Search results for "Approach"
showing 10 items of 1654 documents
Modélisation de la répartition des assimilats au sein du système racinaire chez le pois de printemps (Pisum sativum)
2014
leguminous plant, can fix atmospheric nitrogen through symbiosis with symbiotic bacteria of the genus Rhizobium. Yet the sensitivity of symbiotic N fixation to biotics and abiotics stresses leads to a significant yield and protein rate variability compared with cereals. A better understanding of C and N partitioning between roots and shoots according to the mode of N nutrition seems necessary to identify levers of yield stabilisation. In this context, the model PeaNod developed within INRA Dijon Ecophysiology team combines an architectural model of pea with an source-sink approach. The main objective of this work was to study the impact of competition between nodules and roots on roots arch…
Impacts of climate change on the performance of an insect pest and associated consequences for tritrophic interactions
2019
Global warming poses a major challenge to living organisms, particularly for ectothermic animals like insects, whose physiology and behaviour are closely related with direct thermal surroundings. This thesis aims at experimentally investigating the impacts of climate change on the overall performance of a major grapevine pest, the European grapevine moth (Lobesia botrana), and the associated consequences for interactions involving this phytophagous insect and adjacent trophic levels, more specifically natural enemies (parasitoids). The experiments conducted focus on three facets of climate change: an increase in mean temperature, an alteration of daily thermal range, and the occurrence of h…
Cannabinoid ligands sorting out by a 3D-QSAR approach using catalyst/hypogen
2009
National audience; Understanding how molecular structures are involved in recognition by a biological receptor is a decisive step in drug design, and could constitute an intricate problem because of existence of several binding sites, as is the case of GPCRs (1) that constitute the largest class of membrane receptors. In this context, identification of pharmacophores that should differentiate multiple binding modes is of particular interest. We have recently applied to ligands of a human olfactory receptor an original sorting-out procedure carried out using Catalyst/HypoGen software (Accelrys Ltd) (2). We aimed to validate this sorting out procedure using literature data, and in this way, w…
Arbuscular mycorhizal proteomes: what news at the nearby and distant horizon?
2007
International audience; Proteomics has soon emerged as a powerful tool to point out protein modifications in roots interacting with arbuscular mycorrhiza (AM) fungi. Depending on the developmental mycorrhizal stage and on the available amount of mycorrhizal material, untargeted and/or sub-cellular proteomic approaches were applied to reveal and identify proteins whose accumulation was modified during the AM colonisation of Medicago truncatula roots. For the early stage of symbiosis, the protein patterns obtained from noninoculated roots and roots synchronized for appressorium formation in wild-type (Jemalong J5), penetration-defective (TRV25, dmi3) and autoregulation-defective (TR122, sunn)…
New insights into the use of rhizobia to mitigate soil N2O emissions
2022
Agriculture is a major anthropogenic source of the greenhouse gas N2O, which is also involved in stratospheric ozone depletion. While the use of rhizobial inoculants has already been reported as an emerging option for mitigating soil N2O emissions, this study presents an in situ abatement of 70% of soil N2O emission using the strain nosZ+ G49 vs. nosZ− USDA138 in association with soybean. Therefore, we consider that the choice of the inoculant strain of a leguminous crop should take into account the capacity of strains to reduce nitrous oxide in addition to their N fixation capacity. This study also clearly suggests that this mitigation option could be considered not only for soybean but al…
Modelling Keloids Dynamics: A Brief Review and New Mathematical Perspectives
2022
The keloids are fibroproliferative disorders described by an excessive growth of fibrotic tissue, which also invades adjacent areas (beyond the original wound borders). Since these disorders are specific to humans (no other animal species naturally develop keloid-like tissue), the experimental in vivo/in vitro research has not lead to significant advances in this field. One possible approach could be to combine in vitro human models with calibrated in silico mathematical approaches (i.e., models and simulations) to generate new testable biological hypotheses related to biological mechanisms and improved treatments. Since these combined approaches do not really exist for keloid disorders, in…
Transcriptomic and proteomic responses of Microbacterium sp. C448 exposed to sulfamethazine antibiotic
2022
International audience; The Microbacterium sp. C448 was isolated from a soil regularly exposed to sulfamethazine(SMZ), for its ability to partly mineralise this antibiotic and other related sulfonamides.The aim of our study was to explore its metabolic adaptation towards exposure to SMZenvironmental (10 mg/L) and medicinal (250 mg/L) concentrations. Its transcriptomic andproteomic responses were analysed by focusing on the degradation regulon (sad genes) andresistance genes (folP and sul1).The transcriptomic and proteomic results were essentially congruent whatever theconcentrations tested. In culture conditions, exposure to the highest concentration of SMZ led tothe highest sad expression …
Protection de la ressource en eau du bassin de l’Auxerrois et transformation des pratiques agricoles
2022
Avec des taux de nitrates dépassant les seuils définis par la Directive européenne « nitrates », puis la présence de résidus de pesticides utilisés par les activités agricoles du secteur, l’eau des bassins d’alimentation de captages de l’Auxerrois fait l’objet de préoccupations depuis une trentaine d’année. C’est ainsi qu’à la fin des années 1990, les représentants des pouvoirs publics ont choisi de mettre en place une démarche préventive passant par un travail de transformation des pratiques agricoles. Notre article analyse comment la prise en charge collective de cette situation participe à la configuration des relations entre représentants des pouvoirs publics, agriculteurs et défenseurs…
Handcrafting in archaeomusicological research
2016
There were no conference proceedings but you may find video recordings of some of the talks by following the link above; International audience; Archaeological flutes, as sound artefacts, both stand in material and immaterial culture. They are made of tremendous subtleties that archaeologists have a hard time to understand while these are craftsmen's everyday life. These subtleties are the link between material (rough material, tools, gestures) and immaterial (sounds, music, timber, uses) issues. They are the reason why archaeology cannot study ancient sound instruments on its own. A one-year insight experience of apprenticeship alongside a traditional-flute-maker (Jean-Daniel Talma, ElBock…
Ressources naturelles et développement dans le monde tropical : les contradictions entre dynamiques écologiques, reproduction sociale et ordre économ…
2013
Natural resources are in the midst of contradictory dynamics. While they are essential to the reproduction of societies and life, actual organization of the world economy subordinates them to logics of accumulation. In addition to the fact that these logics don't take into account (consider) the physical limits inside of which humanity evolves, they induce problematic socio-ecological inequalities at different scales. Indeed, actual international economic order tends to generate ecologically unequal exchanges, which disrupt the development of primary exporting countries and threaten the most vulnerable populations and ecosystems inside of them.Tropics are the typical context in which such c…