Search results for "Alclofenac"

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Hydrophilic and Hydrophobic Polymeric Derivatives of Anti-Inflammatory Agents Such as Alclofenac, Ketoprofen, and Ibuprofen

1991

Macromolecular prodrugs of a hydrophilic polymer [α,β-poly( N- hydroxyethyl)-DL-aspartamide (PHEA)] was used as a drug carrier. Three poly- (HEA)-NSAID adducts were studied: poly(HEA)-Alclofenac, poly(HEA)-Keto profen, and poly(HEA)-Ibuprofen. Prodrugs with different drug content were synthesized both as water-soluble and water-insoluble agents. Hydrolysis of water-soluble adducts in a simulated gastric juice was studied.

Ketoprofenchemistry.chemical_classificationPolymers and PlasticsChemistrymedicine.drug_class0206 medical engineeringBioengineering02 engineering and technologyPolymerProdrugAlclofenac021001 nanoscience & nanotechnologyIbuprofen020601 biomedical engineeringAnti-inflammatoryAdductBiomaterialsPolymer chemistryMaterials ChemistrymedicineOrganic chemistry0210 nano-technologyDrug carriermedicine.drugJournal of Bioactive and Compatible Polymers

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