Search results for "Age factors"

showing 10 items of 1176 documents

Quantification of the risk of relapses after thyroid loboisthmusectomy for benign thyroid nodules

2006

AIM OF THE STUDY: To evaluate correlations between pre-operating epidemiological, clinical and diagnostic data and relapses concerning to patients operated on for benign thyroid nodules. MATERIAL AND METHODS: The AA. carried out a new ultrasonographic exam in 155 patients selected at random among 1012 treated by thyroid lobectomy between September 1976 and December 2002; 107 relapses were found (69%). The obtained data are analysed by chi2 test and a significant correlation between recurrence and data preceding first operation was found: non-homogeneous thyroid structure, multiple nodules, presence of peri-lesional halo, anti-thyroid antibodies, and non-adenomatous histological structure. C…

AdenomaAdultMaleChi-Square DistributionTime FactorsGoiterAge FactorsMiddle AgedGoitre relapse Thyroid lobectomyGraves DiseaseSex FactorsRecurrenceRisk FactorsThyroidectomyHumansFemaleThyroid NeoplasmsThyroid NoduleAgedFollow-Up StudiesGoiter NodularUltrasonography
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Age-dependent shift-to-the-right in the localization of colorectal adenomas.

1987

The age-dependent prevalence and topographical distribution of colorectal adenomas was investigated in 1006 unselected autopsies (554 males and 452 females) in Mainz, FRG. In 200 out of 1006 autopsies (19.8%) a total of 498 adenomas of the large intestine were detected. The percentage of patients with adenomas increased continuously with age. Only 6% of all adenomas were localized in the caecum and 8% in the rectum, whereas all the other adenomas were distributed rather evenly throughout the ascending colon (23%), the transverse colon (25%), the descending colon (15%) and the sigmoid colon (23%). Analyzing the topographical distribution of adenomas for definite age groups (40-59, 60-69, 70-…

AdenomaAdultMalemedicine.medical_specialtyendocrine system diseasesAdenomaAdolescentColorectal cancerRectumGastroenterologyPathology and Forensic MedicineDescending colonRisk FactorsInternal medicineMedicineAscending colonHumansLarge intestineMolecular BiologyAgedAged 80 and overbusiness.industryRectal NeoplasmsTransverse colonAge FactorsSigmoid colonCell BiologyGeneral MedicineMiddle Agedmedicine.diseasedigestive system diseasesstomatognathic diseasesmedicine.anatomical_structureColonic NeoplasmsFemalebusinessVirchows Archiv. A, Pathological anatomy and histopathology
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EXPRESSIONS OF DISCOMFORT IN ADOLESCENTS. CLINICAL REFLECTIONS RESULTING FROM AN EXPLORATORY STUDY OF A GROUP OF STUDENTS

2006

Obiettivo. Considerati la diffusione e l’incremento dei comportamenti aggressivi e violenti, specie quelli che trovano come radicale comune la mancanza di un’effettiva motivazione e l’efferatezza, la nostra ricerca si è posta l’obiettivo di rintracciare gli indicatori e i segni predittivi di tali comportamenti. La letteratura, inoltre, dimostra che gli indicatori e i segni predittivi di maggiore affidabilità sono quelli legati alle invarianti strutturali (per esempio le strategie difensive, la capacità di controllo degli impulsi). Metodi. È stato realizzato, con un piano di ricerca trasversale, uno studio clinico di confronto reclutando un gruppo di adolescenti (26 soggetti di sesso maschil…

Adolescent Adolescent Behavior*/psychology Age Factors Aggression Alcohol Drinking Attitude Automobile Driving Chi-Square Distribution Data Interpretation Statistical Education Female Humans Male Parent-Child Relations Risk-Taking Sex Factors Sexual Behavior Surveys and Questionnaires
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Celiac disease and selective immunoglobulin A deficiency

1997

Selective IgA deficiency was observed in 12 of 688 (1.7%) patients with celiac disease who were clinically undistinguishable from patients with celiac disease with normal IgA levels. This high prevalence of IgA deficiency in patients with celiac disease makes serum IgA assay advisable when screening for celiac disease is performed by measurement of antigliadin antibodies or anti-IgA endomysium antibodies. Similarly, subjects with IgA deficiency should be considered at risk of celiac disease.

AdolescentGlutensCross-sectional studyMuscle Fibers SkeletalDiseaseSelective IgA deficiencyImmunoglobulin EGliadinCoeliac diseaseMyofibrilsRisk FactorsImmunopathologyConfidence IntervalsDiet Protein-RestrictedPrevalencemedicineHumansChildChi-Square Distributionbiologybusiness.industryAge FactorsIgA DeficiencyInfantnutritional and metabolic diseasesmedicine.diseaseEndomysiumdigestive system diseasesImmunoglobulin ACeliac DiseaseIntestinal DiseasesCross-Sectional Studiesmedicine.anatomical_structureImmunoglobulin MChild PreschoolImmunoglobulin GPediatrics Perinatology and Child HealthImmunologybiology.proteinAntibodybusinessFollow-Up StudiesThe Journal of Pediatrics
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Triple negative breast cancer: shedding light onto the role of pi3k/akt/mtor pathway

2016

// Daniela Massihnia 1,* , Antonio Galvano 1,* , Daniele Fanale 1 , Alessandro Perez 1 , Marta Castiglia 1 , Lorena Incorvaia 1 , Angela Listi 1 , Sergio Rizzo 1 , Giuseppe Cicero 1 , Viviana Bazan 1 , Sergio Castorina 2,3,** and Antonio Russo 1,** 1 Department of Surgical, Oncological and Oral Sciences, Section of Medical Oncology, University of Palermo, Palermo, Italy 2 Fondazione Mediterranea “G.B. Morgagni”, Catania, Italy 3 Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy * These authors have contributed equally to this work ** Both the authors are last name Correspondence to: Antonio Russo, email: // Keywords : ER, HER2, PI3K/AKT/mTOR inhib…

Adult0301 basic medicineOncologymedicine.medical_specialtyPathologyAntineoplastic AgentsTriple Negative Breast NeoplasmsReviewTarget therapyPhosphatidylinositol 3-Kinases03 medical and health sciences0302 clinical medicineBreast cancerHER2Internal medicineDrug DiscoverymedicineCarcinomaHumansTriple negative breast cancerTarget therapyER; HER2; PI3K/AKT/mTOR inhibitor; Target therapy; Triple negative breast cancer; OncologySurvival rateProtein kinase BPI3K/AKT/mTOR pathwayTriple-negative breast cancerAgedClinical Trials as Topicbusiness.industryTOR Serine-Threonine KinasesAge FactorsMiddle Agedmedicine.diseaseOncogene Protein v-aktClinical trial030104 developmental biologyEROncology030220 oncology & carcinogenesisFemalePI3K/AKT/mTOR inhibitorbusinessSignal TransductionOncotarget
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In vitro model for DNA double‐strand break repair analysis in breast cancer reveals cell type–specific associations with age and prognosis

2016

Dysfunction of homologous recombination is a common denominator of changes associated with breast cancer-predisposing mutations. In our previous work, we identified a functional signature in peripheral blood lymphocytes from women who were predisposed that indicated a shift from homologous recombination to alternative, error-prone DNA double-strand break (DSB) repair pathways. To capture both hereditary and nonhereditary factors, we newly established a protocol for isolation and ex vivo analysis of epithelial cells, epithelial-mesenchymal transition cells (EMTs), and fibroblasts from breast cancer specimens (147 patients). By applying a fluorescence-based test system, we analyzed the error-…

Adult0301 basic medicinePathologymedicine.medical_specialtyEpithelial-Mesenchymal TransitionDNA RepairDNA repairCellBreast NeoplasmsBiologymedicine.disease_causeBiochemistry03 medical and health sciences0302 clinical medicineBreast cancerCell Line TumorGeneticsmedicineHumansDNA Breaks Double-StrandedGenetic Predisposition to DiseaseBreastEpithelial–mesenchymal transitionHomologous RecombinationMolecular BiologyAgedAged 80 and overAdenosine Diphosphate RiboseMutationAge FactorsMiddle AgedDNA repair protein XRCC4Prognosismedicine.diseaseDouble Strand Break Repair030104 developmental biologymedicine.anatomical_structure030220 oncology & carcinogenesisMutationCancer researchFemaleHomologous recombinationBiotechnologyThe FASEB Journal
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Adult attachment representation moderates psychotherapy treatment efficacy in clinically depressed inpatients

2016

Abstract Background We explored in a sample of clinically depressed patients the influence of attachment security and unresolved trauma on psychotherapeutic outcome as well as changes in attachment representation through psychotherapeutic intervention. Methods The sample consisted of 85 women (aged 19–52), 43 clinically depressed patients from a psychosomatic inpatient unit, and 42 healthy control subjects matched for age and education. Average length of hospitalization in the patient group was eight weeks. Attachment representations were assessed with the Adult Attachment Interview at the time of admission (baseline) and at discharge. Depressive symptoms were measured using the PHQ-9 at T1…

Adult050103 clinical psychologymedicine.medical_specialtyPsychotherapistNeuropsychological Testslaw.inventionYoung AdultRandomized controlled triallawIntervention (counseling)medicineHumans0501 psychology and cognitive sciencesYoung adultPsychiatryObject AttachmentDepression (differential diagnoses)Depressive DisorderInpatients05 social sciencesAge FactorsLength of StayMiddle AgedObject AttachmentTreatment efficacyPsychotherapyPsychiatry and Mental healthClinical PsychologyTreatment OutcomeInsecure attachmentFemalePsychologyAttachment measures050104 developmental & child psychologyClinical psychologyJournal of Affective Disorders
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Comparison of bipolar and tetrapolar impedance techniques for assessing fat mass.

2004

Whole body fat mass (BF) can be predicted by different bioimpedance (BIA) techniques measuring the whole body (tetrapolar hand-to-foot technique, HF), lower body (bipolar foot-to-foot technique, FF), or upper body (bipolar hand-to-hand technique, HH). This study analyzed 146 healthy volunteers (age 18-84 years) for whether these three techniques differ in their estimates of BF, and whether sex and age of the subjects influence estimates of BF. Reproducibility of the techniques was tested by calculating the technical error (TE). Effects of BIA technique, sex, and age on predicted BF were analyzed with ANOVA for repeated measurements in a mixed effect design. Results showed high reproducibili…

AdultAdolescentSensitivity and SpecificityFat massBody Mass IndexCohort StudiesAnimal scienceLower bodySex FactorsGermanyHealthy volunteersGeneticsElectric ImpedanceHumansEcology Evolution Behavior and SystematicsMathematicsAgedProbabilityAged 80 and overReproducibilityAnalysis of VarianceUpper bodyAge FactorsMiddle AgedSkinfold ThicknessAnthropologyMixed effectsBody CompositionFemaleAnalysis of varianceAnatomyBody mass indexAmerican journal of human biology : the official journal of the Human Biology Council
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Does recovery buffer against emotional labor in terms of motivational outcomes at work? Analyzing age differences among Finnish health care professio…

2017

• Emotional labor is a common job stressor among health care professionals and therefore more research evidence is needed concerning its buffers.

AdultAdolescentage differenceHealth Personnelwork motivationeducation050109 social psychologyterveydenhoitoemotionsYoung Adulttunteetemotional laborAdaptation Psychological0502 economics and businessHealth careHumans0501 psychology and cognitive sciencesFinlandGeneral Nursingta515AgedResearch evidenceta316Work motivationMotivationAge differencestyömotivaatiobusiness.industry05 social sciencesStressorAge FactorsMiddle Agedrecovery from workhealth carehumanitiesEmotional laborWork (electrical)ikäeroJob satisfactionPsychologybusinessStress Psychological050203 business & managementClinical psychologyApplied Nursing Research
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Age-Related Decline in Olympic Triathlon Performance: Effect of Locomotion Mode

2010

This study describes the decline in performance with age during Olympic triathlon Age Groups World Championships among the different locomotion modes. Mean performance of top 10 performers were analyzed for each group of age using the exponential model proposed by Baker, Tang, and Turner (2003, Experimental Aging Research, 29, 47-65). Comparison in performance decline was done between locomotion modes. Decline in performance in triathlon as a function of age follows an exponential model. A significant interaction effect between age and locomotion mode was observed on performance values. In swimming, a significant decrease was observed close to 5% per year after 45 years. Decline in performa…

AdultAged 80 and overMaleAnalysis of VarianceAgingTime FactorsAge FactorsMode (statistics)Athletic PerformanceMiddle AgedBicyclingRunningYoung AdultArts and Humanities (miscellaneous)Age groupsAge relatedHumansGeriatrics and GerontologyPsychologyhuman activitiesLocomotionSwimmingGeneral PsychologyAgedDemographyExperimental Aging Research
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