Search results for "Apparatu"
showing 10 items of 195 documents
Membrane Integration of Poliovirus 2B Viroporin
2011
Virus infections can result in a variety of cellular injuries, and these often involve the permeabilization of host membranes by viral proteins of the viroporin family. Prototypical viroporin 2B is responsible for the alterations in host cell membrane permeability that take place in enterovirus-infected cells. 2B protein can be localized at the endoplasmic reticulum (ER) and the Golgi complex, inducing membrane remodeling and the blockade of glycoprotein trafficking. These findings suggest that 2B has the potential to integrate into the ER membrane, but specific information regarding its biogenesis and mechanism of membrane insertion is lacking. Here, we report experimental results of in vi…
Theory and Simulations of Friction between Flat Surfaces Lubricated by Submonolayers
2001
Recent simulations suggest that wearless friction between two solid surfaces can only be obtained if the two surfaces are commensurate or if they are lubricated by a film. Some simple theoretical arguments are given why the presence of a submonolayer film between two solids leads to friction. Possible implications of the symmetry of the confining walls on the tribological properties of the system are then investigated in the presence of a thin film by means of molecular dynamics simulation. Erratic stick-slip motion of the incommensurate system and oscillating friction forces for the commensurate system in the sliding regime are observed.
State surveillance as a threat to personal security of individuals
2015
Changes in modern society are crucial to individuals. Article starts with analysis of control in nowadays societies. Then author tries to understand useful categories,as „Panopticon”, „ban-opticon” and „synopticon”. Last part is focused on stete surveillance, i.e. surveillance by American National Security Agency.
State surveillance as a threat to personal security of individuals
2015
Changes in modern society are crucial to individuals. Article starts with analysis of control in nowadays societies. Then author tries to understand useful categories, as "Panopticon", "ban-opticon" and "synopticon". Last part is focused on stete surveillance, i.e. surveillance by American National Security Agency.
Monoclonal antibodies SMI 311 and SMI 312 as tools to investigate the maturation of nerve cells and axonal patterns in human fetal brain
1998
Neurofilaments, which are exclusively found in nerve cells, are one of the earliest recognizable features of the maturing nervous system. The differential distribution of neurofilament proteins in varying degrees of phosphorylation within a neuron provides the possibility of selectively demonstrating either somata and dendrites or axons. Non-phosphorylated neurofilaments typical of somata and dendrites can be visualized with the aid of monoclonal antibody SMI 311, whereas antibody SMI 312 is directed against highly phosphorylated axonal epitopes of neurofilaments. The maturation of neuronal types, the development of area-specific axonal networks, and the gradients of maturation can thus be …
Beobachtungen nach einer neuen optischen Methode: ein Beitrag zur Experimental-Physik
1864
Inhalt: Princip der Beobachtungs-Methode... 2 Specielle Beschreibung des Apparates... 8 Bemerkungen über den Gebrauch und die Adjustirung... 13 Schlieren in Gläsern ... 16 Beobachtungen mittels des Schlieren-Apparates... 18 Veränderung durchsichtiger Körper durch Temperatur und Druck... 19 Diffusionsbewegungen... 21 Untersuchung der Flammen... 23 Beugungsphänomene... 26 Sichtbarmachung der Schallwellen... 27 Beobachtungen über den electrischen Funken... 29 Der Inductionsfunken... 35 Der Flaschenfunken... 42 Schlussbemerkungen... 49
Characterization of the immune cells response and ultrastructural study of dendritic cell Golgi Apparatus role in ORF virus infection
2014
Contagious Ecthyma is an acute skin anthropozoonosis caused by orf virus (ORFV), which affects sheep and goat. The infectious agent is an epitheliotropic, double- stranded DNA poxvirus. Infection happens via the hurt skin, and causes a localized virus production in the epidermal cells and keratinocytes. This paper characterize the cellular immune response by cytochemistry in ORFV infection and studies the role of Golgi Apparatus (GA) of keratinocytes by transmission electron microscopy (TEM) and 3D models. Twenty cutaneous biopsies in sheep from ORFV infected lesions were fixed in 10% formalin and embedded in paraffin for light microscopy. Paraffin sections were immunocytochemically stained…
Failure of ProTaper rotary Ni-Ti instruments used by undergraduate students
2012
Objective: To evaluate the effect of number of uses, angle and radius of curvature and type of instrument on the fracture of ProTaper rotary instruments when used by undergraduate students. Study Design: Three hundred and seventy-six molars, with a total of 1114 root canals, extracted were instrumented by undergraduate students using ProTaper instruments according to the manufacturer´s recommendations. When fracture occurred, data were collected concerning the number of uses, type of instrument, level of fracture, angle and radius of curvature. ANOVA test were used to determine the influence of type of instrument in the incidence of instrument fracture. Logistic regression model was used to…
An unusual conchorhynch from the upper Maastrichtian of the southeast Netherlands and the distinction between nautiloid and ammonoid conchorhynchs (M…
2022
Abstract A single, atypical conchorhynch (calcitic tip of a cephalopod lower jaw), recovered from the uppermost Meerssen Member (Maastricht Formation, upper Maastrichtian) at the former ENCI-HeidelbergCement Group quarry, south of Maastricht, is described as a new parataxon, Conchorhynchus illustris sp. nov. The specimen can be differentiated from all previous conchorhynch records on account of its large size, elongated shape and, in particular, of the structure of its apical part which is smooth and forwardly elongated. During the Late Cretaceous, conchorhynchs formed part of the jaw apparatus of nautilids and of two ammonoid suborders, Phylloceratina and Lytoceratina. Since conchorhynchs …
Synaptopodin regulates denervation-induced homeostatic synaptic plasticity
2013
Synaptopodin (SP) is a marker and essential component of the spine apparatus (SA), an enigmatic cellular organelle composed of stacked smooth endoplasmic reticulum that has been linked to synaptic plasticity. However, SP/SA-mediated synaptic plasticity remains incompletely understood. To study the role of SP/SA in homeostatic synaptic plasticity we here used denervation-induced synaptic scaling of mouse dentate granule cells as a model system. This form of plasticity is of considerable interest in the context of neurological diseases that are associated with the loss of neurons and subsequent denervation of connected brain regions. In entorhino-hippocampal slice cultures prepared from SP-de…