Search results for "Anatomia"
showing 10 items of 1108 documents
Younger is better? Isolation and phenotypical characterization of mesenchymal stem cells from the Wharton's jelly of pre-term human umbilical cords
2014
Levels of circulating gelatinases and proteomic correlations in breast cancer patients.
2008
Intrasession and Intersession Repeatability of a new PCT-200 Corneal Topographer on Calibrated Steel Surfaces and Healthy Eyes
2010
PURPOSE: To assess intrasession and intersession repeatability of a new tilted-cone, Placido-disc based corneal topographer (PCT-200, Optopol Tech., Poland) on calibrated steel surfaces and healthy human eyes. METHODS: Five repeated measures of surface topography were obtained on a set of four different calibrated steel spherical surfaces and on a sample 30 healthy human eyes in each of two sessions. Variance of apical radius, eccentricity and Fourier Indices was assessed both within and between sessions using analysis of variance (ANOVA), paired samples t-test and intraclass correlation coefficients (ICC). RESULTS: Repeated measurements on calibrated steel surfaces and human eye sample of …
From Dysbiosis to Neurodegenerative Diseases through Different Communication Pathways: An Overview
2023
The microbiome research field has rapidly evolved over the last few decades, becoming a major topic of scientific and public interest. The gut microbiota (GM) is the microbial population living in the gut. The GM has many functions, such as maintaining gut homeostasis and host health, providing defense against enteric pathogens, and involvement in immune system development. Several studies have shown that GM is implicated in dysbiosis and is presumed to contribute to neurodegeneration. This review focuses mainly on describing the connection between the intestinal microbiome alterations (dysbiosis) and the onset of neurodegenerative diseases to explore the mechanisms that link the GM to nerv…
The many lives of Hsp10: From Early Pregnancy Factor to Potential Antitumoral Agent. New Proteomic Data and a Review of the Literature Focusing on It…
2008
Wharton’s jelly mesenchymal stem cells differentiation into hepatocyte-like cells: functional characterization and expression of immunomodulatory mol…
2015
Mesenchymal stem cells derived from Wharton’s jelly (WJ-MSCs) recently emerged as promising tools for cellular therapy due to their ability to differentiate into diverse cell types and their immunomodulatory features. Little is known on the expression of immunomodulatory molecules in mature cells differentiated from WJ-MSCs, therefore we aimed to characterize the extent of maintenance of the naive traits of these cells also in a highly specialized differentiated counterpart. WJ-MSCs were differentiated into hepatocyte-like cells (HLCs) with a four weeks protocol. RT-PCR, flow cytometry, IHC and ICC were performed to assess expression of key markers in both undifferentiated and differentiate…
The Ferroxidase Hephaestin in Lung Cancer: Pathological Significance and Prognostic Value
2021
AbstractIron is a fundamental nutrient utilized by living cells to support several key cellular processes. Despite its paramount role to sustain cell survival, excess of labile iron availability can inflict severe cell damage via reactive oxygen species generation which, in turn, can promote neoplastic transformation. The lung is particularly sensitive to iron-induced oxidative stress, given the high oxygen tensions herein present. Moreover, cigarette smoke as well as air pollution particulate can function as vehicles of iron supply, leading to an iron dysregulation condition shown to be crucial in the pathogenesis of several respiratory diseases including lung cancer. Hephaestin (HEPH) bel…