Search results for "Approache"
showing 10 items of 141 documents
Disconnected Graph Layout and the Polyomino Packing Approach
2002
Conference name: GD: International Symposium on Graph Drawing 9th International Symposium Date of Conference: 23–26 September 2001 We review existing algorithms and present a new approach for layout of disconnected graphs. The new approach is based on polyomino representation of components as opposed to rectangles. The parameters of our algorithm and their influence on the drawings produced as well as a variation of the algorithm for multiple pages are discussed. We also analyze our algorithm both theoretically and experimentally and compare it with the existing ones. The new approach produces much more compact and uniform drawings than previous methods. © Springer-Verlag Berlin Heidelberg …
Re-Clustering tool using an Open-Reference method that improves OTU definition
2019
International audience; 1.Environmental microbial communities are now widely studied using metabarcoding approaches, thanks to the democratization of high‐throughput DNA sequencing technologies. The massive number of reads produced with these technologies requires bioinformatic solutions to be treated. A key step in the analysis is to cluster reads into Operational Taxonomic Units (or OTUs) and thus reduce the amount of data for downstream analyses. Due to the important impact of the clustering method on the quantity and quality of OTUs, finding an equilibrium between the reliability and time‐consuming nature of the chosen strategy is a real challenge. The present article proposes a new pos…
Pharmacogenetics of treatments for pancreatic cancer
2019
Introduction: Despite clinical efforts, pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis. The scarcity of effective therapies can be reflected by the lack of reliable biomarkers to adapt anticancer drugs prescription to tumors’ and patients’ features. Areas covered: Pharmacogenetics should provide the way to select patients who may benefit from a specific therapy that best matches individual and tumor genetic profile, but it has not yet led to gains in outcome. This review describes PDAC pharmacogenetics findings, critically reappraising studies on polymorphisms and -omics profiles correlated to response to gemcitabine, FOLFIRINOX, and nab-paclitaxel combinations, as well as l…
Fetal Calf Serum-Free Generation of Functionally Active Murine Dendritic Cells Suitable for In Vivo Therapeutic Approaches
2000
Standard protocols to generate mouse dendritic cells (DC) generally use culture medium supplemented with fetal calf serum; however, reinjection in vivo of DC cultured in fetal calf serum results in priming to xenogeneic proteins that clearly limits the use of such DC. We therefore established a fetal calf serum-free culture system for the generation of murine DC from bone marrow precursors. DC can be generated fetal calf serum-free using RPMI supplemented with 1.5% syngeneic mouse serum. Although the yield of DC grown under fetal calf serum-free conditions was somewhat lower than that of the standard culture, large numbers of DC could be generated without the exposure to xenogeneic proteins…
Pedagogical Practices for Virtual Worlds
2010
As a result from activities carried out within Module 2 of the MUVEnation programme about exploring active learning approaches, we have created a collection of practices for teaching and learning in Virtual Worlds, organised in 21 chapters, classified in the following categories of instructional methods: Presentation, Demonstration, Discussion, Drill-and-practice, Tutorial, Cooperative Learning, Gaming, Simulation and Discovery. The educational professionals who participated in the course worked in teams, but in some cases individually to map and describe the existing range of teaching practices in Second Life, and to draw a reflection about the elements for their success. Practices describ…
Oral cancer and treatment information involved in therapeutic decision-making
2019
Early detection of oral cancer improves survival after treatment and the quality of life. The adoption of standardized methodological protocols of screening has increased the possibilities for early identification and appropriate treatment. The informed consent must be obtained by patients before any treatment and/or surgical procedure. The clinical and surgical details must be discussed with the patient, as well as potential risks and benefits. Consent must be documented in the medical record and consent forms may serve to document the physician's discussion with the patient. Objectives. all dentists are trained to detect the early signs of oral cancer. The health professional have a key r…
Urticaria in Pediatrics and During Pregnancy and Lactation: Highlights on Epidemiology, Diagnosis, and Management
2021
Chronic urticaria (CU) in children as in adults is characterized by the presence of itchy wheals, angioedema, or both daily or almost daily for at least 6 weeks. Most cases of urticaria in the pediatric age group are acute [1–4]. CU is sub-classified as spontaneous (occurring without a known trigger) or inducible. There are also cases of spontaneous and inducible forms that co-exist. The chronic subtypes occur continuously but also recurrently, often in association with infections. In this chapter we will touch briefly on the clinical presentation, diagnosis, and management of acute urticaria in children. However, our primary goal is to highlight key findings regarding the epidemiology, dia…
Enfoques y concepciones docentes en la universidad
2014
La investigación pretende conocer los enfoques y concepciones sobre docencia del profesorado universitario a lo largo de su trayectoria profesional. Desde la fenomenografía pero con enfoque metodológico mixto, nuestro análisis muestra gran variabilidad respecto cómo los docentes comprenden y expresan sus experiencias y concepciones sobre docencia. Éstas se pueden clasificar en: impartir conocimiento, entusiasmar y motivar, desarrollar habilidades y cambiar concepciones en los estudiantes; con combinaciones entre ellas. Las categorías se ordenan de mayor a menor comprensión de la docencia, son progresivas e inclusivas. Los enfoques docentes no tienen relación con la edad, experiencia, discip…
Short form of revised two-factor study process questionnaire: Development, validation, and cross-validation in two European countries
2022
Determining your own grade – Student perceptions on self-assessment in a large mathematics course
2018
International audience; In our poster, we report on students' perceptions on self-assessment in large undergraduate course context taught with the DISA model (Digital Self-Assessment) in which the final exam is replaced by self-assessment. The students found that practising self-assessment skills was valuable and encouraged them to study for themselves. At the same time, self-assessment was considered unfamiliar and therefore difficult. We argue that the DISA model encouraged students to take more responsibility on their own learning.