Search results for "Automation"

showing 10 items of 1181 documents

Can We Study Autonomous Driving Comfort in Moving-Base Driving Simulators? A Validation Study.

2016

Objective: To lay the basis of studying autonomous driving comfort using driving simulators, we assessed the behavioral validity of two moving-base simulator configurations by contrasting them with a test-track setting. Background: With increasing level of automation, driving comfort becomes increasingly important. Simulators provide a safe environment to study perceived comfort in autonomous driving. To date, however, no studies were conducted in relation to comfort in autonomous driving to determine the extent to which results from simulator studies can be transferred to on-road driving conditions. Method: Participants ( N = 72) experienced six differently parameterized lane-change and de…

AdultMaleEngineeringValidation studyAutomobile DrivingInjury controlAccident preventionAccelerationPoison controlHuman Factors and ErgonomicsVirtual realityBehavioral NeuroscienceAutomationYoung Adult0502 economics and businessDriving simulationHumans0501 psychology and cognitive sciencesComputer Simulation050107 human factorsApplied PsychologySimulation050210 logistics & transportationbusiness.industry05 social sciencesHuman factors and ergonomicsReproducibility of ResultsEquipment DesignMiddle AgedResearch DesignFemalebusinessHuman factors
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Automatic algorithm for monitoring systolic pressure variation and difference in pulse pressure.

2009

BACKGROUND: Difference in pulse pressure (dPP) reliably predicts fluid responsiveness in patients. We have developed a respiratory variation (RV) monitoring device (RV monitor), which continuously records both airway pressure and arterial blood pressure (ABP). We compared the RV monitor measurements with manual dPP measurements. METHODS: ABP and airway pressure (PAW) from 24 patients were recorded. Data were fed to the RV monitor to calculate dPP and systolic pressure variation in two different ways: (a) considering both ABP and PAW (RV algorithm) and (b) ABP only (RV(slim) algorithm). Additionally, ABP and PAW were recorded intraoperatively in 10-min intervals for later calculation of dPP …

AdultMaleFluid responsivenessBlood PressureAutomationMonitoring IntraoperativeAbdomenMedicineHumansIn patientPulseAgedObserver VariationBlood Volumebusiness.industryAirway ResistanceLimits of agreementReproducibility of ResultsMiddle AgedReference StandardsPulse pressureAnesthesiology and Pain MedicineBlood pressureData Interpretation StatisticalRespiratory MechanicsFemalebusinessAlgorithmAlgorithmsAnesthesia and analgesia
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Comparative Evaluation of Three Automated Systems for DNA Extraction in Conjunction with Three Commercially Available Real-Time PCR Assays for Quanti…

2011

ABSTRACT Limited data are available on the performance of different automated extraction platforms and commercially available quantitative real-time PCR (QRT-PCR) methods for the quantitation of cytomegalovirus (CMV) DNA in plasma. We compared the performance characteristics of the Abbott mSample preparation system DNA kit on the m24 SP instrument (Abbott), the High Pure viral nucleic acid kit on the COBAS AmpliPrep system (Roche), and the EZ1 Virus 2.0 kit on the BioRobot EZ1 extraction platform (Qiagen) coupled with the Abbott CMV PCR kit, the LightCycler CMV Quant kit (Roche), and the Q-CMV complete kit (Nanogen), for both plasma specimens from allogeneic stem cell transplant (Allo-SCT) …

AdultMaleMicrobiology (medical)BiologyReal-Time Polymerase Chain Reactionmedicine.disease_causeVirusAutomationchemistry.chemical_compoundVirologymedicineHumansTransplantation HomologousViremiaAgedTransplantationCytomegalovirusMiddle AgedViral LoadDNA extractionVirologyMolecular biologyTransplantationReal-time polymerase chain reactionchemistryCytomegalovirus InfectionsDNA ViralFemaleStem cellViral loadDNAStem Cell Transplantation
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Automated Determination of Ziprasidone by HPLC With Column Switching and Spectrophotometric Detection

2005

An isocratic high-performance liquid chromatography (HPLC) method with column switching and ultraviolet (UV) detection is described for quantitative analysis of the new antipsychotic drug ziprasidone. After centrifugation of serum or plasma samples and addition of fluperlapine as internal standard, the samples were injected into the HPLC system. On-line sample clean-up was conducted on a column (10 x 4.0 mm ID) filled with silica C8 material (20-microm particle size) using 8% (vol/vol) acetonitrile in deionized water as eluent. Ziprasidone was eluted and separated on ODS Hypersil C18 material (5 microm; column size 250 x 4.6 mm ID) using acetonitrile-water-tetramethylethylendiamine (50:49.6…

AdultMaleTime FactorsSensitivity and SpecificityHigh-performance liquid chromatographyDrug Administration SchedulePiperazinesAutomationBenzodiazepinesBlood serumColumn chromatographymedicineHumansPharmacology (medical)ZiprasidoneClozapineChromatography High Pressure LiquidPharmacologyDetection limitChromatographymedicine.diagnostic_testElutionChemistryReproducibility of ResultsMiddle AgedThiazolesOlanzapineSpectrophotometryTherapeutic drug monitoringSchizophreniaFemaleDrug MonitoringQuantitative analysis (chemistry)medicine.drugTherapeutic Drug Monitoring
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Diagnostic accuracy of a fully automated multiplex celiac disease antibody panel for serum and plasma.

2019

Abstract Background An automated multiplex platform using capillary blood can promote greater throughput and more comprehensive studies in celiac disease (CD). Diagnostic accuracy should be improved using likelihood ratios for the post-test probability of ruling-in disease. Methods The Ig_plex™ Celiac Disease Panel on the sqidlite™ automated platform measured IgA and IgG antibodies to tTG and DGP in n = 224 CD serum or plasma samples. Diagnostic accuracy metrics were applied to the combined multiplex test results for several CD populations and compared to conventional single antibody ELISA tests. Results With multiple positive antibody results, the post-test probability for ruling-in untrea…

AdultMalemedicine.medical_specialtyAdolescentClinical BiochemistryDiagnostic accuracyEnzyme-Linked Immunosorbent AssayDiseaseGastroenterology03 medical and health sciencesAutomationYoung Adult0302 clinical medicineCapillary PlasmaPredictive Value of TestsInternal medicineBiopsymedicineHumansMultiplex030212 general & internal medicineChildAutoantibodiesbiologymedicine.diagnostic_testbusiness.industryBiochemistry (medical)General MedicineMiddle AgedResponse to treatmentCeliac DiseaseFully automatedChild Preschoolbiology.protein030211 gastroenterology & hepatologyFemaleAntibodybusinessBlood Chemical AnalysisClinical chemistry and laboratory medicine
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Microcentrifuge or Automated Hematological Analyzer to Assess Hematocrit in Exercise? Effect on Plasma Volume Loss Calculations

2016

The assessment of plasma volume loss (∆PV) induced by exercise can be estimated from changes in hematocrit (Htc) and hemoglobin (Hb), and it is essential when investigating the metabolic or biologic response to exercise of circulating biomarkers. We aimed to ascertain whether the estimation of ∆PV may differ when Hb and Htc are determined by automated hematological analyzer (AHA) versus manual methods. Twenty-five healthy male subjects performed a maximal running incremental exercise. Blood samples were taken before exercise, immediately after exercise, and after a 30-min recovery. Hb and Htc (Htc-AHA) were determined by an AHA. Htc was also determined by microcentrifugation (Htc-M). The ∆P…

AdultMalemedicine.medical_specialtySpectrum analyzerSysmexAnalytical chemistryCentrifugationHematocritPlasma volumeIncremental exerciseHemoglobinsYoung Adult03 medical and health sciences0302 clinical medicineInternal medicinemedicineHumanshemoconcentrationhealth care economics and organizationsplasma volumeAutomation LaboratoryexerciseBiologic responsemedicine.diagnostic_testChemistryDill and Costill equation030229 sport sciencesMiddle AgedhemoglobinHemoconcentrationDill and Costill equation; Sysmex; exercise; hemoconcentration; hemoglobin; plasma volumeHealthy Volunteersdigestive system diseasesComputer Science ApplicationsMedical Laboratory TechnologyCirculating biomarkersHematocritCardiologyHemoglobinBiomarkers030215 immunologySLAS Technology
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Effect of changing pulse rate on profile parameters of perceptual thresholds and loudness comfort levels and relation to ECAP thresholds in recipient…

2010

Abstract: The Nucleus CI24RE Freedom device offers higher stimulation rates and lower noise levels in action potential measurements (ECAPs) than previous devices. A study including ten European implant teams showed that the effect of changes in rate from 250 to 3500 pulses per second on tilt and curvature of the T and C profiles is insignificant. When changing rate one may change the levels at all electrodes by the same amount. Using an automated procedure ECAPs could be measured quickly and reliably at a noise level of only 1 μV. However, this did not result in improved correlations between the tilt and curvature parameters of the ECAP profiles and those of the T and C profiles. Average C …

AdultPulse repetition frequencyLinguistics and Languagemedicine.medical_specialty3616 Speech and HearingLoudness Perceptionmedia_common.quotation_subjectAction PotentialsDifferential Threshold610 Medicine & health10045 Clinic for OtorhinolaryngologyStimulus (physiology)AudiologyCurvatureLanguage and LinguisticsLoudnessAutomationYoung AdultSpeech and HearingPerceptionmedicineHumansComfort levels1203 Language and LinguisticsAgedmedia_commonMathematicsPrincipal Component AnalysisAuditory ThresholdMiddle AgedElectric Stimulation3310 Linguistics and LanguageCochlear Implantsmedicine.anatomical_structurePulse rateAuditory PerceptionHuman medicineNoiseNucleus
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A fully automated system for the evaluation of masseter silent periods.

1997

Exteroceptive suppression of masseter muscle activity, 'masseter inhibitory reflex', comprises one or 2 silent periods (SP1 and SP2) interrupting the voluntary activation. The main problem when evaluating exteroceptive suppression is the lack of an objective and precise measure for the onset and end of the silent period which so far has not been overcome by various automated systems. We describe a new fully automated system for determining the onset and end of the masseter silent period. The decision approach is essentially based upon deterministic properties of median filters which are used to partition the local variances of the EMG traces into constant segments and edges between them. Th…

Adultmedicine.medical_specialtyAnalysis of Variancemedicine.diagnostic_testAdolescentComputer scienceElectromyographyMasseter MuscleGeneral NeuroscienceComputer aidElectromyographyAudiologyMasseter muscleAutomationFully automatedReference ValuesHealthy volunteersmedicineReflexHumansSilent periodNeurology (clinical)Decision processElectroencephalography and clinical neurophysiology
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A Bio-Inspired Cognitive Agent for Autonomous Urban Vehicles Routing Optimization

2017

Autonomous urban vehicle prototypes are expected to be efficient even in not explicitly planned circumstances and dynamic environments. The development of autonomous vehicles for urban driving needs real-time information from vehicles and road network to optimize traffic flows. In traffic agent-based models, each vehicle is an agent, while the road network is the environment. Cognitive agents are able to reason on the perceived data, to evaluate the information obtained by reasoning, and to learn and respond, preserving their self-sufficiency, independency, self-determination, and self-reliance. In this paper, a bio-inspired cognitive agent for autonomous urban vehicles routing optimization…

Agent behaviorComputer scienceProcess (engineering)Functional featuresDistributed computingMetabolic network020206 networking & telecommunications02 engineering and technologyvehicular ad hoc networks (VANETs)Urban roadCognitive agentArtificial IntelligenceAutonomous urban vehicles routing optimization0202 electrical engineering electronic engineering information engineering020201 artificial intelligence & image processingRouting (electronic design automation)cellular metabolismSoftwareSimulationCell survivalcognitive agentIEEE Transactions on Cognitive and Developmental Systems
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Computational Analysis of the Active Control of Incompressible Airfoil Flutter Vibration Using a Piezoelectric V-Stack Actuator

2021

The flutter phenomenon is a potentially destructive aeroelastic vibration studied for the design of aircraft structures as it limits the flight envelope of the aircraft. The aim of this work is to propose a heuristic design of a piezoelectric actuator-based controller for flutter vibration suppression in order to extend the allowable speed range of the structure. Based on the numerical model of a three degrees of freedom (3DOF) airfoil and taking into account the FEM model of a V-stack piezoelectric actuator, a filtered PID controller is tuned using the population decline swarm optimizer PDSO algorithm, and gain scheduling (GS) of the controller parameters is used to make the control adapti…

Airfoil020301 aerospace & aeronautics0209 industrial biotechnologyactive flutter suppressionV-stack actuatorComputer sciencePID controller02 engineering and technologylcsh:QC1-999Vibrationpopulation decline swarmoptimizer020901 industrial engineering & automationGain scheduling0203 mechanical engineeringFlight envelopeControl theoryFluttergain schedulingpopulation decline swarm optimizerSettore ING-IND/04 - Costruzioni E Strutture AerospazialiActuatorlcsh:PhysicsVibration
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