Search results for "Altera"
showing 10 items of 116 documents
A laboratory cave for the study of wall degradation in rock art caves : an implementation in the Vézère area
2013
The aim of this proposal is to present an original approach to the study and preservation of rock art caves. A multidisciplinary study of cave wall alteration will be performed to understand the impact of environmental context on the evolution of wall surfaces. The approach involves the choice of a cave with characteristics similar to painted caves in the studied area (Vézère Valley in Dordogne, France): e.g., cave wall alteration, lithology, morphology, etc. This selected cave is intended to become a laboratory cave, monitored for the acquisition of chemical, physical and biological environmental data on bedrock, air and fluids along with their characteristics. A cave without art or archae…
Spectral, mineralogical, and geochemical variations across Home Plate, Gusev Crater, Mars indicate high and low temperature alteration
2009
Over the last ~3 years in Gusev Crater, Mars, the Spirit rover observed coherent variations in color, mineralogy, and geochemistry across Home Plate, an ~80 m-diameter outcrop of basaltic tephra. Observations of Home Plate from orbit and from the summit of Husband Hill reveal clear differences in visible/near-infrared (VNIR) colors between its eastern and western regions that are consistent with mineralogical compositions indicated by Mössbauer spectrometer (MB) and by Miniature Thermal Emission Spectrometer (Mini-TES). Pyroxene and magnetite dominate the east side, while olivine, nanophase Fe oxide (npOx) and glass are more abundant on the western side. Alpha Particle X-Ray Spectromet…
El capitalismo, contra el planeta / 5
2007
Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead
2015
Goodson, William H. et al.
Influence of segmental chromosome abnormalities on survival in children over the age of 12 months with unresectable localised peripheral neuroblastic…
2014
Background: The prognostic impact of segmental chromosome alterations (SCAs) in children older than 1 year, diagnosed with localised unresectable neuroblastoma (NB) without MYCN amplification enrolled in the European Unresectable Neuroblastoma (EUNB) protocol is still to be clarified, while, for other group of patients, the presence of SCAs is associated with poor prognosis. Methods: To understand the role of SCAs we performed multilocus/pangenomic analysis of 98 tumour samples from patients enrolled in the EUNB protocol. Results: Age at diagnosis was categorised into two groups using 18 months as the age cutoff. Significant difference in the presence of SCAs was seen in tumours of patients…
Implantation of a polycaprolactone scaffold with subchondral bone anchoring ameliorates nodules formation and other tissue alterations
2015
Purpose: Articular cartilage has limited repair capacity. Two different implant devices for articular cartilage regeneration were tested in vivo in a sheep model to evaluate the effect of subchondral bone anchoring for tissue repair. Methods: The implants were placed with press-fit technique in a cartilage defect after microfracture surgery in the femoral condyle of the knee joint of the sheep and histologic and mechanical evaluation was done 4.5 months later. The first group consisted of a biodegradable polycaprolactone (PCL) scaffold with double porosity. The second test group consisted of a PCL scaffold attached to a poly(L-lactic acid) (PLLA) pin anchored to the subchondral bone. Result…
TOWARDS COLORECTAL CANCER STEM CELLS TARGETING: INVESTIGATING GENETIC AND EPIGENETIC LANDSCAPE
2022
New ways of looking into handwritten miscellanies of the seventeenth century: the case of “Spes Altera”
2020
A large number of copies of Shakespeare’s Sonnet 2 circulated in handwritten miscellanies from the second quarter of the Seventeenth Century. Eleven of those copies have significant variant readings that have led critics to put forward different hypotheses regarding their nature and quality. Most critics, taking into account stylometric analyses, have regarded them as early drafts of Shakespeare’s printed version, and have agreed on their poor quality.By paying due attention to the text’s context of production and reception, we have reached a different conclusion regarding both the nature and quality of the handwritten versions of Sonnet 2. In our view, they are the product of a conscious r…
Are the leukocyte telomere length attrition and telomerase activity alteration potential predictor biomarkers for sporadic TAA in aged individuals?
2014
A large variability in occurrence, complications, and age/gender manifestations characterizes individual susceptibility of sporadic thoracic aortic aneurysms (TAA), even in subjects with the same risk factor profiles. The reasons are poorly understood. On the other hand, TAA pathophysiology mechanisms remain unclear than those involved in abdominal aorta aneurysms. However, recent evidence is suggesting a crucial role of biological ageing in inter-individual risk variation of cardiovascular diseases, including sporadic TAA. Biological age rather than chronological age is a better predictor of vascular risk. Relevant assumptions support this concept. In confirming this evidence and our preli…
Genotoxicity of the fungicide dichlofluanid in seven assays
1991
Seven different endpoints for detection of genotoxicity have been used to demonstrate the DNA-altering properties of Dichlofluanid, a fungicide commonly used in viticulture pest control. Each endpoint (DNA synthesis inhibition test, alkaline viscosimetry, umu-test, alkaline filter elution, FADU-test, 32P-postlabeling, and electron microscopy) shows clear evidence of genotoxicity. These data indicate that application of the fungicide dichlofluanid may be mutagenic and/or carcinogenic for exposed humans.