Search results for "Allergic Rhinitis"

showing 10 items of 59 documents

Fish and seafood consumption during pregnancy and the risk of asthma and allergic rhinitis in childhood

2017

Background: It has been suggested that prenatal exposure to n-3 long-chain fatty acids protects against asthma and other allergy-related diseases later in childhood. The extent to which fish intake in pregnancy protects against child asthma and rhinitis symptoms remains unclear. We aimed to assess whether fish and seafood consumption in pregnancy is associated with childhood wheeze, asthma and allergic rhinitis. Methods: We pooled individual data from 60 774 mother-child pairs participating in 18 European and US birth cohort studies. Information on wheeze, asthma and allergic rhinitis prevalence was collected using validated questionnaires. The time periods of interest were: infancy (0-2 ye…

MaleMediterranean dietEpidemiologyCHILDRENCohort Studies0302 clinical medicineFish Fruit and Other FoodSurveys and QuestionnairesSeafood consumptionPrevalence030212 general & internal medicineseafoodChildPrenatal Nutritional Physiological Phenomena2. Zero hungermedicine.diagnostic_testJAPANESE INFANTSGeneral Medicine3. Good healthEuropeMEDITERRANEAN DIETLUNG-FUNCTIONChild PreschoolRegression AnalysisFemaleGeneration RpregnancyFATTY-ACIDSmedicine.symptomallergic rhinitiCohort studyFish consumptionWHEEZEAsthma - ChildrenECZEMA03 medical and health scienceschildrenEnvironmental healthWheezeFatty Acids Omega-3medicineAnimalsHumansRespiratory soundsRespiratory SoundsAsthmaPRENATAL EXPOSUREfishPregnancyallergic rhinitisWheezingwheezingbusiness.industryWheezing; allergic rhinitis; asthma; children; fish; pregnancy; seafoodMATERNAL FOOD-CONSUMPTIONInfant NewbornInfantasthmamedicine.diseaseRhinitis AllergicUnited States030228 respiratory systemAllergic rhinitis - ChildrenRelative riskGENERATION RHuman medicinebusinessInternational Journal of Epidemiology
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Efficacy of Buffered Hypertonic Saline Nasal Irrigation for Nasal Symptoms in Children with Seasonal Allergic Rhinitis: A Randomized Controlled Trial

2017

<b><i>Background:</i></b> Saline nasal irrigation is labelled as an add-on treatment in patients with allergic rhinitis (AR). The primary aim of this study was to compare the efficacy of 21-day use of buffered hypertonic saline (BHS) versus normal saline solution (NSS) on reducing nasal symptoms in children with seasonal AR (SAR). Comparing their efficacy on nasal cytology counts (NCC), quality of life, and sleep quality was the secondary aim. <b><i>Methods:</i></b> In this 21-day,<b> </b>open-label, randomized controlled study, 36 SAR children (aged 6-13 years) with a Total 5 Symptom Score (T5SS) ≥5 received twice-daily BHS or NSS…

MaleNeutrophilsmedicine.medical_treatmentSodium ChlorideGastroenterologylaw.inventionPittsburgh Sleep Quality IndexLeukocyte Count0302 clinical medicineQuality of lifeRandomized controlled triallawSurveys and QuestionnairesBuffered hypertonic solutionImmunology and AllergyChild030223 otorhinolaryngologyChildrenSalineHypertonicRhinitisNasal symptomGeneral MedicineNasal irrigationTreatment OutcomeNasal cytologyFemaleSaline SolutionNasal symptomsQuality of lifemedicine.medical_specialtyAdolescentSeasonal allergic rhinitisImmunology03 medical and health sciencesAllergicBuffered hypertonic solution; Children; Nasal cytology; Nasal symptoms; Quality of life; Seasonal allergic rhinitis; Adolescent; Child; Eosinophils; Female; Humans; Leukocyte Count; Male; Nasal Lavage; Neutrophils; Quality of Life; Rhinitis Allergic Seasonal; Saline Solution Hypertonic; Sodium Chloride; Surveys and Questionnaires; Treatment Outcome; Immunology and Allergy; ImmunologyInternal medicinemedicineHumansSaline Solution HypertonicSeasonalbusiness.industryRhinitis Allergic SeasonalNasal symptomsHypertonic salineEosinophils030228 respiratory systemNasal cytologyImmunologyNasal LavagebusinessInternational Archives of Allergy and Immunology
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Gastritis and gastroesophageal reflux disease are strongly associated with non-allergic nasal disorders

2021

AbstractBackgroundGastroesophageal reflux disease (GERD) has been reported to be significantly associated with chronic rhinosinusitis, but the strength of the association is still debated.AimsTo evaluate the strength of the association between gastritis/GERD and non-allergic rhinitis (NAR)/allergic rhinitis (AR)/sinusitis.MethodsWe investigated 2887 subjects aged 20–84 years, who underwent a clinical visit in seven Italian centres (Ancona, Palermo, Pavia, Terni, Sassari, Torino, Verona) within the study on Gene Environment Interactions in Respiratory Diseases, a population-based multicase-control study between 2008 and 2014. Subjects were asked if they had doctor-diagnosed “gastritis or sto…

MaleNon-allergic rhinitisGastroesophageal reflux diseaseGastroenterologyAllergic rhinitis0302 clinical medicinePrevalenceNon-allergic rhiniti030223 otorhinolaryngologySinusitisRhinitisAged 80 and overeducation.field_of_studyMiddle AgedGastrititItalyGastritisGastroesophageal RefluxFemalePublic HealthGastritismedicine.symptomResearch ArticleAdultPulmonary and Respiratory Medicinemedicine.medical_specialtyPopulationGastrititsSettore MED/10 - Malattie Dell'Apparato RespiratorioNOHiatal herniaGastritits Gastroesophageal refux disease Allergic rhinitis Non-allergic rhinitis SinusitisYoung Adult03 medical and health sciencesAllergic rhinitis; Gastritits; Gastroesophageal reflux disease; Non-allergic rhinitis; SinusitisInternal medicineAllergic rhinitimedicineHumansGastroesophageal refux diseaseSinusitiseducationAgedlcsh:RC705-779business.industrylcsh:Diseases of the respiratory systemmedicine.diseaseRhinitis AllergicSinusitidigestive system diseases030228 respiratory systemRelative riskChronic DiseaseGERDAllergic rhinitis; Gastritits; Gastroesophageal reflux disease; Non-allergic rhinitis; Sinusitis Public HealthNon-allergic rhinitisbusinessEsophagitis
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Trends in the prevalence of asthma and allergic rhinitis in Italy between 1991 and 2010

2012

The prevalence of asthma increased worldwide until the 1990s, but since then there has been no clear temporal pattern. The present study aimed to assess time trends in the prevalence of current asthma, asthma-like symptoms and allergic rhinitis in Italian adults from 1990 to 2010. The same screening questionnaire was administered by mail or phone to random samples of the general population (age 20-44 yrs) in Italy, in the frame of three multicentre studies: the European Community Respiratory Health Survey (ECRHS) (1991-1993; n=6,031); the Italian Study on Asthma in Young Adults (ISAYA) (1998-2000; n=18,873); and the Gene Environment Interactions in Respiratory Diseases (GEIRD) study (2007-2…

MalePediatricsCross-sectional study95% CI 1.19-1.59) from 1998-2000 to 2007-2010but since then there has been no clear temporal pattern. The present study aimed to assess time trends in the prevalence of current asthmaAbstract The prevalence of asthma increased worldwide until the 1990stemporal trendsSurveys and QuestionnairesEpidemiologySurveys and QuestionnaireMedicineasthma-like symptoms and allergic rhinitis in Italian adults from 1990 to 2010. The same screening questionnaire was administered by mail or phone to random samples of the general population (age 20-44 yrs) in ItalyYoung adultrespectively. The prevalence of current asthma was stable during the 1990s and increased (relative risk 1.38from 10.1% to 13.9% and from 16.8% to 25.8%education.field_of_studyAllergic rhinitis; Asthma; Epidemiology; Prevalence; Temporal trends; Wheezing;medicine.diagnostic_testSmokingthe median prevalence of current asthmaallergic rhinitis asthma epidemiology prevalence temporal trends wheezingItalyAbstract The prevalence of asthma increased worldwide until the 1990s but since then there has been no clear temporal pattern. The present study aimed to assess time trends in the prevalence of current asthma asthma-like symptoms and allergic rhinitis in Italian adults from 1990 to 2010. The same screening questionnaire was administered by mail or phone to random samples of the general population (age 20-44 yrs) in Italy in the frame of three multicentre studies: the European Community Respiratory Health Survey (ECRHS) (1991-1993; n=6031); the Italian Study on Asthma in Young Adults (ISAYA) (1998-2000; n=18873); and the Gene Environment Interactions in Respiratory Diseases (GEIRD) study (2007-2010; n=10494). Time trends in prevalence were estimated using Poisson regression models in the centres that repeated the survey at different points in time. From 1991 to 2010 the median prevalence of current asthma wheezing and allergic rhinitis increased from 4.1% to 6.6% from 10.1% to 13.9% and from 16.8% to 25.8% respectively. The prevalence of current asthma was stable during the 1990s and increased (relative risk 1.38 95% CI 1.19-1.59) from 1998-2000 to 2007-2010 mainly in subjects who did not report allergic rhinitis. The prevalence of allergic rhinitis has increased continuously since 1991. The asthma epidemic is not over in Italy. During the past 20 yrs asthma prevalence has increased by 38% in parallel with a similar increase in asthma-like symptoms and allergic rhinitis.mainly in subjects who did not report allergic rhinitis. The prevalence of allergic rhinitis has increased continuously since 1991. The asthma epidemic is not over in Italy. During the past 20 yrssymbolsasthma prevalence has increased by 38%FemaleepidemiologyHumanPulmonary and Respiratory MedicineAdult494). Time trends in prevalence were estimated using Poisson regression models in the centres that repeated the survey at different points in time. From 1991 to 2010in parallel with a similar increase in asthma-like symptoms and allergic rhinitismedicine.medical_specialtyRhinitis Allergic PerennialPopulationprevalencethe Italian Study on Asthma in Young Adults (ISAYA) (1998-2000Settore MED/10 - Malattie Dell'Apparato Respiratorio031)and the Gene Environment Interactions in Respiratory Diseases (GEIRD) study (2007-2010Settore MED/01 - Statistica Medicasymbols.namesakeYoung AdultAllergic rhinitiHumansRespiratory soundsPoisson regressioneducationAsthmaRespiratory SoundsCross-Sectional Studieallergic rhinitisbusiness.industrywheezingwheezing and allergic rhinitis increased from 4.1% to 6.6%Rhinitis Allergic Seasonalasthmain the frame of three multicentre studies: the European Community Respiratory Health Survey (ECRHS) (1991-1993medicine.disease873)Cross-Sectional Studiesn=10Relative riskTemporal trendRespiratory Soundn=6n=18business
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Pollen-induced allergic rhinitis in 1360 Italian children: comorbidities and determinants of severity

2013

BACKGROUND: Pollen-induced allergic rhinoconjunctivitis (AR) is highly prevalent and rapidly evolving during childhood. General practitioners may not be fully aware of the nature and severity of symptoms experienced by patients and might underestimate the prevalence of moderate or severe disease. Thus, the relevance of early diagnosis and intervention may be overlooked. OBJECTIVES: To investigate the severity of pollen-induced AR and its determinants in Italian children referred to allergy specialists and who had never received specific immunotherapy (SIT). METHODS: Children (age 4-18 yr) affected by pollen-induced AR who had never undergone SIT were recruited between May 2009 and June 2011…

MaleQuestionnairesAllergyPediatricsmultiple pollen sydromemultiple pollen syndromeBreastfeedingComorbidityAirborne allergenSurveys and QuestionnairesEpidemiologyPrevalenceImmunology and AllergyOutpatient clinicAge of OnsetChildConjunctivitis AllergicRhinitispan-allergens; multiple pollen syndrome; profilin; asthma; children; allergic rhinitis; epidemiology; italy; allergic conjunctivitisEnvironmental exposuremultiple pollen syndrome; Humans; profilin; Disease Progression; children; Child; Italy; Comorbidity; pan-allergens; Allergens; asthma; Male; Antigens Plant; Questionnaires; Age of Onset; Conjunctivitis Allergic; Skin Tests; epidemiology; Pollen; Child Preschool; Rhinitis Allergic Seasonal; allergic rhinitis; Early Diagnosis; allergic conjunctivitis; Female; PrevalenceAllergic conjunctivitisItalypan-allergensChild PreschoolpanallergenDisease ProgressionPollenepidemiologyFemaleallergic rhinitimedicine.medical_specialtyItaly; allergic conjunctivitis; allergic rhinitis; asthma; children; epidemiology; multiple pollen syndrome; pan-allergens; profilinImmunologyAllergicchildrenmedicineHumansprofilinallergic conjunctivitiAntigensPreschoolAsthmaSkin TestsSettore MED/38 - Pediatria Generale e SpecialisticaSeasonalallergic rhinitisbusiness.industryallergic rhinitis; allergic conjunctivitis; asthma; children; epidemiology; Italy; multiple pollen syndrome; pan-allergens; profilinRhinitis Allergic SeasonalPlantAntigens PlantAllergensasthmamedicine.diseaseConjunctivitispan-allergenallergic conjunctivitisEarly DiagnosisPediatrics Perinatology and Child Healthbusiness
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Comparative Effect of Beclomethasone Dipropionate and Cetirizine on Acoustic Rhinometry Parameters in Children With Perennial Allergic Rhinitis: A Ra…

2018

Background and objectives The effect of intranasal corticosteroids and oral antihistamines on acoustic rhinometry parameters has not been directly compared. The primary objective was to compare the effect of a 21-day course of treatment with nasal beclomethasone dipropionate (nBDP) with that of cetirizine (CTZ) on nasal patency measured using acoustic rhinometry in children with perennial allergic rhinitis (PAR). The secondary objective was to compare the effect of both drugs on nasal cytology, symptom severity, sleep quality, and quality of life. Methods In this 21-day, open-label, randomized controlled study, 34 children with PAR (age 6-14 years) with a Total 5-Symptom Score (T5SS) ≥5 rec…

MaleRhinometry Acousticmedicine.medical_specialtyRhinitis Allergic PerennialAdolescentNasal patencyNostrilImmunologyAnti-Inflammatory AgentsGastroenterologyAllergic rhinitislaw.inventionPittsburgh Sleep Quality Index03 medical and health sciences0302 clinical medicineAcoustic rhinometryRandomized controlled trialQuality of lifelawInternal medicineSurveys and QuestionnairesAllergic rhinitimedicineImmunology and AllergyHumans030212 general & internal medicineChildBeneficial effectsChildrenAdministration Intranasalbusiness.industryBeclomethasoneCetirizineCetirizineBeclomethasone dipropionatemedicine.anatomical_structureQuality of LifeNasal administrationFemaleAcoustic rhinometrybusiness030217 neurology & neurosurgerymedicine.drugJournal of investigational allergologyclinical immunology
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Clinical importance of eosinophil count in nasal fluid in patients with allergic and non-allergic rhinitis

2009

Eosinophil count in nasal fluid (ECNF) was used to differentiate nasal pathologies. Receiver Operating Characteristic (ROC) curve analysis and the area under the curve (AUC) were performed to evaluate the ECNF's accuracy in distinguishing allergic rhinitis (AR) from non-allergic rhinitis (NAR). We also evaluated the accuracy of ECNF in recognizing patients with mild and severe symptoms of rhinitis and patients with ineffective and effective clinical responses to antihistamines. 1,170 consecutive adult patients with a clinical history of rhinitis were studied. ECNF's median in AR was 6.0 and 2.0 in NAR and the best cut-off value was > 3.0, AUC = 0.75. ECNF's median in AR with mild nasal …

MaleSettore MED/09 - Medicina InternaNon-allergic rhinitisSeverity of Illness IndexGastroenterologyLeukocyte CountImmunology and AllergyClinical severityRhinitisAged 80 and overArea under the curvenasal fluidMiddle AgedTreatment Outcomemedicine.anatomical_structureArea Under CurveFemalenon-allergic rhinitiseosinophil count; nasal fluid; allergic rhinitis; non-allergic rhinitisAdultmedicine.medical_specialtyRhinitis Allergic PerennialAdolescenteosinophil countImmunologyHistamine AntagonistsDiagnosis DifferentialYoung AdultPredictive Value of TestsInternal medicinemedicineHumansIn patientAgedNasal fluidPharmacologyallergic rhinitisReceiver operating characteristicbusiness.industryPatient Selectioneosinophil count in nasal fluid allergic rhinitis non allergic rhinitisreceiveroperating characteristic curveCurve analysisRhinitis Allergic SeasonalEosinophilNasal Lavage Fluidmedicine.diseaseEosinophilsROC Curvebusiness
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Sleep apnea risk in subjects with asthma with or without comorbid rhinitis

2014

BACKGROUND: As many as 80% of patients with asthma suffer from allergic rhinitis (AR), and rhinitis symptoms are associated with sleep complaints The aim of this cross-sectional study was to assess the prevalence of obstructive sleep apnea syndrome risk in patients with asthma and to explore the association between comorbid rhinitis and obstructive sleep apnea syndrome risk. METHODS: Subjects with asthma were recruited by general practitioners during a control visit. Physicians compiled a questionnaire that assessed the presence of AR according to ARIA (Allergic Rhinitis and Its Impact on Asthma) guidelines and factors influencing the risk of obstructive sleep apnea syndrome (gastroesophage…

MaleTime FactorsSettore MED/10 - Malattie dell'Apparato RespiratorioComorbidityCritical Care and Intensive Care MedicineSeverity of Illness IndexRisk FactorsSurveys and QuestionnairesPrevalenceSurveys and QuestionnaireRhinitisriskSleep Apnea ObstructiveMedicine (all)ApneaSleep apneaGeneral MedicineMiddle Agedsleep apneaFemalemedicine.symptomAllergic rhinitis; Asthma; Obstructive sleep apnea syndrome; Risk; Sleep apnea; STOP-BANG; Pulmonary and Respiratory Medicine; Critical Care and Intensive Care MedicineHumanPulmonary and Respiratory MedicineAdultmedicine.medical_specialtyTime Factorobstructive sleep apnea syndromeAllergicInternal medicineSTOP-BANGSeverity of illnessmedicineAllergic rhinitiHumansAsthmaCross-Sectional Studieallergic rhinitisbusiness.industryObstructiveRisk FactorSTOP-BANG; allergic rhinitis; asthma; obstructive sleep apnea syndrome; risk; sleep apneaOdds ratioasthmamedicine.diseaseObesityComorbidityRhinitis Allergicrespiratory tract diseasesObstructive sleep apneaAllergic rhinitis; Asthma; Obstructive sleep apnea syndrome; Risk; Sleep apnea; STOP-BANG; Adult; Asthma; Comorbidity; Cross-Sectional Studies; Female; Humans; Male; Middle Aged; Prevalence; Rhinitis Allergic; Risk Factors; Severity of Illness Index; Sleep Apnea Obstructive; Surveys and Questionnaires; Time FactorsCross-Sectional StudiesPhysical therapybusiness
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Endotyping Seasonal Allergic Rhinitis in Children: A Cluster Analysis.

2022

BackgroundSeasonal Allergic Rhinitis (SAR) is a heterogeneous inflammatory disease. We hypothesized that a cluster analysis based on the evaluation of cytokines in nasal lavage (NL) could characterize distinctive SAR endotypes in children.MethodsThis cross-sectional study enrolled 88 children with SAR. Detailed medical history was obtained by well-trained physicians. Quality of life and sleep quality were assessed through standardized questionnaires [Pediatric Rhinoconjunctivitis Quality of Life Questionnaire (PRQLQ) and Pittsburgh Sleep Quality Index (PSQI) respectively]. Children were grouped through K-means clustering using Interleukin (IL)-5, IL-17, IL-23, and Interferon (INF)-γ in NL.R…

Medicine (General)R5-920allergic rhinitischildrenendotypesallergic rhinitis children cluster analysis cytokines endotypesGeneral Medicinecytokinescluster analysisFrontiers in medicine
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Lipid nanoparticles as delivery vehicles for the Parietaria judaica major allergen Par j 2

2011

Maria Luisa Bondì1,*, Giovanna Montana2,*, Emanuela Fabiola Craparo3, Roberto Di Gesù3, Gaetano Giammona3, Angela Bonura2, Paolo Colombo21Istituto per lo Studio dei Materiali Nanostrutturati, 2Istituto di Biomedicina ed Immunologia Molecolare, Consiglio Nazionale delle Ricerche, 3Laboratory of Biocompatible Polymers, Dipartimento di Scienze e Tecnologie Molecolari e Biomolecolari Stembio, Università di Palermo, Palermo, Italy *These authors contributed equally to this workAbstract: Parietaria pollen is one of the major causes of allergic reaction in southern Europe, affecting about 30% of all allergic patients in this area. Specific immunotherapy is the only…

ParietariaMembrane lipidsBiophysicsPharmaceutical Sciencerecombinant allergensEnzyme-Linked Immunosorbent AssayBioengineeringmedicine.disease_causelaw.inventionBiomaterialsMembrane LipidsAllergenlawInternational Journal of NanomedicineParietaria judaica (Par j)Drug DiscoverySolid lipid nanoparticlemedicineHumansParticle SizePyrophosphatasesOriginal ResearchPlant ProteinsDrug Carriersallergic rhinitisbiologyPhosphoric Diester HydrolasesChemistryOrganic ChemistryRhinitis Allergic SeasonalGeneral MedicineAllergensbiology.organism_classificationMolecular biologyRecombinant ProteinsBasophilssolid lipid nanoparticlesBiochemistrySettore CHIM/09 - Farmaceutico Tecnologico Applicativodrug deliveryDrug deliveryParietaria judaicaRecombinant DNAsolid lipid nanoparticles Parietaria judaica (Par j) drug delivery recombinant allergens specific immunotherapy allergic rhinitis.NanoparticlesEmulsionsImmunotherapyDrug carrierspecific immunotherapyInternational Journal of Nanomedicine
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