Search results for "Anatomia"
showing 10 items of 1108 documents
JAHA, a novel histone deacetylase inhibitor: cytotoxic effect on triple-negative breast cancer cells
2013
Morphological and biomolecular charachteristics of subcentimetric invasive breast carcinomas: a sicilian multicentric retrospective analysis
2010
Heat Shock Proteins in Multiple Sclerosis Pathogenesis: Friend or Foe?
2015
Multiple Sclerosis is a complex chronic inflammatory, neurodegenerative disease conditioned by genetic, epigenetic and environmental factors. Main pathological features of MS include areas of focal demyelination of white matter characterized by gliosis, neuron and oligodendrocyte loss. Neurodegenerative as well as immune-mediated processes play a role in the pathogenesis of this disease. One of these immunogenic factors could be represented by the heat shock proteins. HSP exhibit cytoprotective and cytostimulatory effects due to their molecular chaperones role, in many brain model misfolding diseases such as Alzheimer’s and Parkinson’s diseases, whereas still no unambiguous results have bee…
Potential role of p53 protein as a novel biomarker of sperm quality, able to predict the success of ART techniques. EcoFoodFertility Project
2018
Introduction: Protein p53 is well known as “The guardian of genome”; it changes its concentration in human spermatozoa DNAin relation to the damage of the latter. It has been suggested thatthe role of the p53 ancestral gene was to ensure the integrity ofthe genomic germline and the fidelity of the evelopment process.The aim of this study is to evaluate if different concentrations of p53 protein in human spermatozoa could influence embryo quality and pregnancy rate and possibly representing a potential predictive marker of sperm quality for successful fertilization .Methods: From July 2013 to June 2017 we have examinatedretrospectively 79 couples with 2-5 years of infertility history.Males had…
Author Correction: Tissue fluidification promotes a cGAS–STING cytosolic DNA response in invasive breast cancer (Nature Materials, (2022), 10.1038/s4…
2023
In the version of this article initially published, the first name of Flora Ascione was listed as “Floriana”; the error has been corrected in the HTML and PDF versions of the article.
Determinazione del tempo di permanenza in acqua in base allo sviluppo di mitili impiantatisi su cadavere scheletrizzato e saponificato.
2010
C10) DETERMINAZIONE DEL TEMPO DI PERMANENZA IN ACQUA IN BASE ALLO SVILUPPO DI MITILI IMPIANTATISI SU CADAVERE SCHELETRIZZATO E SAPONIFICATO L. Milone (*) – S. Procaccianti (*) – M. Grillo (*) – B. Salerno (**) - E. Carra (**) (*) Dipartimento Di Biopatologia E Biotecnologie Mediche E Forensi – Sezione Di Medicina Legale – Liviomilone@Virgilio.It - (**) Dipartimento Di Biologia Cellulare E Dello Sviluppo – Universita’ Degli Studi Di Palermo Introduzione: La valutazione tanatocronologica di cadaveri in avanzato stato di putrefazione, dovuto alla lunga permanenza in acqua salata, pone non pochi problemi al patologo forense che deve risalire all’epoca del decesso, che spesso viene indicata solt…
Cadmium effect on gene expression by MDA-MB231 breast cancer cells: evidence for down-regulation of AEG-1
2006
Effect of cadmium and manganese on gene expression and proliferative/invasive ability of tumoral and immortalized epithelial cells form the human bre…
2008
Apoptosis during early development of sea urchin.
2008
Apoptosis is a genetic program of cell death that eliminates superfluous or compromised cells during development and adult life of many organisms. In sea urchin embryos, apoptosis is not only a physiological event during larval metamorphosis, but also a process induced by cadmium accumulation or other stressor like TPA (12-O-tetradecanoylphorbol-13-acetate) followed by an increase of temperature to 31°C. Apoptosis is a highly conserved process usually operated by a proteolytic cascade that involves caspase activation by two different pathways: extrinsic and intrinsic. The first one involves membrane death receptors, while the second involves mitochondria. In this work we analyzed the possib…