Search results for "Alter"
showing 10 items of 2368 documents
Potato (Solanum tuberosum) Juice Exerts an Anticonvulsant Effect in Mice through Binding to GABA Receptors
2008
Naturally occurring benzodiazepines have been identified in regular food such as wheat and potato, but there is still no evidence that potato extracts can affect CNS responses in vivo. Here we found that undiluted potato juice and potato juice diluted with saline 1 : 2 administered 10 min intracisternally ( I. C.) and 30 min per os before bicuculline exerted significant anticonvulsant activity in the bicuculline-induced seizure threshold test in mice. In vitro, potato juice from different harvests at dilution series from 10 % to 0.000001 %, diluted 100,000-fold, displaced 50 % of gamma-aminobutyric acid (GABA) receptor ligand [ (3)H]GABA and diluted 40-fold displaced 50 % of [(3)H]flunitraz…
DSM-IV Combined Type ADHD Shows Familial Association With Sibling Trait Scores
2008
Contains fulltext : 69060.pdf (Publisher’s version ) (Closed access) Attention deficit hyperactivity disorder (ADHD) is a discrete clinical syndrome characterized by the triad of inattention, hyperactivity, and impulsivity in the context of marked impairments. Molecular genetic studies have been successful in identifying genetic variants associated with ADHD, particularly with DSM-IV inattentive and combined subtypes. Quantitative trait locus (QTL) approaches to linkage and association mapping have yet to be widely used in ADHD research, although twin studies investigating individual differences suggest that genetic liability for ADHD is continuously distributed throughout the population, u…
Unstructural Biology of TRP Ion Channels: The Role of Intrinsically Disordered Regions in Channel Function and Regulation
2021
The first genuine high-resolution single particle cryo-electron microscopy structure of a membrane protein determined was a transient receptor potential (TRP) ion channel, TRPV1, in 2013. This methodical breakthrough opened up a whole new world for structural biology and ion channel aficionados alike. TRP channels capture the imagination due to the sheer endless number of tasks they carry out in all aspects of animal physiology. To date, structures of at least one representative member of each of the six mammalian TRP channel subfamilies as well as of a few non-mammalian families have been determined. These structures were instrumental for a better understanding of TRP channel function and …
Alla ricerca della sicurezza e della qualità: il modello di miglioramento dell'Oncologia Medica nel Policlinico Universitario di Palermo
2015
[In search of safety and quality: the improvement model proposed by the Oncology Department of the Palermo University] Over the past 20 years the field of oncology has product therapeutic innovations that have radically changed the prognosis of the most prevalent malignancies, since introduction of so-called targeted molecular agents. As a result of these changes, also the management of cancer patients has become more complex requiring technologies and skills that involve many professionals (medical oncologists, biologists, molecular geneticists, surgeons, pathologists, radiologists, nurses and psychologists), each engaged in a different stage of the disease, with the common goal of ensurin…
Comparative evaluation between glass and polyethylene fiber reinforced composites: A review of the current literature
2017
Background Fiber reinforced composite (FRC) is a promising class of material that gives clinicians alternative treatment options. There are many FRC products available in the market based on either glass or polyethylene fiber type. The aim of this study was to present a comparison between glass and polyethylene fiber reinforced composites based on available literature review. Material and methods A thorough literature search, with no limitation, was done up to June 2017. The range of relevant publications was surveyed using PubMed and Google Scholar. From the search results, articles related to our search terms were only considered. An assessment of these articles was done by two individual…
Trading activity and price impact in parallel markets: SETS vs. off-book market at the London Stock Exchange
2011
We empirically study the trading activity in the electronic on-book segment and in the dealership off-book segment of the London Stock Exchange, investigating separately the trading of active market members and of other market participants which are non-members. We find that (i) the volume distribution of off-book transactions has a significantly fatter tail than the one of on-book transactions, (ii) groups of members and non-members can be classified in categories according to their trading profile (iii) there is a strong anticorrelation between the daily inventory variation of a market member due to the on-book market transactions and inventory variation due to the off-book market transac…
CONSTRUCTION OF THE SOCIAL IMAGINARY OF ALTERNATIVE THERAPIES THROUGH DISCOURSE IN SOCIAL NETWORKS: CASE STUDY OF THE CHANNEL "ALTERNATIVE THERAPIES …
2019
Resumen: El objetivo de esta investigación es analizar cómo se construye el imaginario social de las terapias naturales, complementarias y alternativas a través de su discurso en redes sociales. Para ello, se ha escogido el canal temático “Terapias alternativas y remedios naturales” de la plataforma YouTube. Se ha realizado un análisis de contenido de dicho canal y se han examinado las sinergias con la página de Facebook, y el sitio web que se vinculan al mismo, con la finalidad de determinar si, además de contribuir en la difusión de estas terapias, existe una intencionalidad distinta. El periodo de análisis del canal temático ha sido de un año: desde julio de 2017 a julio de 2018. Se ha s…
Animation attracts: The attraction effect in an on-line shopping environment
2006
Two studies examine the attraction effect - an inconsistent choice behavior typically observed when consumers are presented with two products (target and competitor), both good for different reasons, and a worse "decoy" - in the context of on-line consumer decisions with different product displays (animated or static). The experiments, with different participant populations, show that the attraction effect in an on-line shopping environment depends on the animation format of the products. Experiment 1 (with Italian participants) suggests that the attraction effect is eliminated when target and competitor are both animated and is accentuated when the target is animated and the competitor is …
CONSTRUCCIÓN DEL IMAGINARIO SOCIAL DE LAS TERAPIAS ALTERNATIVAS A TRAVÉS DEL DISCURSO EN REDES SOCIALES: CASO DE ESTUDIO DEL CANAL “TERAPIAS AL…
2019
Resumen: El objetivo de esta investigación es analizar cómo se construye el imaginario social de las terapias naturales, complementarias y alternativas a través de su discurso en redes sociales. Para ello, se ha escogido el canal temático “Terapias alternativas y remedios naturales” de la plataforma YouTube. Se ha realizado un análisis de contenido de dicho canal y se han examinado las sinergias con la página de Facebook, y el sitio web que se vinculan al mismo, con la finalidad de determinar si, además de contribuir en la difusión de estas terapias, existe una intencionalidad distinta. El periodo de análisis del canal temático ha sido de un año: desde julio de 2017 a julio de 2…
Subalternità e filosofia della storia. Appunti sul carteggio Marx-Zasulič
2021
this article proposes, through the Gramscian political-pedagogical category of subalternity, a reading of the brief exchange of letters at the beginning of 1881 between Karl Marx and Vera Zasulič, a russian revolutionary militant at that time member of the populist group Čërnyj peredel (black repartition), on an issue of great importance for the russian socialist movement: the obščina, or that specific form of common ownership of land by russian peasants. to this end, it is necessary to analyze the chapter XXiV of the first book of Capital, in which Marx outlines the historical genesis of capitalism in Western europe and, in particular, in england, through the phenomenon of «the so-called o…