Search results for "Alaria"

showing 10 items of 273 documents

¡No son las criaturas, es la Academia! Brechas salariales de género y carrera investigadora en la Universidad

2021

El objetivo del presente texto es presentar a la maternidad como argumento que naturaliza las dificultades de las mujeres en sus carreras académicas y que desplaza a los actuales criterios de evaluación científica. A partir de un estudio sobre la brecha salarial en la Universitat de València se identifican y se confrontan situaciones salariales como la penalización por maternidad y el plus salarial por paternidad para tratar de reconocer cómo opera una institución meritocrática. Se analiza el complemento salarial por sexenios que reconoce salarialmente la productividad de hombres y mujeres que ocupan posiciones estables en launiversidad y sus repercusiones en las distintas áreas de conocimi…

Gender StudiesInvestigacióPlus de paternidadUniversidadGeneral Arts and HumanitiesSexenios de investigaciónPenalización de maternidadBrechas salariales de géneroSocial Sciences (miscellaneous)
researchProduct

A framework for remission in SLE

2017

ObjectivesTreat-to-target recommendations have identified ‘remission’ as a target in systemic lupus erythematosus (SLE), but recognise that there is no universally accepted definition for this. Therefore, we initiated a process to achieve consensus on potential definitions for remission in SLE.MethodsAn international task force of 60 specialists and patient representatives participated in preparatory exercises, a face-to-face meeting and follow-up electronic voting. The level for agreement was set at 90%.ResultsThe task force agreed on eight key statements regarding remission in SLE and three principles to guide the further development of remission definitions:1. Definitions of remission wi…

Genetics and Molecular Biology (all)PediatricsAutoimmune diseasesNEPHRITIS PATIENTSDISEASE-ACTIVITYSeverity of Illness IndexBiochemistryRETROSPECTIVE ANALYSIS0302 clinical medicineQuality of lifePrednisoneAdrenal Cortex HormonesLupus Erythematosus SystemicImmunology and AllergyCHINESE PATIENTS030212 general & internal medicineSYSTEMIC-LUPUS-ERYTHEMATOSUSskin and connective tissue diseasesPREDICTORSOUTCOMESSystemic lupus erythematosusMalalties autoimmunitàriesRemission InductionSYSTEMIC-LUPUS-ERYTHEMATOSUS; DISEASE-ACTIVITY; RETROSPECTIVE ANALYSIS; INITIAL VALIDATION; NEPHRITIS PATIENTS; AMERICAN-COLLEGE; CHINESE PATIENTS; RENAL FLARES; PREDICTORS; OUTCOMESSymptom Flare UpConnective tissue diseaseManchester Institute for Collaborative Research on AgeingEstudi de casosOutcomes researchAntibodies AntinuclearDNA/immunologyImmunosuppressive Agentsmedicine.drugmedicine.medical_specialtyFarmacologiaResearchInstitutes_Networks_Beacons/MICRAConsensusImmunologyAdrenal Cortex Hormones/therapeutic useAMERICAN-COLLEGELupus Erythematosus Systemic/bloodSystemic Lupus ErythematosusGeneral Biochemistry Genetics and Molecular BiologyMaintenance Chemotherapy03 medical and health sciencesAntimalarialsRheumatologySeverity of illnessmedicineDisease Activity; Outcomes research; Systemic Lupus Erythematosus; Immunology and Allergy; Rheumatology; Immunology; Biochemistry Genetics and Molecular Biology (all)HumansDisease Activity030203 arthritis & rheumatologyPharmacologyAntibodies Antinuclear/bloodLupus erythematosusbusiness.industryTask forceConstruct validityRENAL FLARESComplement System ProteinsDNAINITIAL VALIDATIONDisease Activity; Outcomes research; Systemic Lupus Erythematosusmedicine.diseaseLupus eritematósAntimalarials/therapeutic usePhysical therapyImmunosuppressive Agents/therapeutic useComplement System Proteins/metabolismCase studiesOutcomes researchbusinessAnnals of the Rheumatic Diseases
researchProduct

New chromosome numbers for plant taxa endemic to the Balearic Islands

2006

Mitotic chromosome numbers are reported from 25 vascular plant taxa, endemic to the Balearic Islands that are poorly known cytogenetically. The chromosome numbers ofAnthyllis vulneraria subsp.balearica (2n=12),Cymbalaria fragilis (2n=56), andPolygonum romanum subsp.balearicum (2n=40) were determined for the first time. A new chromosome number was found in several populations ofAnthyllis hystrix (2n=70) suggesting that this species is decaploid, in contrast to an earlier work reporting a higher ploidy level (2n=12x=84). The new chromosome number 2n=32 was reported inHypericum hircinum subsp.cambessedesii. It is suggested that the previous count (2n=40) could be explained by the presence of a…

GeneticsB chromosomeGenusChromosome instabilityPaleontologyChromosomeAnthyllisCymbalariaPlant SciencePloidyBiologybiology.organism_classificationHystrixFolia Geobotanica
researchProduct

Phylogenetic relationships within the family Halomonadaceae based on comparative 23S and 16S rRNA gene sequence analysis.

2010

A phylogenetic study of the family Halomonadaceae was carried out based on complete 16S rRNA and 23S rRNA gene sequences. Several 16S rRNA genes of type strains were resequenced, and 28 new sequences of the 23S rRNA gene were obtained. Currently, the family includes nine genera (Carnimonas, Chromohalobacter, Cobetia, Halomonas, Halotalea, Kushneria, Modicisalibacter, Salinicola and Zymobacter). These genera are phylogenetically coherent except Halomonas, which is polyphyletic. This genus comprises two clearly distinguished clusters: group 1 includes Halomonas elongata (the type species) and the species Halomonas eurihalina, H. caseinilytica, H. halmophila, H. sabkhae, H. almeriensis, H. hal…

GeneticsHalomonasPhylogenetic treebiologyMolecular Sequence DataGenes rRNAGeneral MedicineSequence Analysis DNARibosomal RNAbiology.organism_classificationMicrobiologyDNA RibosomalBacterial Typing TechniquesHalomonadaceaeType speciesHalomonadaceaeRNA Ribosomal 23SSpecies Specificity23S ribosomal RNARNA Ribosomal 16SRibosomal DNAHalomonas salariaEcology Evolution Behavior and SystematicsPhylogenyInternational journal of systematic and evolutionary microbiology
researchProduct

Malaria in Italy. From an endemic to an imported disease

1998

GeographyAnthropologymedicineImported diseasemedicine.diseaseSocioeconomicsMalariaInternational Journal of Anthropology
researchProduct

Akutes Lungenversagen bei Malaria tropica in der Schwangerschaft: Erfolgreiche Behandlung durch extrakorporale CO2-Elimination

2008

Eine 32jahrige Schwangere (26. Schwangerschaftswoche) erkrankte am 6. Tag nach der Ruckkehr von einem Indonesienaufenthalt mit Fieber bis 42°C, hamolytischer Anamie (Hamoglobin 7,6 g/dl) und Thrombozytopenie (7000/µl). Es wurde eine Malaria diagnostiziert; eine Prophylaxe hatte sie nicht durchgefuhrt. Unter antiparasitarer Chemotherapie mit Chloroquin, Chinin und Pyrimethamin kam es zur Elimination der Parasiten (Makrogametozyten von Plasmodium falciparum) aus dem peripheren Blut. Im weiteren Verlauf entwickelte sich jedoch ein progredientes Lungenversagen und eine therapierefraktare Pneumonie, die zu einem »adult respiratory distress syndrome« (ARDS; Morel-Stadium 4) fuhrten. Bei drohendem…

GynecologyArtificial ventilationPediatricsmedicine.medical_specialtyARDSQuinineRespiratory distressbusiness.industryMalaria prophylaxismedicine.medical_treatmentGeneral Medicinemedicine.diseasePneumoniaRespiratory failuremedicinebusinessMalariamedicine.drugDMW - Deutsche Medizinische Wochenschrift
researchProduct

Interaction of iron(II)-heme and artemisinin with a peptide mimic of Plasmodium falciparum HRP-II

2007

Abstract The interaction of heme or heme-artemisinin adducts (heme-art) with different peptides mimicking repeat sequences of the Histidine-Rich-Protein-II of Plasmodium falciparum (PfHRP-II) was investigated. The pseudo-first order rate constants of the coordination of heme or heme-art onto a histidine rich peptide, used as a mimic of PfHRP-II putative heme binding sequence, are of the same order of magnitude, namely 42 and 14 s −1 , respectively. Despite the intrinsic reactivity of the carbonyl at C10 of heme-art toward a hydroxyl function, a peptide containing a serine or threonine residue does not readily react with heme-art adducts. Therefore, a much higher affinity of heme-art compare…

Heme bindingStereochemistryIronPlasmodium falciparumProtozoan ProteinsmalariaPeptide010402 general chemistry01 natural sciencesBiochemistryInorganic Chemistry03 medical and health scienceschemistry.chemical_compoundResidue (chemistry)[ SDV.BBM.BC ] Life Sciences [q-bio]/Biochemistry Molecular Biology/Biomolecules [q-bio.BM]hemozoinAnimals[SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry Molecular Biology/Biochemistry [q-bio.BM]hemeHemealkylationHistidineComputingMilieux_MISCELLANEOUS030304 developmental biologychemistry.chemical_classification0303 health sciencesMolecular StructurebiologyHemozoinMolecular MimicryProteinsPlasmodium falciparumbiology.organism_classificationArtemisininsProtein tertiary structure3. Good health0104 chemical sciencesKineticsModels ChemicalchemistryBiochemistryartemisininPeptidesProtein Binding
researchProduct

Digestive vacuole of Plasmodium falciparum released during erythrocyte rupture dually activates complement and coagulation.

2012

Abstract Severe Plasmodium falciparum malaria evolves through the interplay among capillary sequestration of parasitized erythrocytes, deregulated inflammatory responses, and hemostasis dysfunction. After rupture, each parasitized erythrocyte releases not only infective merozoites, but also the digestive vacuole (DV), a membrane-bounded organelle containing the malaria pigment hemozoin. In the present study, we report that the intact organelle, but not isolated hemozoin, dually activates the alternative complement and the intrinsic clotting pathway. Procoagulant activity is destroyed by phospholipase C treatment, indicating a critical role of phospholipid head groups exposed at the DV surfa…

HemeproteinsMalePain ThresholdErythrocytesImmunologyComplement Pathway AlternativePlasmodium falciparumVacuoleBiochemistryHemolysisMonocytesMicrobiologyHypesthesiaRats Sprague-DawleyPhagocytosisparasitic diseasesAnimalsHumansMalaria FalciparumBlood CoagulationLungbiologyPhospholipase CHemozoinDextran SulfatePlasmodium falciparumCell BiologyHematologyIntracellular Membranesbiology.organism_classificationComplement systemRatsAntibody opsonizationImmunologyVacuolesAlternative complement pathwaySpleenWaste disposalBlood
researchProduct

¿Cuánto y cómo estamos utilizando la encuesta de morbilidad hospitalaria?

1995

ResumenObjetivoLa Encuesta de Morbilidad Hospitalaria (EMH) es todavía la única estadística sistemática de ámbito nacional de la morbilidad atendida en los hospitales de España. Se pretende describir las publicaciones científicas relacionadas con la EMHMétodosSe ha realizado una revisión de la literatura científica española mediante una búsqueda bibliográfica automática en el Índice Médico Español (1971–1993), completada manualmente.ResultadosSe hallaron 31 publicaciones relacionadas con la EMH de las que 10 realizan una aplicación práctica de la información, 13 son estudios empíricos sobre la calidad de los documentos que sirven de soporte para la elaboración de la EMH y ocho reflexionan s…

Hospital surveyEncuesta hospitalariaPublic Health Environmental and Occupational HealthMorbilidad hospitalariaHospital morbidityGaceta Sanitaria
researchProduct

Distribution pattern of river blennies in the Júcar River basin (eastern Spain)

2000

Salaria fluviatilis in the Jucar river basin was found only in the Jucar River itself, the tributaries Cabriel and Escalona, and the irrigation channel Acequia Real. Blenny density varied from 0.2 to 3.1 ind m -2 Sites with blennies had significantly lower coliform counts than those without blennies.

HydrologygeographySalariageography.geographical_feature_categoryEcologyDrainage basinAquatic ScienceBiologybiology.organism_classificationSpatial distributionPopulation densityHabitatTributaryWater qualityWater pollutionEcology Evolution Behavior and SystematicsJournal of Fish Biology
researchProduct