Search results for "Amfepramone"
showing 2 items of 2 documents
Screening of pharmacologic adulterant classes in herbal formulations using voltammetry of microparticles.
2013
A solid state electrochemical method for screening different families of adulterant chemicals illegally added to commercial phytotherapuetic formulations is described. The proposed method, based on the voltammetry of microparticles approach, permits a fast and sensitive way to distinguish between anorexics (amfepramone, fenproporex, sibutramine), benzozodiazepinic anxiolytics (clonazepam, flurazepam, alprazolam, midazolam, medazepam, chlordiazepoxide, diazepam), antidepressants (bupropione, fluoxetine, sertraline, paroxetine), diuretics (hydrochlorothiazide, furosemide, chlortalidone, amiloride, spironolactone), and hypoglycemics (glimepiride, chlorpropamide, glibenclamide) based on charact…
In situ derivatization for double confirmation of 2C–C in oral fluids by ion mobility spectrometry
2017
Ion mobility spectrometry (IMS) is a powerful tool to carry out quick and sensitive detection of illicit activities and has been employed for the determination of the psychedelic drug 2,5-dimethoxy-4 chlorophenethylamine (2C–C) in oral fluid samples. Saliva samples were extracted with chloroform and analysed by IMS reaching a limit of detection (LOD) of 14 μg L−1. Nevertheless, IMS has a scarce resolution and selectivity of the method can be often compromised by the presence of potential interferents with similar molecular weights and drift times. Thus, a rapid and in situ derivatization with acetone, to form the corresponding imine, has been proposed in the present study to confirm the pre…