Search results for "Array"

showing 10 items of 1264 documents

A wavelet-based demosaicking algorithm for embedded applications

2010

This paper presents an alternative to the spatial reconstruction of the sampled color filter array acquired through a digital image sensor. A demosaicking operation has to be applied to the raw image to recover the full-resolution color image. We present a low-complexity demosaicking algorithm processing in the wavelet domain. Produced images are available at the output of the algorithm either in the spatial representation or directly in the wavelet domain for high-level post processing in the latter domain. Results show that the computational complexity has been lowered by a factor of five compared to state of the art demosaicking algorithms.

DemosaicingComputer scienceColor imagebusiness.industryComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISIONWavelet transformIterative reconstructionDigital imageWaveletColor filter arrayComputer visionArtificial intelligencebusinessImage resolutionAlgorithm2010 Conference on Design and Architectures for Signal and Image Processing (DASIP)
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Adaptogens in chemobrain (Part I): Plant extracts attenuate cancer chemotherapy-induced cognitive impairment – Transcriptome-wide microarray profiles…

2019

Abstract Background Cancer chemotherapy-induced cognitive impairments are presumably associated with undesirable effects of chemotherapy on physiological functions of brain cells. Adaptogens are natural compounds or plant extracts increasing an organism's adaptability and survival in stress. They exhibited neuroprotective effects and increased cognitive functions in clinical studies in human beings. Hypothesis We hypothesized that selected adaptogenic plant extracts attenuate or prevent cancer chemotherapy-induced cognitive impairments. Aim We assessed the effects of selected adaptogenic herbal extracts on FEC (fixed combination 5-fluorouracil, epirubicin and cyclophosphamide) induced chang…

MicroarrayPharmaceutical ScienceBiologyPharmacologyNeuroprotectionCell LineTranscriptome03 medical and health sciences0302 clinical medicineAntineoplastic Combined Chemotherapy ProtocolsDrug DiscoverymedicineHumansCognitive DysfunctionCyclophosphamideEpirubicinOligonucleotide Array Sequence AnalysisSchisandra030304 developmental biologyPharmacology0303 health sciencesPlant ExtractsMicroarray analysis techniquesGene Expression ProfilingAxon extensionNeurogenesisGene expression profilingmedicine.anatomical_structureGene Expression RegulationComplementary and alternative medicineFruit030220 oncology & carcinogenesisMolecular MedicineNeurogliaAndrographisNeurotoxicity SyndromesRhodiolaFluorouracilDiterpenesNeurogliaPhytomedicine
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Downregulation of a Chitin Deacetylase-Like Protein in Response to Baculovirus Infection and Its Application for Improving Baculovirus Infectivity

2009

ABSTRACT Several expressed sequence tags (ESTs) with homology to chitin deacetylase-like protein (CDA) were selected from a group of Helicoverpa armigera genes whose expression changed after infection with H. armigera single nucleopolyhedrovirus (HearNPV). Some of these ESTs coded for a midgut protein containing a chitin deacetylase domain (CDAD). The expressed protein, HaCDA5a, did not show chitin deacetylase activity, but it showed a strong affinity for binding to chitin. Sequence analysis showed the lack of any chitin binding domain, described for all currently known peritrophic membrane (PM) proteins. HaCDA5a has previously been detected in the H. armigera PM. Such localization, togethe…

BaculoviridaeExpressed Sequence TagvirusesMolecular Sequence DataImmunologyDown-RegulationChitinMothMothsSpodopteraSpodopteraHelicoverpa armigeraMicrobiologyAmidohydrolasesMicrobiologychemistry.chemical_compoundChitinDownregulation and upregulationChitin bindingVirologyAnimalsAmino Acid SequenceCells CulturedPhylogenyOligonucleotide Array Sequence AnalysisExpressed Sequence TagsAmidohydrolaseInfectivitySequence Homology Amino AcidbiologyAnimalOligonucleotide Array Sequence AnalysiGene Expression ProfilingfungiSequence Analysis DNAbiology.organism_classificationVirologyIsoenzymeGenome Replication and Regulation of Viral Gene ExpressionChitin deacetylaseIsoenzymeschemistryInsect ScienceBaculoviridaeSequence AlignmentJournal of Virology
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Reliability and Retention Study of Nanocrystal Cell Array

2002

We have studied nanocrystal memory arrays with 2.56 × 105 cells (256kb) in which Si nanocrystals have been obtained by CVD deposition on a 4nm tunnel oxide. The cells in the array are programmed and erased by electron tunneling through the SiO2 dielectric. We find that the threshold voltage distribution has little spread. In addition the arrays are also very robust with respect to drain stress and show good retention.

Reliability (semiconductor)Materials scienceCellular arrayNanocrystalNanotechnologyElectrical and Electronic EngineeringSafety Risk Reliability and QualitySettore ING-INF/01 - ElettronicaSettore FIS/03 - Fisica Della Materia
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Pre-production validation of the ATLAS level-1 calorimeter trigger system

2006

The Level-1 Calorimeter Trigger is a major part of the first stage of event selection for the ATLAS experiment at the LHC. It is a digital, pipelined system with several stages of processing, largely based on FPGAs, which perform programmable algorithms in parallel with a fixed latency to process about 300 Gbyte/s of input data. The real-time output consists of counts of different types of trigger objects and energy sums. Prototypes of all module types have been undergoing intensive testing before final production during 2005. Verification of their correct operation has been performed stand-alone and in the ATLAS test-beam at CERN. Results from these investigations will be presented, along …

PhysicsNuclear and High Energy PhysicsLarge Hadron ColliderCalorimeter (particle physics)Computer sciencePhysics::Instrumentation and Detectorsbusiness.industryReal-time computingATLAS experimentProcess (computing)Latency (audio)Calorimetermedicine.anatomical_structureBackplaneNuclear Energy and EngineeringAtlas (anatomy)Nuclear electronicsElectronic engineeringmedicineData pre-processingDetectors and Experimental TechniquesElectrical and Electronic EngineeringbusinessField-programmable gate arrayComputer hardwareIEEE Transactions on Nuclear Science
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FPGA-based concurrent watchdog for real-time control systems

2003

A straightforward and efficient implementation of a custom concurrent watchdog processor for real-time control systems is presented. Emphasis is given to the techniques used for on-line checking the main processor activity without adding overhead, and to the advantages of a field programmable gate array implementation.

Coprocessorbusiness.industryComputer scienceFPGA Fault tolerant systemsSettore ING-INF/01 - ElettronicaProgrammable logic arrayConcurrency controlReal-time Control SystemEmbedded systemControl systemOverhead (computing)Digital controlElectrical and Electronic EngineeringbusinessField-programmable gate arrayElectronics Letters
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Gray code for permutations with a fixed number of cycles

2007

AbstractWe give the first Gray code for the set of n-length permutations with a given number of cycles. In this code, each permutation is transformed into its successor by a product with a cycle of length three, which is optimal. If we represent each permutation by its transposition array then the obtained list still remains a Gray code and this allows us to construct a constant amortized time (CAT) algorithm for generating these codes. Also, Gray code and generating algorithm for n-length permutations with fixed number of left-to-right minima are discussed.

Golomb–Dickman constantPolynomial codeRestricted permutationsGenerating algorithms0102 computer and information sciences02 engineering and technology01 natural sciencesTheoretical Computer ScienceGray codeCombinatoricsPermutation[MATH.MATH-CO]Mathematics [math]/Combinatorics [math.CO]0202 electrical engineering electronic engineering information engineeringDiscrete Mathematics and CombinatoricsTransposition arrayComputingMilieux_MISCELLANEOUSMathematicsDiscrete mathematicsSelf-synchronizing codeAmortized analysisMathematics::CombinatoricsParity of a permutation020206 networking & telecommunicationsGray codes010201 computation theory & mathematicsConstant-weight codeMathematicsofComputing_DISCRETEMATHEMATICS
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miR-155 inhibition sensitizes CD4+ Th cells for TREG mediated suppression.

2009

BackgroundIn humans and mice naturally occurring CD4(+)CD25(+) regulatory T cells (nTregs) are a thymus-derived subset of T cells, crucial for the maintenance of peripheral tolerance by controlling not only potentially autoreactive T cells but virtually all cells of the adaptive and innate immune system. Recent work using Dicer-deficient mice irrevocably demonstrated the importance of miRNAs for nTreg cell-mediated tolerance.Principal findingsDNA-Microarray analyses of human as well as murine conventional CD4(+) Th cells and nTregs revealed a strong up-regulation of mature miR-155 (microRNA-155) upon activation in both populations. Studying miR-155 expression in FoxP3-deficient scurfy mice …

CD4-Positive T-LymphocytesScienceImmunology/ImmunomodulationBiologyModels BiologicalT-Lymphocytes RegulatoryImmune tolerancemiR-155MiceDownregulation and upregulationImmune ToleranceAnimalsHumansIL-2 receptorOligonucleotide Array Sequence AnalysisMultidisciplinaryInnate immune systemGenetics and Genomics/Functional GenomicsQInterleukin-2 Receptor alpha SubunitRPeripheral toleranceFOXP3Forkhead Transcription FactorsTransfectionImmunity InnateCell biologyUp-RegulationKineticsMicroRNAsImmunologyImmunology/Immune ResponseMedicineGenetics and Genomics/Genetics of the Immune SystemResearch ArticlePLoS ONE
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Comprehensive analysis of interacting proteins and genome-wide location studies of the Sas3-dependent NuA3 histone acetyltransferase complex

2014

Highlights • We characterise Sas3p and Gcn5p active HAT complexes in WT and deleted TAP-strains. • We confirm that Pdp3p interacts with NuA3, histones and chromatin regulators. • Pdp3p MS-analysis reveals its phosphorylation, ubiquitination and methylation. • Sas3p can substitute Gcn5p in acetylation of histone H3K14 but not of H3K9. • Genome-wide profiling of Sas3p supports its involvement in transcriptional elongation.

nt nucleotidePTM post-translational modificationNuA3 histone acetyltransferase complexChIP-on-chip chromatin immunoprecipitation with genome-wide location arraysBiologyArticleGeneral Biochemistry Genetics and Molecular BiologyChromatin remodelingHistonesHistone H3NuA3 nucleosomal acetyltransferase of histone H3Histone H1Histone H2APdp3TAP–MS strategyHistone codelcsh:QH301-705.5TAP tandem affinity purificationGeneticsRNAPII RNA polymerase IIHistone acetyltransferaseWCE whole cell extractSAGA Spt-Ada-Gcn acetyltransferaseWT wild-typeChromatinYeastCell biologyChIP-on-chiplcsh:Biology (General)Histone methyltransferasebiology.proteinHAT histone acetyltransferaseTSS transcription start siteFEBS Open Bio
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Molecular mechanisms of sorafenib action in liver cancer cells.

2012

Sorafenib, a multikinase inhibitor, recently received FDA approval for the treatment of advanced hepatocellular carcinoma (HCC). However, as the clinical application of sorafenib evolves, there is increasing interest in defining the mechanisms underlying its anti-tumor activity. Considering that this specific inhibitor could target unexpected molecules depending on the biologic context, a precise understanding of its mechanism of action could be critical to maximize its treatment efficacy, while minimizing adverse effects. Two human HCC cell lines (HepG2 and Huh7), carrying different biological and genetic characteristics, were used in this study to examine the intracellular events leading …

SorafenibDNA ReplicationNiacinamideCarcinoma HepatocellularDNA RepairTranscription GeneticAngiogenesisCell SurvivalPyridinesApoptosisPharmacologyBiologysorafenib HCC mini-chromosome maintenance genes Dickkopf1 Harakiri Acheron/LARP6 YAP1 cell cycle microarray global gene expression analysisCell Line TumormedicineCell AdhesionHumansneoplasmsMolecular BiologyProtein Kinase InhibitorsCell ProliferationYAP1Neovascularization PathologicCell growthGene Expression ProfilingPhenylurea CompoundsBenzenesulfonatesCell CycleLiver NeoplasmsBiological TransportCell BiologyCell cycleSorafenibmedicine.diseasedigestive system diseasesMechanism of actionHepatocellular carcinomaProtein Biosynthesismedicine.symptomMitogen-Activated Protein KinasesLiver cancerDevelopmental Biologymedicine.drugSignal Transduction
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