Search results for "Agrégation"
showing 10 items of 24 documents
Heparin-induced priapism
2001
Heparin-induced priapism constitutes a special form of pharmaco-induced prolonged erection, but the pathophysiological principles are not yet definitely clear. Heparin-induced antiplatelet-antibodies may lead to the aggregation of thrombocytes and thus alter the penile blood flow leading to low-flow priapism. Alternatively, this condition may be explained by initial high-flow priapism that later turns into ischemic priapism. The question remains whether hemorrhage with subsequent organisation of the hematoma and late fibrosis constitutes a pathogenetic factor. Besides this pathogenetic discussion, this paper presents the differential diagnosis of priapism as well as diagnostic and therapeut…
Etude des interactions dans la formation d'agrégats thermiques mixtes entre globulines de pois et béta-lactoglobuline : application à l'élaboration d…
2016
In the context of protein source diversification, pea protein is a promising ingredient and may be associated with milk proteins such as whey proteins in the production of new food products. In the present work, the thermal aggregation (85°C - 1 h) of pea globulins (Glob) alone and in admixture with β-lactoglobulin (βlg), prior to acid gelation, was studied as a function of total protein concentration, βlg/Glob weight ratio and ionic strength. The characterization of soluble aggregates was carried out by combining different analytical methods such as surface hydrophobicity determination, disulfide bridge quantification, dynamic light scattering (DLS), size exclusion chromatography (SEC-HPLC…
Contribution of a new dynamic climate regionalization protocol for estimating the water balance of Douglas-fir forests
2022
Quantifying the regionalized impacts of climate change on forests is a major ecologicaland socio-economic issue. The decline of Douglas-fir (Pseudotsuga menziesii) has been observed forabout 20 years and should be accelered. Recent work shows that regionalized estimation of waterbalance under forest canopy is hampered by the ability of regional climate models to correctlysimulate precipitation amount and seasonal cycle. Here we evaluate the ability of a new climateregionalization protocol to simulate a realistic precipitation regime required for the calculation offorest soil water balance.
The microscopic theory of diffusion-controlled defect aggregation
1998
Abstract The kinetics of diffusion-controlled aggregation of primary Frenkel defects ( F and H centers) in irradiated CaF 2 crystals is theoretically studied. Microscopic theory is based on the discrete-lattice formalism for the single defect densities (concentrations) and the coupled joint densities of similar and dissimilar defects treated in terms of the Kirkwood superposition approximation. Conditions and dynamics of the efficient F center aggregation during crystal heating after irradiation are analyzed.
Physico-chimie des lipopolysaccharides et réponse inflammatoire : rôle des lipoprotéines
2014
LPS is a potent bacterial pro-inflammatory agent, consisting of hydrophilic, polysaccharide part and of a lipid A which is considered like active moiety. Nevertheless, the O chain of LPS influences their aggregation in aqueous media. Therefore, our goal has been to determine the role of O chain on the LPS biological and physiopathological effects. Our work was organized according to three main axes, and led to the following findings :- development of a new LPS assay by LC-MS/MS. The combination of this new technique with LAL test allowed us to calculate an inactivation ratio which reflects the ability of host organism to inactivate LPS, especially through their transfer to HDL by PLTP. The …
On some flaws of university rankings: The example of the SCImago report
2012
International audience; Using France as our main example, we show there is a much scope for improving the SCImago ranking. We detect problems of nomenclature, double affiliation, aggregation and of bias toward large public-funded research organizations. The output per scholar is more important than the output per organization. The examples we cite suggest that only detailed knowledge of the situation can help in addressing the issue and take us beyond any automatic reading of the metadata.
The kinetics of defect aggregation: A novel lattice formalism
1995
We introduce a stochastic model for the A + B → O reaction on a discrete lattice. The system may include mono- and bimolecular steps (i. e. reaction and diffusion steps). The resulting infinite chain of equations is truncated at a certain level via a modified Kirkwood approximation.
Adapter localement les prévisions climatiques saisonnières : désagrégation stochastique et interpolation spatiale.
2013
6 pages; International audience; Un panorama est fait des méthodes de descente d’échelles permettant de passer de prévisions climatiques saisonnières de large-échelle à des séries locales journalières. L’exemple des générateurs stochastiques de temps est appliqué à la prévision des récoltes de sorgho au Kenya, dans le cadre du programme ANR PICREVAT. Une méthode d’interpolation spatiale des paramètres des générateurs est testée, pour obtenir des séries journalières de précipitations en tout point du territoire. Les séries générées sont utilisées en entrée du modèle agronomique SARRA-H.
BODIPY - phosphane - gold complexes : towards the elaboration of optical theranostics
2015
This work describes new anticancer agents that could be detected by optical imaging, namely optical theranostics.After a first chapter describing the context of cancer imaging and therapy, a second chapter describes a first series of BODIPY-phosphine-gold theranostics, the synthesis of which has been optimized (less steps, shortening the reaction time, scale up). Their conjugation with biomolecules (glucose, peptide) has been achieved by developing a simple and efficient method that leads to the coupling between the gold atom of the probe and the thiol of the biomolecule (modified or not), leading to a gold sulfur bound. Hence, it makes the biovectorization of the probes possible in order t…
SIX NUANCES D'A-GREY-GATION L'influence du choix des unités spatiales d'agrégation sur la lecture et l'interprétation des résultats cartographiés
2017
National audience; En même temps que les activités humaines se sont informatisées, les sources de données géographiques se sont diversifiées, autant du point de vue de leur production (smartphones, capteurs, simulation) que de leur gestion (modélisation, base de données et protocoles d’interrogation). Ces données de « nouvelle génération » partagent en général le fait d’être massives, désagrégées et multidimensionnelles. Elles se caractérisent par des attributs riches d’un point de vue spatial (localisation), thématique (type d’activité) et temporel (heure de début et de fin, durée). En contrepartie, leur volume et leur structure les rendent difficilesà manipuler (Batty, 2013 ; Kitchin, 201…