Search results for "Anatomical structures"
showing 6 items of 16 documents
Therapeutic targets for overactive bladder other than smooth muscle
2015
For a long time, our concepts of regulation of urinary bladder function in health and disease as well as of the target structures of therapeutics have focused on detrusor smooth muscle cells. However, other structures including urothelium, afferent nerves and bladder blood vessels may also be important in pathophysiology and its treatment.Based on a selective review of literature, we discuss the role of urothelium, afferent nerve fibers and bladder blood vessels in bladder pathophysiology and as targets for treatment.There is solid evidence now that multiple anatomical structures within the urinary bladder contribute to the regulation of its function and hence may be targets for established…
Combination prosthetic design providing a superior retention for mid-facial defect rehabilitation: A Case Report
2017
Large maxillofacial defects from malignant tumor treatment are rarely rehabilitated by surgical reconstruction alone. Ameloblastic carcinoma, a rare aggressive odontogenic malignant tumor, requires wide surgical excision to gain a tumor-free margin. In the post-surgical defect, prosthetic rehabilitation is the treatment of choice to restore function and esthetics. Moreover, an intra-oral prosthesis such as an obturator restores speech, mastication and deglutition. Retention of the obturator is a major problem while rehabilitating large defects. The existing anatomical structures from the defect with the help of magnet attachments are suitable to enhance retention, stability and support of t…
Impact of Sex Differences and Diabetes on Coronary Atherosclerosis and Ischemic Heart Disease
2018
Cardiovascular diseases (CVD) including coronary artery disease (CAD) and ischemic heart disease (IHD) are the main cause of mortality in industrialized countries. Although it is well known that there is a difference in the risk of these diseases in women and men, current therapy does not consider the sexual dimorphism; i.e., differences in anatomical structures and metabolism of tissues. Here, we discuss how genetic, epigenetic, hormonal, cellular or molecular factors may explain the different CVD risk, especially in high-risk groups such as women with diabetes. We analyze whether sex may modify the effects of diabetes at risk of CAD. Finally, we discuss current diagnostic techniques in th…
Genioplasty with surgical guide using 3D-printing technology: A systematic review.
2019
The purpose of this systematic review is to evaluate the current state of the art of making genioplasties using 3D printing technology.
Hybrid segmentation and exploration of the human lungs
2004
Segmentation of the tracheo-bronchial tree of the lungs is notoriously difficult. This is due to the fact that the small size of some of the anatomical structures is subject to partial volume effects. Furthermore, the limited intensity contrast between the participating materials (air, blood, and tissue) increases the segmentation of difficulties. In this paper, we propose a hybrid segmentation method which is based on a pipeline of three segmentation stages to extract the lower airways down to the seventh generation of the bronchi. User interaction is limited to the specification of a seed point inside the easily detectable trachea at the upper end of the lower airways. Similarly, the comp…
The Tongue, Mandible, Hyoid System.
2017
The craniocervical-mandibular system works in harmony and allows different functional tasks as the postural control of the cervical region. This system is formed by the temporomandibular joint, the masticatory muscles and ligaments connecting the temporomandibular joint and the cervical region. It has been seen to affect human posture, and many disorders of the temporomandibular joints may affect this functional arrangement. Notwithstanding this system considered as a functional arrangement, may offer various clinical explanations, it does not hold anatomical connections with the posterior region of the cranium, thus it should not be refered to as a craniocervical arrangement. For this reas…