Search results for "Anna"
showing 10 items of 1027 documents
Association of extent of cannabis use and psychotic like intoxication experiences in a multi-national sample of first episode psychosis patients and …
2021
AbstractBackgroundFirst episode psychosis (FEP) patients who use cannabis experience more frequent psychotic and euphoric intoxication experiences compared to controls. It is not clear whether this is consequent to patients being more vulnerable to the effects of cannabis use or to their heavier pattern of use. We aimed to determine whether extent of use predicted psychotic-like and euphoric intoxication experiences in patients and controls and whether this differs between groups.MethodsWe analysed data on patients who had ever used cannabis (n = 655) and controls who had ever used cannabis (n = 654) across 15 sites from six countries in the EU-GEI study (2010–2015). We used multiple regres…
Sintētisko kanabinoīdu un katinonu identifikācijas iespējas
2016
Vēl aizvien nelegālajā apritē parādās jaunas psihoaktīvās vielas, kuru identificēšanas iespējas ir apgrūtinātas un maz pētītas. Jaunās psihoaktīvās vielas ir potenciāls sabiedrības veselības drauds. Populārākās ir sintētiskie kanabinoīdi un sintētiskie katinoni. To iedarbība uz cilvēka organismu ir maz pētīta un neparedzama. Lai pētītu to iedarbību uz cilvēka organismu, ir nepieciešamas efektīvas un visaptverošas pētniecības metodes. Darba ir apkopoti dati par Latvijā biežāk sastopamajām jaunajām psihoaktīvajām vielām, kā arī apkopoti un analizēti dati par šo vielu noteikšanas metodēm, kā pielietojamāko metodi nosakot jauno psihoaktīvo vielu noteikšanu, var uzskatīt GH-MS/MS metodi. Atslēgv…
Molecular structure of the cell wall receptor for killer toxin KT28 in Saccharomyces cerevisiae
1988
The adsorption of the yeast killer toxin KT28 to susceptible cells of Saccharomyces cerevisiae was prevented by concanavalin A, which blocks the mannoprotein receptor. Certain mannoprotein mutants of S. cerevisiae that lack definite structures in the mannan of their cell walls were found to be resistant to KT28, whereas the wild-type yeast from which the mutants were derived was susceptible. Isolated mannoprotein from a resistant mutant was unable to adsorb killer toxin. By comparing the resistances of different mannoprotein mutants, information about the molecular structure of the receptor was obtained. At least two mannose residues have to be present in the side chains of the outer chain …
Investigation of a Killer Strain of Zygosaccharomyces Bailii
1993
Summary: The yeast Zygosaccharomyces bailii strain 412 was found to liberate a killer toxin (KT412) lethal to sensitive strains of Saccharomyces cerevisiae and Candida glabrata. Culture supernatants of the killer strain were concentrated by ultrafiltration and the extracellular protein was purified by gel filtration and ion-exchange chromatography. Gel filtration and SDS-PAGE of the electrophoretically homogeneous killer protein indicated an apparent molecular mass of 10 kDa. The killer toxin KT412 is probably not glycosylated since it did not show any detectable carbohydrate structures. KT412 was bound to sensitive but not to resistant yeast cells. The mannan, and not the glucan, fraction …
Determination of Third-Generation Synthetic Cannabinoids in Oral Fluids.
2020
Abstract A procedure has been developed for the determination of third-generation synthetic cannabinoids in oral fluid samples by using a semi-automated microextraction by packed sorbent (MEPS) procedure and gas chromatography–mass spectrometry (GC–MS) determination. Five synthetic cannabinoids were employed as model compounds 5F-ADB, MMB-CHMICA, THJ-2201, CUMYL-4CN-BINACA and MDMB-CHMCZCA. The most adequate operative conditions for MEPS were evaluated giving quantitative recoveries, from 89 to 124%, in synthetic and field saliva samples spiked with 125 and 250 μg/L of the studied cannabinoids, with the exception of MDMB-CHMCZCA in field saliva samples that provided slightly lower recoverie…
Info-communicationnal approach of medical cannabis self-medication : analysis of figures mobilized in knowledge legitimation within a community dedic…
2022
This thesis proposes an infocommunicational approach to self-medication with medical cannabis. We question the logic of knowledge legitimization in a context where the coercive power of the French state is exercised. We seek to understand how the use of cannabis is determined in a radically constrained legislative framework, for users in a recreational or self-medication approach, but also for doctors and patients in a medical approach. To do this, we analyze the processes of knowledge legitimization that allow the development of practical know-how allowing individuals to consume cannabis in a self-medication approach within clandestine health communities of practice, supported by participa…
Hidden connections: Network effects on editorial decisions in four computer science journals
2018
Abstract This paper aims to examine the influence of authors’ reputation on editorial bias in scholarly journals. By looking at eight years of editorial decisions in four computer science journals, including 7179 observations on 2913 submissions, we reconstructed author/referee-submission networks. For each submission, we looked at reviewer scores and estimated the reputation of submission authors by means of their network degree. By training a Bayesian network, we estimated the potential effect of scientist reputation on editorial decisions. Results showed that more reputed authors were less likely to be rejected by editors when they submitted papers receiving negative reviews. Although th…
The characteristics of Menippean satire in Seneca, Lucianus and Erasmus
1999
Tämän pro gradu -tutkielman tarkoitus oli selvittää kreikkalais-roomalaisen menippolaisen satiirin lajityypilliset piirteet neljän esimerkkiteoksen (kahden latinankielisen ja kahden kreikankielisen) sekä muiden asiaan vaikuttavien dokumenttien pohjalta. Tutkimusmateriaalina olivat Senecan (4-65 jKr.) menippolais-satiiri Apocolocyntosis, Erasmus Rotterdamilaisen (1469-1536) Julius exclusus e coelis sekä kreikaksi kirjoittaneen Lukianoksen (120-180) satiirit lkaromenippos ja Nekyomanteia. Seneca kuvaa keisari Claudiuksen kohtaloa hänen saavuttuaan kuolemansa jälkeen taivaan portille, Erasmus paavi Julius II:a, joka joutui taivaassa tekemään Pyhälle Pietarille tiliä toimistaan maan päälla. Luk…
Kuka oli Lucilius? : tutkielma Senecan moraalikirjeiden vastaanottajasta
2007
Roomalaisen valtiomiehen ja filosofin, Lucius Annaeus Senecan (n. 5 eaa.-65 jaa.), ystävälleen Luciliukselle omistama kirjekokoelma Epistulae morales on yksi latinankielisen kirjallisuuden merkittävimpiä teoksia. Seneca vastaavasti on hopealatinan ajan kirjallisuuden merkittävimpiä auktoreita. Kokoelman kirjeet on kirjoitettu Senecan viimeisinä elinvuosina ja niiden asiasisältö on pääasiassa filosofinen. Tutkielmassani selvitän kirjekokoelmasta löytyviä esimerkkejä avaamalla kysymystä siitä, oliko Senecan ja Luciliuksen välinen kirjeenvaihto reaalista vai oliko kirjemuoto vain Senecan käyttämä tyylikeino. Kokoelmasta on löydettävissä kumpaakin argumenttia tukevia näytteitä. Senecan kirjeide…