Search results for "Anatomia"

In vitro and in vivo detection of end-products of MPO-driven oxidative and nitrosative stress in human endocardial endothelial cells from patients af…

2008

Effect of environmental stress on sea urchin embryos and larvae: from developmental to molecular biology analyses

2010

Extracellulare membrane vesicles as vehicles for cell-to-cell and cell-to-extracellular matrix functional interactions

2012

Effect of extracellular vesicles from CSF of multiple sclerosis patients and healthy controls on astrocytes in culture

2017

INTRODUCTION Secretion of extracellular vesicles (EVs) and EV-mediated exchange of molecules among brain cells, under physiological conditions, has been described years ago. At the same time, ability of EVs to transfer proteins and nucleic acids to the surrounding cells, thus modifying their phenotypes, has been clearly demonstrated for tumor cells of different origins, including brain cancers. More recently, involvement of EVs in pathological processes affecting the Central Nervous System (CNS), and their capacity of transferring damaging cargoes have been also suggested. To explore these functions, we exposed primary cultures of astrocytes to EVs isolated from cerebral spinal fluid (CSF) …

Paracrine roles of extracellular vesicles released by mouse mesoangioblasts

2017

Extracellular vesicles (EV) represent an important mediator of cell-to-cell communication and are involved in both autocrine and paracrine signaling, with a critical role in a number of physiological and pathological conditions.1 The bioactive molecules contained within EV simultaneously activate several different pathways resulting in the synergistic stimulation of target cells. The discovery and characterization of EV have added a novel understanding to regenerative medicine, namely the finding that stem cells are an abundant source of EV.1-2 A6 mouse mesoangioblasts, vessel-associated multipotent progenitor stem cells that are capable of differentiating into different mesodermal cell typ…

Low frequencies noise effects on behaviour of Sparus aurata juveniles

2019

Human activities in the oceans, such as marine traffic and Deep Sea Mining (DSM), are increasing in the last years (Ross 2005; Calvo et al 2016). Underwater noise in the oceans, especially at lower frequencies, is mainly produced by marine traffic and DSM could increase this noise in the next future. Marine Strategy Framework Directive promotes the achievement of a good quality environmental status and aims to monitor “continuous low frequency sound” trend in the ambient noise level within the 1/3 octave bands centred at 63 and 125 Hz. The aim of this study is to evaluate the behavioural changes of Sparus aurata juveniles exposed to a four different acoustic signals in a tank. The emitted s…

Anthropic impact, bioactive molecules, sustainable development, my keyword? Biodiversity!

2023

Biodiversity is my main research focus and that of my research group. We study a range of different aspects concerning biodiversity, such as the impact anthropic activities have on biodiversity and how to improve its preservation, its use as a valuable resource for the extraction of bioactive molecules, and the study of its distribution. The research group has over twenty years of experience in the study of zoology, and, more in particular, the immune and behavioural responses of aquatic invertebrates and fish. For many years, the group has observed the effects of various anthropogenic activities, such as the acoustic and chemical impacts on the physiological and behavioral responses of inv…

EFFECT OF SUBMARINE ACOUSTIC NOISE IN JUVENILE SEA BREAM (SPARUS AURATA) AND MUSSELS (MYTILUS GALLOPROVINCIALIS)

2018

The earth’ resources are running out, the population will increase and further sources will be needed. These, were found in the deep ocean. To date the mining activities (Deep Sea Mining, DSM) they have not started. One impact of DSM could be underwater noise. Considering the noise frequencies of anthropic activities in the ocean, and the European directive on underwater noise control, we stressed the animals with four acoustic 1/3 band noises around: 63 Hz, 125 Hz, 500 Hz, 1kHz. We study the effects on Sparus aurata juveniles, and on Mytilus galloprovincialis. We will analyse behavioural., molecular and biochemical responses Los recursos de la tierra se están agotando, la población aumenta…

Nationwide interobserver variation in the diagnosis of follicular lymphoma: a report from the pathologists of GISL (Gruppo Italiano Studio Linfomi)

2005

Interobserver variability may occur in FL diagnosis, even when the diagnosis is performed by expert haematopathologists. Very limited informations are currently available on the reliability of FL diagnosis performed in laboratories on a national scale, where the lymphoma diagnosis is not always carried on by expert haematopathologists. In this study, the reproducibility of the FL diagnosis and related grading system was tested by a group of pathologists members of the Gruppo Italiano Studio Linfomi (GISL).

Agujero Transverso Bipartito en población rural del siglo XVII y en poblablación actual

2015

INTRODUCCIÓN La columna cervical se diferencia claramente de la región torácica y lumbar, tanto en su anatomía como en su biomecánica (Kapandji IA, 2007). Asimismo, la región cervical debe conciliar su gran movilidad con su papel clave en el paso de estructuras vasculares y nerviosas relacionadas con la región craneal (Gray H, 1989; Das, S et al, 2005; Drake RL et al, 2010; White TD et al, 2011). En este sentido, entre los rasgos anatómicos distintivos de las vértebras cervicales, se encuentra un orificio en las apófisis transversas, denominado foramen transverso, a través del cual asciende la arteria vertebral (White TD et al, 2011; Moore KL et al, 2013). Con respecto a los diámetros anter…