Search results for "Alder"
showing 10 items of 273 documents
Hot water injection in relation to 1982-84 microseismic events at Campi Flegrei Caldera by thermo-hydro-mechanical simulation
2020
The repeated deformations and seismic unrests at Campi Flegrei caldera (southern Italy) have been identified due to a fluid injection source in volcano active area. We investigated the role of hot water injection in the seismic unrests of 1982-1984 with a view to gaining insights into the caldera’s dynamics, by applying coupled TOUGHREACT-FLAC3D simulator to our computational domain of 10 × 1 × 3 km with a single-phase steam isothermal (HM) and non-isothermal (THM) simulations comparison. The results indicated that the overlying caprock blocks the uprising hot water injection, leading to the building up of pore pressure and shear stress underneath over time. This process substantially modif…
Pere Calders entre la ironia i la sàtira: «La ciutat cansada»
2011
«La ciutat cansada» és una novel·la inacabada, encara que deixada en un estat molt avançat d’escriptura (onze capítols i l’esquema d’un epíleg), de Pere Calders, publicada pòstumament l’any 2008. Va començar a ser escrita l’any 1944 i va ser abandonada definitivament l’any 1952, tot just dos anys abans de l’inici de la redacció de «Ronda naval sota la boira», enllestida l’any següent, encara que publicada més tard, l’any 1967. El present article analitza «La ciutat cansada» centrant sobretot l’interès en la relació conflictiva amb la poètica realista —tractament específic del narrador, dels personatges, de l’espai i del temps— i en la importància de la ironia, de la paròdia i de la sàtira. …
Evaluation of the inverse electron demand Diels-Alder reaction in rats using a scandium-44-labelled tetrazine for pretargeted PET imaging
2019
Background Pretargeted imaging allows the use of short-lived radionuclides when imaging the accumulation of slow clearing targeting agents such as antibodies. The biotin-(strept)avidin and the bispecific antibody-hapten interactions have been applied in clinical pretargeting studies; unfortunately, these systems led to immunogenic responses in patients. The inverse electron demand Diels-Alder (IEDDA) reaction between a radiolabelled tetrazine (Tz) and a trans-cyclooctene (TCO)-functionalized targeting vector is a promising alternative for clinical pretargeted imaging due to its fast reaction kinetics. This strategy was first applied in nuclear medicine using an 111In-labelled Tz to image TC…
Improving quality and safety in nursing homes and home care: the study protocol of a mixed-methods research design to implement a leadership interven…
2018
IntroductionNursing homes and home care face challenges across different countries as people are living longer, often with chronic conditions. There is a lack of knowledge regarding implementation and impact of quality and safety interventions as most research evidence so far is generated in hospitals. Additionally, there is a lack of effective leadership tools for quality and safety improvement work in this context.Methods and analysisThe aim of the ‘Improving Quality and Safety in Primary Care—Implementing a Leadership Intervention in Nursing Homes and Homecare’ (SAFE-LEAD) study is to develop and evaluate a research-based leadership guide for managers to increase quality and safety compe…
First combined flux chamber survey of mercury and CO2 emissions from soil diffuse degassing at Solfatara of Pozzuoli crater, Campi Flegrei (Italy): M…
2014
Abstract There have been limited studies to date targeting gaseous elemental mercury (GEM) flux from soil emission in enriched volcanic substrates and its relation with CO 2 release and tectonic structures. In order to evaluate and understand the processes of soil–air exchanges involved at Solfatara of Pozzuoli volcano, the most active zone of Campi Flegrei caldera (Italy), an intensive field measurement survey has been achieved in September 2013 by using high-time resolution techniques. Soil–air exchange fluxes of GEM and CO 2 have been measured simultaneously at 116 points, widely distributed within the crater. Quantification of gas flux has been assessed by using field accumulation chamb…
Diels–Alder reaction of β-fluoro-β-nitrostyrenes with cyclic dienes
2021
The Diels–Alder reaction of β-fluoro-β-nitrostyrenes with cyclic 1,3-dienes was investigated. A series of novel monofluorinated norbornenes was prepared in up to 97% yield. The reaction with 1,3-cyclohexadiene permits the preparation of monofluorinated bicyclo[2.2.2]oct-2-enes. The kinetic data of the reactions with 1,3-cyclopentadiene and 1,3-cyclohexadiene were used to calculate activation parameters. Furthermore, the synthetic utility of the cycloadducts obtained was demonstrated.
Panorámica de la desigualdad digital en España: operacionalización y dimensionamiento de las brechas digitales de accesibilidad, habilidades y formas…
2019
En este artículo, se realiza un análisis estadístico de la desigualdad digital en España a partir de una operacionalización de las tres brechas digitales más relevantes: (1) accesibilidad a los dispositivos TIC; (2) competencias y habilidades digitales; y (3) prácticas digitales y formas diferenciales de uso. La metodología es cuantitativa, basada en la última oleada (2018) de la encuesta sobre equipamientos tecnológicos en el hogar del INE (TIC-H), a partir de la cual se ha desarrollado un análisis comparativo por género, edad, nivel de estudios, situación laboral y tipo de hábitat residencial. Los resultados muestran cómo la desigualdad de acceso tiene actualmente más que ver con las moda…
Recovering a variable exponent
2021
We consider an inverse problem of recovering the non-linearity in the one dimensional variable exponent $p(x)$-Laplace equation from the Dirichlet-to-Neumann map. The variable exponent can be recovered up to the natural obstruction of rearrangements. The main technique is using the properties of a moment problem after reducing the inverse problem to determining a function from its $L^p$-norms.
One-pot cross-enyne metathesis (CEYM)-Diels-Alder reaction of gem-difluoropropargylic alkynes.
2013
Propargylic difluorides 1 were used as starting substrates in a combination of cross-enyne metathesis and Diels–Alder reactions. Thus, the reaction of 1 with ethylene in the presence of 2nd generation Hoveyda–Grubbs catalyst generates a diene moiety which in situ reacts with a wide variety of dienophiles giving rise to a small family of new fluorinated carbo- and heterocyclic derivatives in moderate to good yields. This is a complementary protocol to the one previously described by our research group, which involved the use of 1,7-octadiene as an internal source of ethylene.
Quantitative Approximation Properties for the Fractional Heat Equation
2017
In this note we analyse \emph{quantitative} approximation properties of a certain class of \emph{nonlocal} equations: Viewing the fractional heat equation as a model problem, which involves both \emph{local} and \emph{nonlocal} pseudodifferential operators, we study quantitative approximation properties of solutions to it. First, relying on Runge type arguments, we give an alternative proof of certain \emph{qualitative} approximation results from \cite{DSV16}. Using propagation of smallness arguments, we then provide bounds on the \emph{cost} of approximate controllability and thus quantify the approximation properties of solutions to the fractional heat equation. Finally, we discuss genera…