Search results for "Antoni"
showing 10 items of 359 documents
The Synthesis of Bioactive Sesquiterpenes from Santonin
2000
Abstract This article reviews the literature published in the last decade dealing with the transformation of α-santonin into bioactive or potentially bioactive sesquiterpenes. A number of syntheses starting from 8α-hydroxysantonin (artemisin) have also been included. Special emphasis has been placed on synthesized products that show biological activity. Major advances in this field include the application of new reagents and methodologies for the structural modification of the santonin skeleton and functionality, and its transformation into other sesquiterpenes, especially sesquiterpene lactones. The review has been organised into five parts: 1. Introduction: An overview of the structure an…
Stereoselective Synthesis of 8,12-Furanoeudesmanes from Santonin. Absolute Stereochemistry of Natural Furanoeudesma-1,3-diene and Tubipofurane.
1996
Ketobutenolide 3, easily obtained from santonin (1), has been transformed into two natural furanoeudesmanes 4 and 5, isolated from Commiphora molmol and Tubipora musica, respectively. trans- And cis-decalin systems were obtained by stereoselective reduction of the C(4)-C(5) double bond in 3 in the following way: hydrogenation of 3 over Pd/C followed by acidic treatment gave the cis isomer 10 as the major product; selective hydrogenation of the C(1)-C(2) double bond with the Wilkinson's catalyst followed by reduction with NaTeH yielded mainly the trans isomer 9. Compounds 9 and 10 were transformed into 4 and 5 in parallel sequences. Optical rotation and CD measurements of the synthetic produ…
ChemInform Abstract: Synthesis of Plagiochiline N from Santonin.
2010
This article reports the transformation of O-acetylisophotosantonin, obtained by photochemical rearrangement of santonin, into plagiochiline N, an ent-2,3-secoaromadendrane isolated from Plagiochila ovalifolia. The synthesis was carried out in a sequence involving as the key steps (a) the substitution of the lactone moiety by a gem-dimethylcyclopropane ring through a synthetic intermediate having a C(6)-C(7) double bond and (b) the ozonolysis of the C(2)-C(3) bond followed by cyclization to the dihydropyran ring characteristic of plagiochiline N. Spectroscopic data of the synthetic product fully coincided with the reported data for the natural product.
Synthetic studies toward natural furanosesquiterpenoids from santonin. Synthesis of (+)-1,2-dihydrotubipofuran
1994
Abstract Santonin (1) was converted into (+)-1,2-dihydrotubipofuran (13) via a synthetic pathway involving a very easy preparation of 7,11-ene-8,12-olide and 8,12-furan moieties and A-ring elaboration on the eudesmane framework.
Synthesis of Elemane Bis-Lactones from Santonin – Synthesis of the Reported Structure ofseco-Isoerivanin Pseudo Acid and Formal Synthesis of (+)-8-De…
2000
The synthesis of the reported structure for seco-isoerivanin pseudo acid (1) and of an elemane bis-lactone 5 from santonin (4) through a common vinylic precursor 12 is described. Compound 5 is a known intermediate in a previous synthesis of the antitumor compound (+)-8-deoxyvernolepin (3). The vinyl group of 12 underwent a regio- and diastereoselective anti addition of an external electrophile and an intramolecular condensation to yield either the selenolactone 13 or the hydroxylactone 17. The lactones 13 and 17 served as key intermediates in the total synthesis of 1 and 5 respectively. A revision of the structure of seco-isoerivanin pseudo acid to the C-10 epimer is suggested on the basis …
Il senso comune nei Quaderni del carcere di Gramsci
2021
Si tratta di uno studio sul concetto di senso comune in Antonio Gramsci The essay reconstructs the concept of "common sense" in Antonio Gramsci
Regionalisme i drets humans
2012
Conferència sobre regionalisme i drets humans donada en el congrés de lleis regionals e internacionals realitzat en València del 13 al 15 de Septembre.
Regionalisme i globalització
2012
Xerrada sobre regionalisme i globalització donada al congrés sobre lleis regionals i internacionals realitzat a València del 13 al 15 de setembre.
Logística, trabajo y almacenes: el lado oscuro de la digitalización
2021
Le bucher de Saint Antoine. Rites du feu en Sicile
2008
In Sicilia roghi, falò e fiaccolate si incontrano in numerose celebrazioni che si susseguono lungo il corso dell’anno (Buttitta I. E. 1999a). Questi sono diffusamente accesi la vigilia delle feste dell’Immacolata (8 dicembre), di Santa Lucia (13 dicembre), di Natale (25 dicembre), di Sant’Antonio Abate (17 gennaio), di San Giuseppe (19 marzo). Fuochi rituali ricorrono anche in occasione del Martedì grasso di Carnevale, della Pasqua (Venerdì santo e Sabato santo), dell’Ascensione, della vigilia dell’Assunzione (15 agosto), di San Giovanni Battista (24 giugno) e di alcune feste di carattere locale. I vampi, i vamparotti, i pagghiara, i burgi, i fochi, a ddera (queste solo alcune delle denomin…