Search results for "Anna"
showing 10 items of 1027 documents
Identification of glucan-mannoprotein complexes in the cell wall of Candida albicans using a monoclonal antibody that reacts with a (1,6)- -glucan ep…
1995
The use of a novel monoclonal antibody (mAb) that reacts with (1,6)-beta-glucan has permitted the study of the different covalent linkages between glucan and mannoproteins in the cell wall of Candida albicans. The mAb JRR1 was originally raised by immunization with Zymolyase extracts from C. albicans cell walls, but it soon became apparent that it reacted with a (1,6)-beta-glucan epitope. By using this antibody, we show the existence of glucan-mannoprotein complexes between the (1,6)-beta-glucan epitope recognized by the antibody and cell wall mannoproteins. The topology of the (1,6)-beta-glucan in the cell wall of C. albicans has also been studied.
Invasive catfish in northern Italy and their impacts on waterbirds
2022
Predatory fish have occasionally been observed preying on birds, sometimes repeatedly, but few studies were able to unravel the overall significance of avian prey in fish diet and the predation impacts on bird populations. We used a control/impact study setup, using a Nature Reserve in northern Italy and a nearby control area, to determine: 1) the contribution of waterbirds to wels catfish diet in the Reserve, 2) the population density of wels catfish in the Reserve and control area and 3) the potential impacts of waterbird depredation by wels catfish on waterbird population trends. Our stable isotope Bayesian mixing model indicated that birds contributed 12.2% (5–27.9%, 50% confidence inte…
Mechanisms of endothelial cell activation by endocannabinoid 2-arachidonoylglycerol
2020
Abstract Background Endothelial dysfunction promotes atherogenesis, vascular inflammation, and thrombus formation. Reendothelialization after angioplasty is required in order to restore vascular function and to prevent stent thrombosis. The endocannabinoid (eCB) 2-arachidonoylglycerol (2-AG) is a known modulator of inflammation. Earlier studies have demonstrated the relevance of this endocannabinoid in human pathophysiology during coronary artery disease and in murine experimental atherogenesis. However, evidence on the impact of 2-AG on endothelial cell function remains scarce. Methods Endothelial repair was studied in two treatment groups of wildtype mice following electrical denudation o…
Evolution and Immune Function of Fish Lectins
2016
Abstract Lectins are sugar-binding proteins widely distributed among animals, plants, and microbial taxon, involved in diverse biological processes. In both invertebrates and vertebrates, they play key roles in nonself recognition and immune responses, such as nonself recognition, inflammatory processes, and immunomodulation. In fish, many lectin families have been identified, and their tissue-specific expression and localization of the various lectin repertoires and their ligands are consistent with their distinct biological roles in innate and adaptive immunity. Here, we discuss the involvement of F-type lectins, rhamnose-binding lectins, galectins, and C-type lectins in pathogen recognit…
Characterization of aSchizosaccharomyces pombemorphological mutant altered in the galactomannan content
1991
In a search for Schizosaccharomyces pombe mutants resistant to the antifungal agent papulacandin B, a morphological mutant was isolated. The mutant is round shaped in contrast to the rod shaped parental strain. This morphological defect segregated as a recessive Mendelian character and was not observed in other papulacandin B resistant mutants belonging to the same complementation group. The mutation mapped in the right arm of S. pombe chromosome III very close to pap1 marker. Mutant cell walls were more susceptible to alkali extraction and Novozyme degradation than those from the wild-type. A specific reduction in the cell wall galactomannan fraction was the only significant difference det…
(Z)-dodec-3-en-1-ol, a novel termite trail pheromone identified after solid phase microextraction from Macrotermes annandalei
2001
0022-1910 (Print) Journal Article; (Z)-dodec-3-en-1-ol was isolated and identified by GC-MS as the major component of the trail-following pheromone from whole body and sternal gland extracts of workers of the fungus-growing termite, Macrotermes annandalei (Silvestri) (Termitidae, Macrotermitinae). For the first time, this trail pheromone was also identified by using solid phase microextraction from the surface of the secretory sternal gland of workers. Bioassays showed that synthetic dodecenol induced both orientation and recruitment behavioral effects. The activity threshold of (Z)-dodec-3-en-1-ol in eliciting trail-following is similar to that of (3Z,6Z,8E)-dodeca-3,6,8-trien-1-ol in the …
2021
In this review, state-of-the-art evidence on the relationship between cannabis use, traffic crash risks, and driving safety were analyzed. Systematic reviews, meta-analyses, and other relevant papers published within the last decade were systematically searched and synthesized. Findings show that meta-analyses and culpability studies consistently indicate a slightly but significantly increased risk of crashes after acute cannabis use. These risks vary across included study type, crash severity, and method of substance application and measurement. Some studies show a significant correlation between high THC blood concentrations and car crash risk. Most studies do not support this relationshi…
Modulators of Endogenous Neuroprotection: Estrogen, Corticotropin-releasing Hormone and Endocannabinoids
2005
Age-associated neurodegenerative disorders are among the most challenging problems of our aging society. Alzheimer’s disease is affecting people with increasing frequency, since there is a clear relationship between the incidence of this detrimental disorder and age. Other neurodegenerative disorders, including Parkinson’s disease, stroke and amyotrophic lateral sclerosis, are also frequently observed in our aging society. For most of these diseases, no causal therapy has yet been identified. Many of the treatments given to patients that are affected by these disorders have different side effects, and therefore the search is on to identify novel molecular approaches that may lead to a more …