers a dialogical exploration of student teachers’ reflections on notions of insideness and outsideness, the focal themes of an Erasmus+ ten-day intensive programme (IP). The arts-based, interdisciplinary IP involved 32 student participants and twelve members of staff from eight European universities hosted by the University of Jyväskylä, Finland. The data for this paper are based on the final written essays of student participants as they reflected on their understanding of outsideness and insideness at the end of the IP. The dialogic approach used in the analysis allows for a careful exploration of how the students attended to different experiences, surmised the meaning of …
Student Engagement and School Burnout in Finnish Lower-Secondary Schools: Latent Profile Analysis
2016
Self-ratings of behavioural engagement, cognitive engagement and school burnout were used in person-centred analyses to identify latent profiles among 2,485 Finnish lower-secondary school students. Three profiles were identified: high-engagement/low-burnout (40.6% of the sample), average-engagement/average-burnout (53.9%), and low-engagement/high-burnout (5.5%). Another sample of lower-secondary school students was used to validate the 3 profiles. The factors most strongly associated with the high-engagement/low-burnout profile of lower-secondary school students’ were high levels of support from teachers and family, good academic performance, and lack of truancy. The study indicated that te…