Search results for "Anus"

showing 10 items of 841 documents

Significance of immunohistochemistry biomarkers in prediction of malignant transformation of oral lichen planus

2022

Background: Oral lichen planus (OLP) is a chronic inflammatory disorder with increased risk for malignant transformation. Biomarker validation is a pivotal step in moving newly discovered biomarkers towards clinical implementation. We performed a systematic review of studies on biomarkers related to OLP, wherein biomarkers have been described in at least two independent studies. Our aim was to determine whether any of these biomark-ers might be promising in predicting the increased risk of malignant transformation of OLP. Material and Methods: We searched the following databases until August 2021: PUBMED, EMBASE, and Web of Science. Due to high heterogeneity, a qualitative rather than quant…

bisphosphonate osteonecrosisp53malignant transformationP21bone densitybiomarkerscomputed tomographycervical vertebraeImmunohistochemistryCell Transformation NeoplasticjawOtorhinolaryngologySDG 3 - Good Health and Well-beingProliferating Cell Nuclear AntigenOral lichen planusBCl-2Humans/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingPCNAMouth NeoplasmsSurgeryGeneral DentistryUNESCO:CIENCIAS MÉDICASLichen Planus OralMedicina oral patologia oral y cirugia bucal
researchProduct

Janus Nanostructures from ABC/B Triblock Terpolymer Blends

2019

Lamella-forming ABC triblock terpolymers are convenient building blocks for the synthesis of soft Janus nanoparticles (JNPs) by crosslinking the B domain that is &ldquo

bulk morphologiestechnology industry and agricultureChemiemacromolecular substancesArticlelcsh:QD241-441block copolymersForschungszentren » Center for Nanointegration Duisburg-Essen (CENIDE)lcsh:Organic chemistryddc:540DPD simulationspolymer blendingddc:541Janus nanostructuresFakultät für Chemie » Physikalische ChemiePolymers
researchProduct

A Controlled Trial of Two Acellular Vaccines and One Whole-Cell Vaccine against Pertussis

1996

Background Concern about both safety and efficacy has made the use of whole-cell pertussis vaccines controversial. In some European countries, including Italy, the rate of vaccination against pertussis is low. Methods We conducted a double-blind trial in Italy in which infants were randomly assigned to vaccination at two, four, and six months of age with an acellular pertussis vaccine together with diphtheria and tetanus toxoids (DTP); a DTP vaccine containing whole-cell pertussis (manufactured by Connaught Laboratories); or diphtheria and tetanus toxoids without pertussis (DT). The acellular DTP vaccine was either one containing filamentous hemagglutinin, pertactin, and pertussis toxin ina…

business.industryDiphtheriaFilamentous haemagglutinin adhesinGeneral Medicinemedicine.diseasePertussis toxincomplex mixturesVirologyVaccinationImmunologymedicineDiphtheria-Tetanus VaccinePertactinbusinessDiphtheria-Tetanus-acellular Pertussis VaccinesWhooping coughNew England Journal of Medicine
researchProduct

Oral lichenoid lesions related to contact with dental materials: A literature review

2007

Oral lichenoid lesions related to contact are defined as oral-cavity eruptions with an identifiable etiology, and are clinically and histologically similar to oral lichen planus. Within this group are found oral lichenoid lesions related to contact with dental materials (OLLC), the most common being those related to silver amalgam. Currently, it remains difficult to diagnose these lesions due to the clinical and histopathological similarity with oral lichen planus and other oral mucosa lesions of lichenoid characteristics. In the present paper, we carry out an updated review of the tests for, and the different characteristics of OLLC, which may aid the diagnosis. For this review, we made se…

business.industryMEDLINEDentistry:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseDental Materialsstomatognathic diseasesmedicine.anatomical_structureOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASEtiologyHumansMedicineSurgeryOral lichen planusOral mucosabusinessGeneral DentistryLichenoid lesionsPathologicalLichen Planus OralCohort studyMedicina Oral Patología Oral y Cirugia Bucal
researchProduct

Wild-type JAK2 secondary acute erythroleukemia developing after JAK2-V617F-mutated primary myelofibrosis.

2009

A 54-year-old female patient developed acute erythroleukemia after an 8-year course of primary myelofibrosis. The latter harbors the JAK2-V617F mutation and was treated with hydroxyurea and anagrelide. A bone marrow trephine biopsy disclosed 2 morphologically distinct areas of chronic primary myelofibrosis and acute erythroleukemia. Microdissection and a separate molecular pathological analysis was performed. Although the activating JAK2-V617F mutation was not maintained in blasts of acute erythroleukemia, it was detectable in the chronic phase of primary myelofibrosis, indicating that this mutation did not play a role in the leukemic transformation of erythroid cells.

business.industryWild typeHematologyGeneral MedicineAnagrelideJanus Kinase 2Middle Agedmedicine.diseaseCell Transformation NeoplasticFatal OutcomePrimary Myelofibrosishemic and lymphatic diseasesMutation (genetic algorithm)Female patientCancer researchMedicineAcute erythroleukemiaHumansFemaleLeukemia Erythroblastic AcutebusinessMyelofibrosisJAK2 V617Fmedicine.drugActa haematologica
researchProduct

A Poem for All Seasons: Alcuin’s “O vos, est aetas”

2017

There is no complete account of the transmission of Alcuin’s poems, which is apparently quite unpredictable if not random. The circulation of a number of short compositions, which accompany his treatises and his letters, and their circulation together, is so far uncharted. Particularly intriguing is the manuscript tradition of “O vos, est aetas,” a poem in seven distichs, in which young men are encouraged to learn rhetoric and to cultivate virtue. The poem generally occurs in connection with two prose works by Alcuin, the De dialectica (henceforth DD) and the Disputatio de rhetorica et virtutibus (henceforth DR). It may be copied either between the two treatises, before the prologue poem of…

carminaanglo-saxon englandSettore L-FIL-LET/15 - Filologia Germanicao voAlcuinmanuscripts
researchProduct

La biblioteca del canónigo Matíes Mercader (+1489)

1987

Estudio sobre la biblioteca del canónigo Matíes Mercader (+1489)

catedral de ValenciaincunablesmanuscritosUNESCO::HISTORIA:HISTORIA [UNESCO]bibliotecas medievales
researchProduct

Manuskrypt cechu krawców ze zbiorów Archiwum Państwowego w Opolu. Edycja krytyczna

2016

Anonimowy dokument z Archiwum Państwowego w Opolu włączony do zbioru „Cechy miasta Opola z lat 1470-1934, 123” o sygnaturze 80 jest zabytkiem, który ukazuje dzieje kultury materialnej z zakresu rzemiosła krawców i kostiumologii. Datowany jest on na około 1700 rok i z pewnością powstał na Śląsku. Podstawowym składnikiem opolskiego manuskryptu są wykroje w skali 23 prac krawieckich, głównie ubiorów noszonych przy końcu XVII wieku, ale wśród krawieckich szablonów znalazły się także wzory użytkowe, takie jak chorągiew kościelna, namiot wojskowy, strój na konia, dekoracja elewacji domu. Do unikatu wśród tego zbioru należy zaliczyć wykrój kontusza należącego do kompletu ubiorów polskich. Jego obe…

cechmanuscriptOpolekrawiectworękopistailoringguildXVII-XVIII centuryXVII-XVIII wiek
researchProduct

Structure and Shear Response of Janus Colloid–Polymer Mixtures in Solution

2020

We investigate the structure and rheological properties of dilute colloid-polymer mixtures at rest and under shear via molecular simulations that take into account hydrodynamic interactions. Mixtures of amphiphilic Janus colloids (JCs) and hydrophobic/amphiphilic polymers are considered for various solvent qualities and polymer concentrations. Free polymers, small polymer droplets, and hybrid aggregates coexist in mixtures with slightly hydrophobic homopolymers. As the solvent quality worsens, all polymers aggregate into small droplets, covered and stabilized by the JCs. In mixtures with amphiphilic polymers, we observe the coexistence of free polymers, purely polymeric micelles, and hybrid…

chemistry.chemical_classificationAggregation numberMaterials scienceSurfaces and InterfacesPolymerCondensed Matter PhysicsBreakupSolventColloidRheologychemistryChemical engineeringAmphiphileElectrochemistryGeneral Materials ScienceJanusSpectroscopyLangmuir
researchProduct

Enzyme pretreatment and negative pressure cavitation extraction of genistein and apigenin from the roots of pigeon pea [Cajanus cajan (L.) Millsp.] a…

2012

Abstract An enzyme pretreatment and negative-pressure cavitation extraction (E-NPCE) method was investigated for extraction genistein and apigenin from pigeon pea roots. The important parameters involved in E-NPCE process were optimized by single-factor experiments and then critical parameters were investigated by a 2 3 full factorial central composite design (CCD) to optimize extract conditions. Under optimal conditions, the yields of genistein and apigenin were 0.628 mg/g and 0.359 mg/g, which represented an increase of 44.70% and 53.05%, respectively, compared to standard NPCE. Furthermore, from DPPH scavenging activity test the extract of E-NPCE showed better antioxidant activity than t…

chemistry.chemical_classificationAntioxidantChromatographyCentral composite designbiologymedicine.medical_treatmentExtraction (chemistry)GenisteinDpph scavengingbiology.organism_classificationchemistry.chemical_compoundCajanusEnzymechemistryApigeninmedicineAgronomy and Crop ScienceIndustrial Crops and Products
researchProduct