Search results for "Arrow"
showing 3 items of 953 documents
Word Order Typology and the Minimalist Program: What Do Parameters Belong To?
2019
One of the problems related with the word order and word order typology is connected with derivation obtaining in the narrow syntax and the conditions responsible for the Full Interpretation requirement at LF as well as at PF. If it is assumed that linearization as defined in Kayne (1994) is the reflexion of the asymmetric character of syntax at PF, then it is worth analysing which properties of the syntactic derivation within the narrow syntax are reflected at PF and which configurations seen on the surface are the results of PF conditions. In other words it would be interesting to determine the boundary between the factors responsible for the configuration of syntactic constituents obtain…
Extracellular Vesicle microRNAs Contribute to the Osteogenic Inhibition of Mesenchymal Stem Cells in Multiple Myeloma
2020
Osteolytic bone disease is the major complication associated with the progression of multiple myeloma (MM). Recently, extracellular vesicles (EVs) have emerged as mediators of MM-associated bone disease by inhibiting the osteogenic differentiation of human mesenchymal stem cells (hMSCs). Here, we investigated a correlation between the EV-mediated osteogenic inhibition and MM vesicle content, focusing on miRNAs. By the use of a MicroRNA Card, we identified a pool of miRNAs, highly expressed in EVs, from MM cell line (MM1.S EVs), expression of which was confirmed in EVs from bone marrow (BM) plasma of patients affected by smoldering myeloma (SMM) and MM. Notably,we found that miR-129-5p, whic…
Rules of Engagement: Family Rules on Young Children’s Access to and Use of Technologies
2018
This chapter reports on a study conducted in seven countries in which young children’s (aged under 8) digital practices in the home were examined. The study explored family practices with regard to access to and use of technologies, tracing the ways in which families managed risks and opportunities. Seventy families participated in the study, and interviews were undertaken with both parents and children, separately and together, in order to address the research aims. This chapter focuses on the data relating to parental mediation of young children’s digital practices. Findings indicate that parents used a narrow range of strategies in comparison to parents of older children, primarily becau…