Search results for "Anatomic"

showing 10 items of 16742 documents

Bindungsstudien mit Ulex Europaeus Agglutinin I (UEA-I) am Gefäßendothel der Synovialmembran*

2008

The lectin binding sites of the synovium of patients with rheumatoid arthritis and osteoarthritis were investigated. It was shown that Ulex europaeus agglutinin is a constant marker of the vascular endothelium and is not induced during the course of inflammatory process in rheumatoid arthritis.

musculoskeletal diseasesPathologymedicine.medical_specialtybiologyEndotheliumChemistryArthritisOsteoarthritismedicine.diseasebiology.organism_classificationUlex europaeusVascular endotheliumAgglutininmedicine.anatomical_structureRheumatoid arthritisLectin bindingImmunologymedicineOrthopedics and Sports MedicineSurgeryskin and connective tissue diseasesZeitschrift für Orthopädie und ihre Grenzgebiete
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Ultrastructural causes of rupture of hand tendons in patients with rheumatoid arthritis. A transmission and scanning electron microscopic study.

1993

To identify the cause of rupture of hand tendons in patients with rheumatoid arthritis, we studied the underlying ultrastructural changes of the collagenous fibril systems. Samples of the flexor digitorum superficialis (n = 12) and the extensor digitorum communis (n = 20) were taken during tenosynovectomy. Tendons dissected at necropsy (n = 30) served as controls. Specimens were analysed by transmission and scanning electron microscopy. Interfibrillar dysplastic fibrils, "Luse bodies", and intracellular collagen were found in rheumatoid tissues. The diameters of collagen fibrils were significantly reduced compared with the control group (p0.01). The duration of the disease usually correlate…

musculoskeletal diseasesPathologymedicine.medical_specialtymedicine.medical_treatmentSynovectomyFibrillaw.inventionArthritis RheumatoidTendonslawmedicineHumansRupture Spontaneousbusiness.industryGeneral MedicineAnatomyMiddle Agedmusculoskeletal systemmedicine.diseaseHandTendonMicroscopy Electronmedicine.anatomical_structureRheumatoid arthritisUltrastructureMicroscopy Electron ScanningUpper limbCollagenElectron microscopebusinessExtensor Digitorum CommunisScandinavian journal of plastic and reconstructive surgery and hand surgery
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Comparison between the directly measured achilles tendon force and the tendon force calculated from the ankle joint moment during vertical jumps.

1988

Summary The purpose of this study was to compare the relationship between the achilles tendon force and the tendon force estimated from the ankle joint moment (EATF) during vertical jump. A healthy male subject performed the following jumps on the force platform: (a) maximal vertical jump from a squat position without counter-movement; (b) maximal vertical jump from an erect standing position with a preliminary counter-movement; (c) repetitive submaximal hopping on the spot with preferred frequency. The achilles tendon force was measured directly with an implanted tendon transducer in all jumping conditions. In addition the joint moment obtained from the film and ground reaction force was u…

musculoskeletal diseasesPhysicsAchilles tendonBiophysicsMechanicsAnatomymusculoskeletal systemmedicine.disease_causeTendonInverse dynamicsVertical jumpJumpingmedicine.anatomical_structuremedicineOrthopedics and Sports MedicineForce platformAnkleGround reaction forceClinical biomechanics (Bristol, Avon)
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Viewpoint: On the hysteresis in the human Achilles tendon.

2012

This viewpoint was stimulated by two observations: 1) the statistical skewness whereby numerous articles have reported tendon stiffness and Young9s modulus, but far fewer have reported tendon hysteresis; 2) in vivo human studies seem very often to report hysteresis values greater than 10%, suggesting either that there are methodological differences between human and animal studies, or that human tendons have a much poorer capacity to store and reutilize elastic energy. In this article we focus on the healthy human Achilles/gastrocnemius tendon (AT) since it has an important locomotor function and clearly a low AT hysteresis would allow elastic recoil for efficient locomotion. We discuss tha…

musculoskeletal diseasesPhysicsAchilles tendonHuman studiesPhysiologyTendon stiffnessViscosityAnatomymusculoskeletal systemAchilles TendonTendonElastic recoilmedicine.anatomical_structureHysteresis (economics)Physiology (medical)Elastic ModulusmedicineHumansGastrocnemius tendonBiomarkersLocomotionBiomedical engineeringJournal of applied physiology (Bethesda, Md. : 1985)
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Sicilian pistachio (Pistacia vera L.) nut inhibits expression and release of inflammatory mediators and reverts the increase of paracellular permeabi…

2014

Background Dietary approaches to control inflammatory bowel diseases (IBD) may include proanthocyanidin-rich foods. Our previous research showed that a hydrophilic extract from Sicilian pistachio nut (HPE) contains sub- stantial amounts of proanthocyanidins and possesses anti- inflammatory activities. Purpose We studied the effects of HPE and of its poly- meric proanthocyanidin fraction (PPF) in a cell model that simulated some conditions of IBD, consisting of interleukin (IL)-1b-stimulated Caco-2 cells. Methods HPE was prepared by Pistacia vera L. nuts, and PPF was isolated from HPE by adsorbance chromatogra- phy. Proanthocyanidins were quantified as anthocyanidins after acidic hydrolysis.…

musculoskeletal diseasesPistachio nut Inflammation Intestinal epithelium Polyphenols Proanthocyanidinscongenital hereditary and neonatal diseases and abnormalitiesCellInterleukin-1betaAnti-Inflammatory AgentsMedicine (miscellaneous)BiologyPharmacologyPermeabilityCell membraneSettore BIO/10 - BiochimicamedicineHumansNutsProanthocyanidinsViability assayIntestinal MucosaCell ProliferationNutrition and DieteticsPistaciaInterleukin-6Interleukin-8NF-kappa BEpithelial Cellsbiology.organism_classificationIntestinal epitheliumIntestinesmedicine.anatomical_structureProanthocyanidinBiochemistryCaco-2Cyclooxygenase 2Paracellular transportPistaciaCaco-2 Cells
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Profilin 1 Negatively Regulates Osteoclast Migration in Postnatal Skeletal Growth, Remodeling, and Homeostasis in Mice

2019

Profilin 1 (Pfn1), a regulator of actin polymerization, controls cell movement in a context-dependent manner. Pfn1 supports the locomotion of most adherent cells by assisting actin-filament elongation, as has been shown in skeletal progenitor cells in our previous study. However, because Pfn1 has also been known to inhibit migration of certain cells, including T cells, by suppressing branched-end elongation of actin filaments, we hypothesized that its roles in osteoclasts may be different from that of osteoblasts. By investigating the osteoclasts in culture, we first verified that Pfn1-knockdown (KD) enhances bone resorption in preosteoclastic RAW264.7 cells, despite having a comparable num…

musculoskeletal diseasesPodosomeChemistryEndocrinology Diabetes and MetabolismMotilityMetaphysisBone resorptionCell biologymedicine.anatomical_structureOsteoclastmedicineOrthopedics and Sports MedicineBone marrowProgenitor cellActinJBMR Plus
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The Shoulder Girdle

2000

The shoulder girdle is an anatomically complex structure consisting of the scapula, clavicula, proximal humerus, and their articular connections. The wide range of motion is provided by the glenohumeral joint and the two shoulder girdle joints, the acromioclavicular and sternoclavicular joints.

musculoskeletal diseasesProximal humerusbusiness.industryAnatomymusculoskeletal systemmedicine.anatomical_structureScapulaShoulder girdlemedicineRotator cuffRange of motionbusinesshuman activitiesJoint (geology)
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The radial artery is larger than the ulnar.

2003

The radial artery is presently widely used as a bypass graft for coronary artery reconstruction. However, the traditional opinion that the ulnar artery is the larger forearm artery has been questioned.The internal diameters of the radial and ulnar arteries were measured at the wrist in postmortem angiograms of 24 cadavers. Differences in mean values of variables between ulnar and radial arteries were analyzed using the Wilcoxon test.The mean diameter of the radial artery was 28% larger than that of the ulnar artery in the right arm (p0.001) and 26% larger in the left arm (p0.001). In the right arm the radial artery was dominant in 20 of 24 cadavers (83%), the ulnar artery in 3 of 24 (13%), …

musculoskeletal diseasesPulmonary and Respiratory Medicinemedicine.medical_specialtyWristUlnar ArteryForearmCadaverReference Valuesmedicine.arteryInternal medicinemedicineHumansDerivationRadial arteryCoronary Artery BypassMathematical ComputingUlnar arterybusiness.industryCoronary artery reconstructionAnatomyArteriesWristbody regionsRadiographymedicine.anatomical_structureRadial ArteryCardiologySurgeryCardiology and Cardiovascular MedicinebusinessArteryThe Annals of thoracic surgery
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AB1197 Changes in Lumbar Spinopelvic Pattern of Movement Influence the Flexion Relaxation of the Erector Spinae

2015

Background In healthy subjects, the erector spinae muscles (ES) exhibits a relaxation of its electrical activity when the trunk is nearby its full flexion. Objectives To find out the influence of exhibiting a lumbar spine or a pelvis dominant pattern of movement during trunk flexion from upright position on the appearance of the myoelectric relaxation of the erector spinae. In healthy subjects, the erector spinae muscles (ES) exhibits a relaxation of its electrical activity when the trunk is nearby its full flexion. Objectives To find out the influence of exhibiting a lumbar spine or a pelvis dominant pattern of movement during trunk flexion from upright position on the appearance of the my…

musculoskeletal diseasesRelaxation (psychology)business.industryImmunologyAnatomyFlexion relaxationmusculoskeletal systemTrunkGeneral Biochemistry Genetics and Molecular BiologySagittal planeLumbarmedicine.anatomical_structureRheumatologyErector spinae musclesImmunology and AllergyMedicineLumbar spinebusinessPelvisAnnals of the Rheumatic Diseases
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Screw‐in‐screw fixation of fragility sacrum fractures provides high stability without loosening—biomechanical evaluation of a new concept

2020

Surgical treatment of fragility sacrum fractures with percutaneous sacroiliac (SI) screw fixation is associated with high failure rates. Turn-out is detected in up to 20% of the patients. The aim of this study was to evaluate a new screw-in-screw implant prototype for fragility sacrum fracture fixation. Twenty-seven artificial hemipelvises were assigned to three groups (n = 9) for instrumentation of an SI screw, the new screw-in-screw implant prototype, ora transsacral screw. Before implantation, a vertical osteotomy was set in zone 1 after Denis. All specimens were biomechanically tested to failure in upright position. Validated setup and test protocol were used for complex axial and torsi…

musculoskeletal diseasesSacrumMaterials sciencePercutaneousmedicine.medical_treatmentBone Screws0206 medical engineering02 engineering and technologyOsteotomyPelvisScrew fixationFracture Fixation InternalFractures Bone03 medical and health sciences0302 clinical medicineFragilitymedicineHumansOrthopedics and Sports MedicinePelvis030203 arthritis & rheumatologyOrthodonticsX-Raysequipment and suppliesmusculoskeletal systemSacrum020601 biomedical engineeringBiomechanical PhenomenaOsteotomyRadiographysurgical procedures operativemedicine.anatomical_structureSpinal FracturesStress MechanicalImplantTest protocolJournal of Orthopaedic Research
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