Search results for "Alternative"

showing 10 items of 1466 documents

Circular RNA in Exosomes

2018

Circular RNAs (circRNAs) are a novel family of non-coding endogenous RNAs discovered in all eukaryotic cells and generated through a particular mechanism of alternative splicing called “back-splicing”. These molecules show multiple functions, by acting as modulators of gene and miRNA expression, and may have a role in several biological processes, such as cell proliferation and invasion with, tumour development and progression, and in several mechanisms underlying other diseases. Their presence has been shown to be abundant in several body fluids such as blood and saliva. Based on their biogenesis mechanism, cir- cRNAs may be categorized into five classes: exonic circRNAs, intronic circRNAs…

(circRNAs)0301 basic medicineSettore MED/06 - Oncologia MedicaAlternative splicingBiomarkerCDR1asBiologyExosomesExosomeNon-coding RNAsMicrovesiclesCell biology03 medical and health sciences030104 developmental biologyCircular RNAmicroRNASense (molecular biology)Circular RNAGeneBiogenesis
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Essential Oil Yield, Chemical Composition, and Total Citral Content of Nine Cultivars of Cymbopogon Species from Western India

2016

ABSTRACTThe essential oil composition of five elite Cymbopogon varieties (OD-19, Pragati, RRL-16, NLG-84) and a hybrid (CPK-25) and four new selections (LS-1 to LS-4) were determined by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). The oil yield ranged from 0.31% to 1.0% with CPK-25 (1.0%) and LS-2 (0.95%) containing the highest. A total of 66 compounds, constituting 84.6–94.3% of the oils, were identified. The main compounds were geranial (29.9–41.6%), neral (25.8–32.5%), citronellol (0.3–12.8%), geranyl acetate (1.2–8.4%), and geraniol (1.8–8.2%). Of the cultivars, OD-19 (74.1%) had the highest and LS-3 (55.7%) contained the lowest amount of total citral. CKP-2…

0106 biological sciences0301 basic medicinePharmacologyCitronellolGeranyl acetateCitral01 natural scienceslaw.invention03 medical and health scienceschemistry.chemical_compoundHorticulture030104 developmental biologyComplementary and alternative medicinechemistrylawBotanyComposition (visual arts)CultivarGas chromatographyEssential oilGeraniol010606 plant biology & botanyJournal of Herbs, Spices & Medicinal Plants
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NMD-Based Gene Regulation—A Strategy for Fitness Enhancement in Plants?

2019

Abstract Post-transcriptional RNA quality control is a vital issue for all eukaryotes to secure accurate gene expression, both on a qualitative and quantitative level. Among the different mechanisms, nonsense-mediated mRNA decay (NMD) is an essential surveillance system that triggers degradation of both aberrant and physiological transcripts. By targeting a substantial fraction of all transcripts for degradation, including many alternative splicing variants, NMD has a major impact on shaping transcriptomes. Recent progress on the transcriptome-wide profiling and physiological analyses of NMD-deficient plant mutants revealed crucial roles for NMD in gene regulation and environmental response…

0106 biological sciences0301 basic medicinePhysiologyNonsense-mediated decayMutantMRNA DecayPlant ScienceComputational biologyBiology01 natural sciencesTranscriptome03 medical and health sciencesSpecies SpecificityGene Expression Regulation PlantGene expressionPlant Physiological PhenomenaRegulation of gene expressionRNA quality controlGene Expression ProfilingAlternative splicingCell BiologyGeneral MedicinePlantsNonsense Mediated mRNA DecayAlternative Splicing030104 developmental biologyTranscriptome010606 plant biology & botanyPlant and Cell Physiology
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Alternative Splicing of the Basic Helix–Loop–Helix Transcription Factor Gene CmbHLH2 Affects Anthocyanin Biosynthesis in Ray Florets of Chrysanthemum…

2021

Chrysanthemum is an important ornamental crop worldwide. Some white-flowered chrysanthemum cultivars produce red ray florets under natural cultivation conditions, but little is known about how this occurs. We compared the expression of anthocyanin biosynthetic and transcription factor genes between white ray florets and those that turned red based on cultivation conditions to comprehend the underlying mechanism. Significant differences in the expression of CmbHLH2 were detected between the florets of different colors. CmbHLH2 generated two alternatively spliced transcripts, designated CmbHLH2Full and CmbHLH2Short. Compared with CmbHLH2Full, CmbHLH2Short encoded a truncated protein with only…

0106 biological sciences0301 basic medicinechrysanthemumMutantPlant Science01 natural sciencesanthocyaninSB1-1110alternative splicing03 medical and health scienceschemistry.chemical_compoundArabidopsisPigment accumulationOriginal Researchbasic helix–loop–helixbiologyChrysanthemum morifoliumAlternative splicingfood and beveragesPlant culturebiology.organism_classificationCell biology030104 developmental biologychemistryMBW complexAnthocyaninRNA splicingHeterologous expression010606 plant biology & botanyFrontiers in Plant Science
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Arabidopsis RCD1 coordinates chloroplast and mitochondrial functions through interaction with ANAC transcription factors

2019

Reactive oxygen species (ROS)-dependent signaling pathways from chloroplasts and mitochondria merge at the nuclear protein RADICAL-INDUCED CELL DEATH1 (RCD1). RCD1 interacts in vivo and suppresses the activity of the transcription factors ANAC013 and ANAC017, which mediate a ROS-related retrograde signal originating from mitochondrial complex III. Inactivation of RCD1 leads to increased expression of mitochondrial dysfunction stimulon (MDS) genes regulated by ANAC013 and ANAC017. Accumulating MDS gene products, including alternative oxidases (AOXs), affect redox status of the chloroplasts, leading to changes in chloroplast ROS processing and increased protection of photosynthetic apparatus.…

0106 biological sciences0301 basic medicineretrograde signalingChloroplastsArabidopsisPlant BiologyMitochondrion01 natural sciencesElectron Transport Complex IIIGene Expression Regulation PlantArabidopsisOXIDATIVE STRESS-RESPONSETranscriptional regulationCYCLIC ELECTRON FLOWBiology (General)Nuclear proteinANAC transcription factors1183 Plant biology microbiology virologyreactive oxygen speciesbiologyChemistryRETROGRADE REGULATIONGeneral NeuroscienceQRNuclear Proteinsfood and beveragesGeneral MedicinePlants Genetically Modified:Science::Biological sciences [DRNTU]Cell biologyMitochondriaChloroplastviherhiukkasetMedicineSignal transductionmitochondrial functionsResearch ArticleSignal TransductionQH301-705.5SciencemitokondriotGenetics and Molecular BiologyGeneral Biochemistry Genetics and Molecular BiologyPROTEIN COMPLEXESSIGNALING PATHWAYS03 medical and health scienceschloroplastStress PhysiologicalALTERNATIVE OXIDASESkasvitENZYME-ACTIVITIESredox signalingTranscription factorarabidopsis RCD1General Immunology and MicrobiologybiokemiaArabidopsis Proteinsta1182Biology and Life Sciencesbiology.organism_classification030104 developmental biologyCELL-DEATHPLANT-MITOCHONDRIAA. thalianaGeneral BiochemistryRetrograde signalingGENES-ENCODING MITOCHONDRIALproteiinit010606 plant biology & botanyTranscription Factors
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Monitoring of transglutaminase crosslinking reaction by 1H NMR spectroscopy on model substrates

2015

International audience; A new method based on 1H NMR spectroscopy was developed for monitoring transglutaminase crosslinking reaction with model molecules (CBZ-Gln-Gly and N-α-acetyl-lysine). The transglutaminase reaction led to the appearance of new resonances on NMR spectrum as well as significant decrease in others. The new observed resonances, originated from newly formed ɛ-(γ-glutamyl)lysine isopeptide bonds, evidence the enzymatic reaction and allow to quantify the ɛ-(γ-glutamyl)lysine fragment. Moreover, the decrease in resonance intensity, originated from lysine, permit to determine the crosslinking degree. These results obtained by 1H NMR spectroscopy can be used as an alternative …

0106 biological sciences1h nmr spectroscopyTissue transglutaminaseLysineCrosslinking degreePhotochemistrycomplex mixtures01 natural sciences03 medical and health sciencesModel substratesɛ-(γ-glutamyl)-lysineColloid and Surface ChemistryLiquid chromatography–mass spectrometry010608 biotechnologyOrganic chemistryMolecule[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular Biology030304 developmental biologyAlternative methods0303 health sciencesbiologyChemistryResonanceNuclear magnetic resonance spectroscopyMicrobial transglutaminasebiology.proteinColloids and Surfaces A: Physicochemical and Engineering Aspects
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Adaptive strategies of territory formation

2003

How do territorial animals gain ownership of an area? Early modelling has considered the evolution of fighting when the winner can claim the right to the resource. Recently, alternative hypotheses have been offered where repeated interactions lead to division of space through 'nagging' instead of one decisive fight. However, these models assume that animals avoid areas in which they have taken part in aggressive interactions, but do not consider whether avoidance itself is adaptive. We aim to bridge this gap between mechanistic and adaptive explanations, by presenting a game-theory model where individuals choose whether to return to an area after a fight with a specific outcome (win, loss, …

0106 biological sciencesAdaptive strategieseducation.field_of_studyAlternative hypothesismedia_common.quotation_subject05 social sciencesPopulationBiologyTerritoriality010603 evolutionary biology01 natural sciencesOutcome (game theory)NaggingAnimal ecology0501 psychology and cognitive sciencesAnimal Science and Zoology050102 behavioral science & comparative psychologyPositive economicseducationGame theoryEcology Evolution Behavior and Systematicsmedia_commonBehavioral Ecology and Sociobiology
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Historical ethnopharmacology of the herbalists from Krummhübel in the Sudety Mountains (seventeenth to nineteenth century), Silesia

2018

Background Krummhübel (after 1945, Karpacz) in the Sudety Mountains (now SW Poland) was called “the village of pharmacists”. At the end of the seventeenth century, there were 57 households, of which about 40 were inhabited by herbalists. Krummhübel herbalists were the first in the Sudety region who applied medicinal mixtures for the treatment of various diseases (using, among others, plants, oils, minerals and even viper venom) in contrast to previous herbalists who only indicated the use of individual plant species for specific diseases. Riesengebirge (in Polish Karkonosze) potions were sold in Austria, the Czech Republic, Poland and Russia, and some of them could even be purchased in Scan…

0106 biological sciencesCultural StudiesConventional medicineHealth (social science)EthnobotanyHistory 18th Century01 natural sciencesHistory 17th CenturyMedicinal plantsPhytopharmacylcsh:BotanyCardiovascular problemsHumansMedicinal plantsFolk medicineTraditional medicineResearchPlant PartPhytotherapy historyHistory 19th Centurylcsh:Other systems of medicinelcsh:RZ201-999Folk medicine0104 chemical scienceslcsh:QK1-989010404 medicinal & biomolecular chemistryTaxonGeographyComplementary and alternative medicineEthnobotanyMixturesEthnopharmacologyPlant speciesPolandGeneral Agricultural and Biological SciencesPhytotherapy010606 plant biology & botanyJournal of Ethnobiology and Ethnomedicine
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Ethnobotany of dye plants in Southern Italy, Mediterranean Basin: floristic catalog and two centuries of analysis of traditional botanical knowledge …

2020

Abstract Background Since ancient times, man has learned to use plants to obtain natural dyes, but this traditional botanical knowledge (TBK) is eroding. In the late, during, and the early 1800s, there was an increase in research related to dye species, and this allowed the development of industry and economy in rural contexts of Southern Italy. Today, dyes are mainly obtained from synthetic products, and this leads to risks for human health related to pollution. Methods Starting from the literature, three catalogs of the dyeing species (plants, algae, fungi, and lichens) used in the Mediterranean Basin and mainly in Southern Italy have been created. Percentages of parts used and colors ext…

0106 biological sciencesCultural StudiesFloraHealth (social science)LichensEthnobotany01 natural sciencesMediterranean BasinFloristicsEthnobotany Dye plants Mediterranean Basin DatabaseDatabaseHuman healthAlgaelcsh:BotanyHumansLichenColoring AgentsbiologyAgroforestrySettore BIO/02 - Botanica SistematicaResearchFungilcsh:Other systems of medicinePlantsbiology.organism_classificationlcsh:RZ201-9990104 chemical scienceslcsh:QK1-989010404 medicinal & biomolecular chemistryGeographyKnowledgeComplementary and alternative medicineDye plantsItalyEthnobotanySettore BIO/03 - Botanica Ambientale E ApplicataPlant speciesMediterranean BasinGeneral Agricultural and Biological Sciences010606 plant biology & botanyJournal of Ethnobiology and Ethnomedicine
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Ethnobotany of the Aegadian Islands: safeguarding biocultural refugia in the Mediterranean

2021

Abstract Background The Aegadian Islands are located west of Trapani, Sicily. Once the site of bountiful tuna fisheries and fruit orchards (plums, peaches, apricots), grapevines, prickly pears, and grains, the local economy is now based on tourism, and many traditional agricultural and maritime practices have been abandoned. In this study, we aimed to evaluate the state of traditional ecological knowledge (TEK) concerning the use of wild and cultivated plants and fungi for human health, food, maritime, and agricultural purposes on the islands of Levanzo, Favignana, and Marettimo and compare present-day practices with those documented in the past. Methods In-depth semi-structured interviews …

0106 biological sciencesCultural StudiesThe MediterraneanFloraHealth (social science)Artemisia arborescensBiocultural diversityPopulationBiodiversityEthnobotanyPleurotus01 natural sciencesPleurotus eryngiiOther systems of medicineAgave sisalana; Artemisia arborescens; Glaucium flavum; Medicinal plants; Pleurotus eryngii; Ruta chalepensis; The MediterraneanAgaveMedicinal plantsPapaveraceaeHumansTraditional knowledgeeducationAgave sisalanaSicilyIslandseducation.field_of_studyCultivated plant taxonomyPlants MedicinalAgroforestrySettore BIO/02 - Botanica SistematicaResearchBotanyRuta chalepensisGlaucium flavum0104 chemical sciences010404 medicinal & biomolecular chemistryGeographyHerbariumKnowledgeComplementary and alternative medicineArtemisiaRefugiumAgave sisalana Artemisia arborescens Glaucium flavum Medicinal plants Pleurotus eryngii Ruta chalepensis The MediterraneanEthnobotanyQK1-989General Agricultural and Biological SciencesRZ201-999010606 plant biology & botanyJournal of Ethnobiology and Ethnomedicine
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