6533b7d7fe1ef96bd1267cbe

RESEARCH PRODUCT

Heparin-induced priapism

M BitzerR.a PustEkkehard W. HauckWolfgang WeidnerTh. DiemerChj KirkpatrickTh Bschleipfer

subject

AdultMalemedicine.medical_specialtyIschemic priapismHeparinbusiness.industryUrologyPriapismIschemiaHeparinurologic and male genital diseasesmedicine.diseaseSurgeryDiagnosis DifferentialHematomaInternal medicinemedicineCardiologyHumansPriapismDifferential diagnosisAgrégationbusinessmedicine.drug

description

Heparin-induced priapism constitutes a special form of pharmaco-induced prolonged erection, but the pathophysiological principles are not yet definitely clear. Heparin-induced antiplatelet-antibodies may lead to the aggregation of thrombocytes and thus alter the penile blood flow leading to low-flow priapism. Alternatively, this condition may be explained by initial high-flow priapism that later turns into ischemic priapism. The question remains whether hemorrhage with subsequent organisation of the hematoma and late fibrosis constitutes a pathogenetic factor. Besides this pathogenetic discussion, this paper presents the differential diagnosis of priapism as well as diagnostic and therapeutic procedures.

https://doi.org/10.1038/sj.ijir.3900759