Search results for "Association."
showing 10 items of 1723 documents
Physical Activity and Academic Performance: Genetic and Environmental Associations
2019
Introduction Physical activity and academic performance are believed to be associated. Though both traits are partially heritable, it remains unclear whether these traits also share a genetic and/or environmental background in common. We aimed to examine to what extent leisure time physical activity and academic performance share genetic and environmental effects from early adolescence to young adulthood. Methods Participants were Finnish twins (2543-2693 individuals/study wave) who reported their leisure-time physical activity at ages 12, 14, 17, and 24 yr. Academic performance was assessed with teacher-reported grade point averages at ages 12 and 14 yr and by self-reported educational lev…
Childhood gene-environment interactions and age-dependent effects of genetic variants associated with refractive error and myopia: The CREAM Consorti…
2018
Myopia, currently at epidemic levels in East Asia, is a leading cause of untreatable visual impairment. Genome-wide association studies (GWAS) in adults have identified 39 loci associated with refractive error and myopia. Here, the age-of-onset of association between genetic variants at these 39 loci and refractive error was investigated in 5200 children assessed longitudinally across ages 7-15 years, along with gene-environment interactions involving the major environmental risk-factors, nearwork and time outdoors. Specific variants could be categorized as showing evidence of: (a) early-onset effects remaining stable through childhood, (b) early-onset effects that progressed further with i…
The Protective Role of Prosocial Behaviors on Antisocial Behaviors: The Mediating Effects of Deviant Peer Affiliation
2014
Prosocial behaviors, actions intended to help others, may serve a protective function against association with deviant peers and subsequent delinquent and antisocial behaviors. The present study examined the relations among specific types of prosocial behaviors, deviant peer affiliation, and delinquent and aggressive behaviors. Six hundred and sixty-six adolescents (46% girls; M age = 15.33, SD = .47) from Valencia, Spain completed questionnaires of prosocial behaviors, affiliation with deviant peers, antisocial behaviors, and aggression. Results showed that antisocial behaviors were negatively related only to specific forms of prosocial behaviors. Further analyses showed that deviant peer …
Association between Life Skills and Academic Performance in Adolescents in the Autonomous Community of Aragon (Spain).
2021
Background: Learning and socio-emotional development is promoted through the creation and nurturing of an optimal school climate. This study aims to analyze the relationship between life skills and academic performance in a large sample of adolescents from the autonomous community of Aragón (Spain). Methods: A cross-sectional study was conducted on the life skills and academic performance of a sample of 7th and 8th grade middle school students during the academic year 2018–2019. A sample of 43 middle schools were randomly selected
Depression and workaholism in undergraduates: Examining gender as a moderator
2021
Introduction: This study aims to examine the association between depression and workaholism among university students. Methods: Participants were 182 undergraduates at a large university in the South of Poland, aged between 20–28 years old (M = 22.17, SD = 1.39), including 102 women (56%). The cross-sectional study used the Beck Depression Inventory (BDI) and the Work Addiction Risk Test (WART). Results: This study shows that depression and workaholism levels are significantly lower in Physical Education students than other faculties' students. Gender moderates the relationship between workaholism and depression. Women demonstrate a stronger association between depression and workaholism th…
Association Between the HLA-A2 Allele and Alzheimer Disease
2006
In the elderly, the most common cause of dementia is Alzheimer disease (AD), which is responsible for the age-related progressive neurodegenerative inflammatory condition mediated by the disease. It has been seen that several genetic and environmental factors are involved in AD onset. Epidemiologic data suggest that some genetic determinants of AD might reside in those polymorphisms that regulate immune inflammatory responses, such as the major histocompatibility complex (MHC). Therefore, several MHC polymorphisms have been in the spotlight of a large number of AD association studies. A possible association of HLA-A2 allele with increased susceptibility to AD has been the subject of debate …
Association between food insecurity and fall-related injury among adults aged ≥65 years in low- and middle-income countries: The role of mental healt…
2021
Purpose:\ud \ud We investigated the association between food insecurity and fall-related injury among older adults from six low- and middle-income countries (LMICs), and the extent to which this association is mediated by mental health.\ud \ud Methods:\ud \ud Cross-sectional, community-based, nationally representative data from the WHO Study on global AGEing and adult health (SAGE) were analyzed. Past 12-month food insecurity was assessed with two questions on frequency of eating less and hunger due to lack of food. Fall-related injury referred to those that occurred in the past 12 months. Multivariable logistic regression analysis and mediation analysis were conducted to assess association…
Association of childhood adversities and home atmosphere with functioning in old age: the Helsinki birth cohort study
2019
Objectivechildhood adversities have been linked with adverse health outcomes, but less is known about the long-term consequences of childhood home atmosphere. We investigated whether childhood adversities and home atmosphere were associated with physical and mental functioning in older age.Methodsin the Helsinki Birth Cohort Study 2003, participants born in the year 1934–44 had data available on nine childhood home atmosphere items, e.g. whether it was supportive and warm (sum score ranged between 0 and 36, higher score indicating better atmosphere), and nine childhood adversities, e.g. unemployment and divorce (sum score 0–9, coded into no; one; and two or more adversities) assessed in 200…
CHCH10 mutations in an Italian cohort of familial and sporadic amyotrophic lateral sclerosis patients
2015
Mutations in CHCHD10 have recently been described as a cause of frontotemporal dementia (FTD) comorbid with amyotrophic lateral sclerosis (ALS). The aim of this study was to assess the frequency and clinical characteristics of CHCHD10 mutations in Italian patients diagnosed with familial (n= 64) and apparently sporadic ALS (n= 224). Three apparently sporadic patients were found to carry c.100C>T (p.Pro34Ser) heterozygous variant in the exon 2 of CHCHD10. This mutation had been previously described in 2 unrelated French patients with FTD-ALS. However, our patients had a typical ALS, without evidence of FTD, cerebellar or extrapyramidal signs, or sensorineural deficits. We confirm that CHC…
Parental effects on offspring longevity--evidence from 17th to 19th century reproductive histories.
2004
Family studies provide support for a modest genetic influence on offspring life span, although the magnitude of these correlations is small.The study aimed to clarify the relative contributions of parental age at birth and overall parental longevity on offspring lifespan, and to identify the biological and cultural mechanisms.Information was derived from two village genealogies (1650-1927) encompassing 9979 births (5315 males, 4664 females). Data selection was guided by the inclusion of information about parental age at birth and lifespan, offspring lifespan and cohort-specific life expectancy.Parental age at reproduction displayed a negative association with offspring survivability, which …