Search results for "Alix"

CCDC 288488: Experimental Crystal Structure Determination

2006

Related Article: A.Ahmen, M.Nissinen|2006|Chem.Commun.||1209|doi:10.1039/b515143k

CCDC 1449686: Experimental Crystal Structure Determination

2016

Related Article: Kaisa Helttunen, Maija Nissinen|2016|CrystEngComm|18|4944|doi:10.1039/C6CE00243A

ChemInform Abstract: Calixcrowns : Synthesis and Properties

2009

The synthesis and properties of calix[n]crowns (n = 4–8), calix[n]biscrowns and their related compounds, resorcinarene crowns, have been discussed and reviewed. These macrocycles exhibit remarkable ionophoric properties toward alkali and alkaline earth metal cations, as well as, to tertiary amines. The selectivity and efficiency of calixcrowns in binding cations have been attributed to their structural features, which include substituent effects and size of the crown ether moiety and, conformation of the parent calixarene.

Chemical and pharmaceutical evaluation of the relationship between triazole linkers and pore size on cyclodextrin–calixarene nanosponges used as carr…

2016

Mixed cyclodextrin–calixarene nanosponges were used to prepare some composites with the well known polyphenolic bioactive compounds quercetin and silibinin. The composites were characterized by means of different techniques (UV-vis, FT-IR, microcalorimetry, thermogravimetry), in order to assess their loading and thermal stability. The kinetics of release of the bioactive molecules into aqueous solution were studied at two different pH values (1.0, 6.4), which mimic typical physiological conditions. Finally the possible antiproliferative effects in vitro were assayed towards three triple negative breast cancer cell lines (SUM 149, SUM 159 and MDA-MB-23). Our results point out the role assume…

Calixarenes as Stationary Phases

2006

Synthesis and Photoluminescent Properties of 1,1‘-Binaphthyl-Based Chiral Phenylenevinylene Dendrimers

2003

New chiral, soluble binaphthyl derivatives that incorporate stilbenoid dendrons at the 6,6′-positions have been prepared. The synthesis of the new enantiopure dendrimers was performed in a convergent manner by Horner-Wadsworth-Emmons (HWE) reaction of the appropriately functionalized 1,1′-binaphthyl derivative (R)-1 and the appropriate dendrons (R)2nGn-CHO. Different electroactive units were incorporated in the peripheral positions of the dendrons in order to tune both the optical and electrochemical behavior of these systems. Fluorescence measurements on the chiral dendrimers reveal a strong emission with maxima between 409 and 508 nm depending upon the substitution pattern. Finally, t…

Double and triple calix[4]arenis connected via the oxygen functions

1990

New macrocyclic molecules are described containing two or three p-tert-butylcalix[4]arene subunits connected via their oxygen atoms. These macrocycles are available by two general methods which are capable of producing assemblies with bridges of varying rigidity and length.

Clicked and long spaced galactosyl- and lactosylcalix[4]arenes: New multivalent galectin-3 ligands

2014

Four novel calix[4]arene-based glycoclusters were synthesized by conjugating the saccharide units to the macrocyclic scaffold using the CuAAC reaction and using long and hydrophilic ethylene glycol spacers. Initially, two galactosylcalix[4]arenes were prepared starting from saccharide units and calixarene cores which differ in the relative dispositions of the alkyne and azido groups. Once the most convenient synthetic pathway was selected, two further lactosylcalix[4]arenes were obtained, one in the cone, the other one in the 1,3-alternate structure. Preliminary studies of the interactions of these novel glycocalixarenes with galectin-3 were carried out by using a lectin-functionalized chip…

Crystal and molecular structure of the (1 : 1) clathrate between a calix[4]arene containing onep-nitrophenol unit and toluene

1990

p-(Methyl,tert-butyl, nitro,tert-butyl) calix[4]arene: toluene, C37H41NO6. C7H8,Mr = 687.87, triclinic,\(P\bar 1\),a = 13.668(2),b = 12.187(2),c = 13.231(1) A,α = 106.78(8),β = 77.88(1),γ = 114.00(1)°,V = 1916.8(8) A3,Z = 2,Dx = 1.19 g cm−3,λ (CuKα) = 1.54178 A,μ = 5.90 cm−1,F(000) = 736,T = 293 K, finalR = 0.068 for 6309 observed reflections. This macrocycle, having different substituents at the positionspara to the hydroxyl groups, is the first one of its type to be studied. The general conformation of this calix[4]arene is compared to similar symmetrical ones. Thetert-butyl groups are not disordered as is usual and toluene is retained between the macrocycles. Two calixarene molecules are…

N-Alkyl Ammonium Resorcinarene Salts: A Versatile Family of Calixarene-Related Host Molecules

2016

This chapter presents a review of the recent advances in the chemistry of N-alkylammonium resorcinarenes salt receptors. The Mannich condensation between amines (primary and secondary) and resorcinarenes result in resorcinarene tetrabenzoxazines and tetra-azoxazines. Only 2 isomers out of 16 potential isomers are formed. The resorcinarene tetrabenzoxazines possess deeper cavities than the parent resorcinarenes which are suitable for binding neutral and cationic guests. In the presence of mineral acids, the six-membered oxazine ring in the resorcinarene tetrabenzoxazines is opened, resulting in N-alkylammonium resorcinarene salts (NARSs). The NARSs possess four spatially-fixed anions within …