Search results for "Anal canal"

showing 10 items of 90 documents

Transanal Endoscopic Microsurgery for T1 and T2 Rectal Cancers: A Meta–Analysis and Meta-Regression Analysis of Outcomes

2011

The objective of this study is to assess transanal endoscopic microsurgery (TEM) as a surgical strategy for stage I rectal cancer. The literature lacks level I and level II evidence of the oncologic competence of TEM. Three randomized controlled, one prospective, and seven retrospective comparative studies were evaluated. End-points included perioperative outcomes, margin involvement, disease-free and overall survival, and recurrence. The number of patients with major (odds ratio (OR) = 0.24,95% confidence interval (CI) 0.07–0.91) and overall postoperative complications (OR = 0.16, 95% CI 0.06-0.38) were significantly lower in TEM. The disease-free survival was higher in standard resection…

Transanal ExcisionMicrosurgerymedicine.medical_specialtyRectal Neoplasmsbusiness.industrymedicine.medical_treatmentAnal CanalGeneral MedicineOdds ratioPerioperativeMicrosurgeryDisease-Free SurvivalConfidence intervalSurgeryStage I rectal cancerTreatment OutcomeMeta-analysisOdds RatioHumansRegression AnalysisMedicineMeta-regressionNeoplasm Recurrence LocalbusinessNeoplasm StagingThe American Surgeon
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Immunohistochemical localization of the pro-peptide processing enzymes PC1/PC3 and PC2 in the human anal canal.

1997

Abstract HORsch, D., R. Day, N. G. Seidah, E. Weihe and M. K.-H. SchAFer. Immunohistochemical localization of the pro-peptide processing enzymes PC1/PC3 and PC2 in the human anal canal. Peptides 18(5) 755–760, 1997.—The distribution of prohormone/pro-peptide convertases PC1/PC3 and PC2 was investigated in the human anal canal by immunohistochemistry. Both prohormone convertases exhibited region-specific distribution patterns and were observed in neural and neuroendocrine cells and in nonneuroendocrine cellular elements. PC1/PC3 immunoreactivity was present in enteric neurons, subsets of nerve fibers, and neuroendocrine cells, and also in epithelial cells like intestinal stem cells, and a su…

endocrine systemPathologymedicine.medical_specialtyPhysiologyProhormoneNeuropeptideRectumAnal CanalBiologyBiochemistryImmunoenzyme TechniquesCellular and Molecular NeuroscienceEndocrinologymedicineChromograninsAspartic Acid EndopeptidasesHumansSubtilisinsAnal Transitional ZoneNeuronsNeuropeptidesAnal canalNeurosecretory SystemsEpitheliumNeoplasm Proteinsmedicine.anatomical_structureProprotein Convertase 2Fluorescent Antibody Technique DirectChromogranin AProprotein ConvertasesStem cellImmunostainingmedicine.drugPeptides
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Technique for Performing Rectoscopy

1979

After positioning of the patient (Figs. 1 and 11), the instrument is introduced into the anus. The anal canal runs diagonally toward the navel. This distance must be passed blindly. The instrument is therefore guided through this area with the help of the obturator, which is promptly removed after passage of the instrument through the anal canal.

medicine.anatomical_structureRectal ampullabusiness.industrymedicineNavelAnatomyAnal canalRectosigmoid junctionAnusbusinessBiopsy forceps
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Digital Rectal Examination (Fig. 2a and 2b)

1979

During examination of the anal region and before doing the rectal examination, the hand is protected by a plastic glove. A number of disposable gloves of varying strengths are on the market. One may additionally use a finger cot on the forefinger, which is removed after the examination. The examination can also be done using a finger cot alone with the finger stuck through a piece of gauze that protects the rest of the hand. Right-handed examiners often elect to use the forefinger of the left hand for the rectal examination and keep the right hand uncontaminated for handling instruments.

medicine.medical_specialtyAnal fissuremedicine.diagnostic_testbusiness.industryAnal RegionRectal examinationAnal canalmedicine.diseaseSurgerybody regionsRectal prolapsemedicine.anatomical_structureFINGER COTInternal HemorrhoidmedicinebusinessRest (music)
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Surgical anatomy of the deep postanal space and the re-modified Hanley procedure - a video vignette.

2018

medicine.medical_specialtyAnus DiseasesDeep postanal spacebusiness.industryGeneral surgeryGastroenterologyMEDLINEAnal CanalVideo-Audio MediaPerineumAbscess03 medical and health sciences0302 clinical medicineVignetteSurgical anatomyCadaver030220 oncology & carcinogenesisCadaverMedicineHumansRectal Fistula030211 gastroenterology & hepatologyAnatomic Landmarksbusiness
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An 'easy' method to understand perianal sepsis - a video vignette.

2019

medicine.medical_specialtyAnus DiseasesPerianal sepsisbusiness.industryGastroenterologyMEDLINEAnal CanalPerineumAbscessVignetteSepsismedicineCadaverHumansFemaleAnatomic LandmarksIntensive care medicinebusiness
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Fisurectomy and anoplasty with botulinum toxin injection in patients with chronic anal posterior fissure with hypertonia: a long-term evaluation.

2020

AbstractChronic anal fissure’s (CAF) etiopathogenesis remain unclear. CAF of the posterior commissure (CAPF) are often characterized by internal anal sphincter (IAS) hypertonia. The treatment of this disease aimed to reduce IAS hypertonia. Due to the high rate of anal incontinence after LIS, the employment of sphincter preserving surgical techniques associated to pharmacological sphincterotomy appears more sensible. The aim of our study is to evaluate the long-term results of fissurectomy and anoplasty with V–Y cutaneous flap advancement associated to 30 UI of botulinum toxin injection for CAPF with IAS hypertonia. We enrolled 45 patients undergone to fissurectomy and anoplasty with V–Y cut…

medicine.medical_specialtyBotulinum ToxinsUltrasound waveAnal CanalBotulinum toxin injectionInternal anal sphincterFissurectomyBotulinum toxinSphincterotomyMuscle HypertoniamedicineHumansIn patientProspective StudiesAnal fissurebusiness.industryAnoplastymedicine.diseaseBotulinum toxinSurgerymedicine.anatomical_structureTreatment OutcomeAnal fissure Anoplasty Botulinum toxin Fissurectomy Proctology SphincterotomyChronic DiseaseSphincterHypertoniaSurgeryOriginal ArticleFissure in Anomedicine.symptomProctologyAnal fissurebusinessmedicine.drugUpdates in surgery
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Role of fluorine 18 fluorodeoxyglucose positron emission tomography/computed tomography in gastrointestinal cancers

2015

AbstractFluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) has become a routine imaging modality for many malignancies and its use is currently increasing. In the present review article, we will summarize the evidence for FDG-PET/CT use in digestive cancers (excluding neuroendocrine tumours), and review the existing recommendations. While PET/CT is nowadays considered to be an important tool in the initial workup of oesophageal and anal cancers, new data are emerging regarding its use in assessing therapeutic efficacy, radiotherapy treatment planning, and detection of recurrence in case of isolated tumour marker elevation. Moreover, PET/CT may help …

medicine.medical_specialtyColorectal cancerColonoscopyDigestive System NeoplasmsMultimodal ImagingPatient Care PlanningFluorodeoxyglucose positron emission tomographyFluorodeoxyglucose F18Pancreatic cancerHumansMedicinePositron Emission Tomography-Computed TomographyFluorine-18-fluorodeoxyglucoseHepatologymedicine.diagnostic_testbusiness.industryOesophageal cancerGastroenterologyPancreatic cancerRadiotherapy treatment planningPrognosismedicine.diseaseColorectal cancerFDG-PET/CTAnal canal cancerReview articleNeuroendocrine TumorsPositron-Emission TomographyPractice Guidelines as TopicRadiologyNeoplasm Recurrence LocalRadiopharmaceuticalsTomography X-Ray ComputedbusinessDigestive and Liver Disease
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Management of rectal cancer in France in a well-defined population.

2014

Objective The aim of this study was to draw a picture of diagnostic assessment and patterns of care for rectal cancer in France using population-based registries data. Methods The study included a random sample of 669 cases of rectal cancers diagnosed in 2005. Results Diagnostic assessment was performed by colonoscopy in 91.4% of the cases. An abdominal computed tomography was performed in 59.4% of the cases and chest computed tomography in 47.8%. An R0 resection was performed in 65.8% of cases and an R1/R2 resection in 16.1%. A rectal endosocography was performed in 40.4% and MRI in 10.4%. The sphincter was preserved in 73.6% of patients aged younger than 75 years of age and in 62.5% of th…

medicine.medical_specialtyColorectal cancermedicine.medical_treatmentPopulationColonoscopyAnal CanalPreoperative carePreoperative CaremedicineHumansRegistriesStage (cooking)educationAgedNeoplasm Stagingeducation.field_of_studyHepatologymedicine.diagnostic_testbusiness.industryRectal NeoplasmsPalliative CareGastroenterologyAge FactorsChemoradiotherapy AdjuvantColonoscopymedicine.diseaseRadiation therapymedicine.anatomical_structureSphincterRadiologyFrancebusinessTomography X-Ray ComputedChemoradiotherapyEuropean journal of gastroenterologyhepatology
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Performing, Analyzing, and Interpreting HRAM and HDAM Recordings

2020

Anorectal manometry is one of the most widely performed tests for the assessment of anal sphincter function and anorectal coordination. Nowadays high resolution (HRAM) and high definition anorectal manometry (HDAM) are available, instead of the water-perfused system. The ability to visualize the anorectum as a dynamic structure during test maneuvers should intuitively allow for a better appreciation of the normal physiology and hopefully enhance our understanding of the pathophysiology of defecatory dysfunctions. Even if the anorectal manometry protocols can vary by centers, the procedure must include an assessment of rectoanal pressure and anal canal length at rest, cough reflex test, rect…

medicine.medical_specialtyEuropean levelbusiness.industrymedia_common.quotation_subjectAnorectal manometryHigh resolutionAnal canalPhysical medicine and rehabilitationmedicine.anatomical_structureMedicineHigh definitionRectal sensationbusinessAnal sphincterNormalitymedia_common
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