Search results for "Autor"

Indicaciones autorizadas en España de los fármacos antiosteoporóticos

2005

Introduccion En Espana hay unos 3 millones de personas > 50 anos con osteoporosis, de las que dos tercios son mujeres 1 . En adultos jovenes se ha estimado una incidencia de 4,1 por 100.000 personas/ano 2 . En varones ocurren cerca del 30% de las fracturas de cadera. Se estima que el 29% de los varones > 60 anos que no reciben tratamiento preventivo tendra una fractura; asimismo, la morbilidad tras fractura por fragilidad es tan elevada en varones como en mujeres y la mortalidad al ano de presentar una fractura de cadera es aproximadamente el doble en varones que en mujeres 3 . Ademas, el 7,5% de la poblacion adulta recibe tratamiento oral con glucocorticoides y su riesgo relativo de fractu…

Sevoflurane Impairs Cerebral Blood Flow Autoregulation in Rats: Reversal by Nonselective Nitric Oxide Synthase Inhibition

2005

UNLABELLED In this study, we investigated the effects of 1.0 and 2.0 minimum alveolar anesthetic concentration (MAC) sevoflurane on cerebral blood flow (CBF) autoregulation before and after nonselective inhibition of nitric oxide (NO) synthase in rats. Rats were randomly assigned as follows: Group 1 (n = 8): 1.0 MAC sevoflurane; Groups 2 and 3 (n = 8 per group): 2.0 MAC sevoflurane. Assessment of autoregulation within a mean arterial blood pressure range of 140-60 mm Hg was performed by graded hemorrhage before and after administration of l-arginine methyl ester (l-NAME, 30 mg/kg IV, Groups 1 and 2) or during hypocapnia (Group 3). In 10 additional animals, brain tissue NO(2)(-) concentratio…

Revisió. 2018 - 'Metodologies Musicals'-segles XX i XXI.

2018

Revisió i afegiments de les velles metodologies musicals (arxiu ja enviat al 2016 a Roderic). Canvis estructurals diversos i desenvolupament de metodologies ja esmentades abans. Dirigit a alumnes de l'assignatura 'Didàctica de la Música' de la Facultat de Magisteri. New revision and updating of the old music methodologies file. Various changes in the structure and development of the file directed to students of Musical Training Teaching and scholars of the topic.

Specific DNA probes to detect Escherichia coli strains producing cytotoxic necrotising factor type 1 or type 2

1994

Cytotoxic necrotising factors type 1 (CNF1) and type 2 (CNF2) are produced by many Escherichia coli strains isolated from man and animals with intestinal or extra-intestinal colibacillosis. In most laboratories, CNF-producing strains are detected by a cell cytotoxicity assay and confirmed with a neutralisation assay or a mouse footpad assay. In this study, we sought to determine whether DNA probes could detect clinical isolates of E. coli producing CNF2 or CNF1, or both, without the need for cell cultures or animal assays. Two internal fragments of the gene encoding CNF2 were used as DNA probes: a 875-bp XhoI-PstI DNA fragment and an adjacent 335-bp PstI-ClaI fragment. A positive response w…

Práctica Española en materia de Tratados Internacionales correspondiente al año 1997

2018

El presente trabajo analiza cuatro aspectos correspondientes a la práctica española sobre celebración de tratados internacionales durante el año 1997. Estos aspectos son: a) la tramitación parlamentaria de los tratados internacionales; b) la publicidad de los tratados; c) las alteraciones en el listado de Estados partes en los tratados internacionales en los que España es Estado parte; y d) una selección de las declaraciones oficiales relativas a tratados en los que España es Estado parte

Ripensare la modernità cinematografica. Il ragazzo con la bicicletta di Jean-Pierre e Luc Dardenne

2014

Inhibition of tumor lactate oxidation: consequences for the tumor microenvironment.

2011

Abstract Background and purpose Tumor cells are recognized as being highly glycolytic. However, recently it was suggested that lactate produced in hypoxic tumor areas may be taken up by the monocarboxylate transporter MCT1 and oxidized in well-oxygenated tumor parts. Furthermore, it was shown that inhibition of lactate oxidation using the MCT1 inhibitor α-cyano-hydroxycinnamate (CHC) can radio-sensitize tumors possibly by forcing a switch from lactate oxidization to glycolysis in oxygenated cells, which in turn improves tumor oxygenation and indirectly kills radio-resistant hypoxic tumor cells from glucose starvation. Material and methods To provide direct evidence for the existence of a ta…

Efficient Computation of Multiscale Entropy over Short Biomedical Time Series Based on Linear State-Space Models

2017

The most common approach to assess the dynamical complexity of a time series across multiple temporal scales makes use of the multiscale entropy (MSE) and refined MSE (RMSE) measures. In spite of their popularity, MSE and RMSE lack an analytical framework allowing their calculation for known dynamic processes and cannot be reliably computed over short time series. To overcome these limitations, we propose a method to assess RMSE for autoregressive (AR) stochastic processes. The method makes use of linear state-space (SS) models to provide the multiscale parametric representation of an AR process observed at different time scales and exploits the SS parameters to quantify analytically the co…

Multivariate autoregressive model with instantaneous effects to improve brain connectivity estimation

2009

Imputation Strategies for Missing Data in Environmental Time Series for An Unlucky Situation

2005

After a detailed review of the main specific solutions for treatment of missing data in environmental time series, this paper deals with the unlucky situation in which, in an hourly series, missing data immediately follow an absolutely anomalous period, for which we do not have any similar period to use for imputation. A tentative multivariate and multiple imputation is put forward and evaluated; it is based on the possibility, typical of environmental time series, to resort to correlations or physical laws that characterize relationships between air pollutants.