Search results for "B12"

Una nueva mirada al informe de Ley Agraria de Jovellanos doscientos años después

1995

Editada en la Fundación Empresa Pública Con motivo del bicentenario (1795-1995) de la publicación de lnforme de Ley Agraria de Jovellanos se presenta una visión retrospectiva de esa obra ya clásica del pensamiento español incluyendo un repaso de sus múltiples y desacordes intérpretes modernos y un análisis del interior del texto e incluso del título. Se concluye insistiendo en la plena inserción del Informe en la tradición ilustrada española, en que los usuales calificativos de mercantilista, liberal smithniano o fisiócrata son inadecuados y en que es preciso restituir la obra y su autor a su tiempo. Publicado

Maternal vitamin deficiency mimicking multiple acyl-CoA dehydrogenase deficiency on newborn screening

2021

Abstract Background In infancy multiple acyl-CoA dehydrogenase deficiency (MADD) is commonly a severe inherited metabolic disease caused by genetic defects in electron transfer flavoprotein (ETF) or ETF ubiquinone oxidoreductase. Both enzymes require flavin adenine dinucleotide (FAD) as a cofactor. Riboflavin (vitamin B2) is a precursor in the synthesis of FAD. MADD can be detected by newborn screening (NBS) based on elevation of multiple acylcarnitines. Methods We present the results of two children whose NBS results and subsequent confirmatory testing resulted in a suspected diagnosis of MADD. In parallel in both children vitamin B12 deficiency was detected. Results Biochemical profiles n…

Clinical and Brain Imaging Findings in a Child with Vitamin B12 Deficiency

2021

Vitamin B12 (Vit-B12) deficiency is a rare and treatable cause of failure to thrive and delayed development in infants who are exclusively breastfed. Apart from genetic causes, it can be related to a malabsorption syndrome or when the mother follows a strict vegetarian or vegan diet, causing a low hepatic storage of Vit-B12 in the infant at birth. As the neurological symptoms are nonspecific, a brain magnetic resonance imaging (MRI) exam is usually performed to rule out primary causes of neurodevelopmental delay. Findings related to brain atrophy are usually observed. A favorable response is achieved with Vit-B12 therapy, and neurological symptoms dramatically improve within a few days afte…

Health Outcomes of Infants with Vitamin B12 Deficiency Identified by Newborn Screening and Early Treated

2021

Objective To evaluate the clinical outcomes at age 1.5 ± 0.5 years of infants with vitamin B12 deficiency identified by newborn screening (NBS). Study design Prospective multicenter observational study on health outcomes of 31 infants with vitamin B12 deficiency identified by NBS. Neurodevelopment was assessed by the Denver Developmental Screening Test. Results In 285 862 newborns screened between 2016 and 2019, the estimated birth prevalence of vitamin B12 deficiency was 26 in 100 000 newborns, with high seasonal variations (lowest in summer: 8 in 100 000). Infants participating in the outcome study (N = 31) were supplemented with vitamin B12 for a median (range) of 5.9 (1.1-16.2) months. …

Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight

2021

From 1985 to 2016, the prevalence of underweight decreased, and that of obesity and severe obesity increased, in most regions, with significant variation in the magnitude of these changes across regions. We investigated how much change in mean body mass index (BMI) explains changes in the prevalence of underweight, obesity, and severe obesity in different regions using data from 2896 population-based studies with 187 million participants. Changes in the prevalence of underweight and total obesity, and to a lesser extent severe obesity, are largely driven by shifts in the distribution of BMI, with smaller contributions from changes in the shape of the distribution. In East and Southeast Asia…

The Fatou coordinate for parabolic Dulac germs

2017

We study the class of parabolic Dulac germs of hyperbolic polycycles. For such germs we give a constructive proof of the existence of a unique Fatou coordinate, admitting an asymptotic expansion in the power-iterated log scale.

Could Themis be the Deity who «Steers» Parmenides’ Cosmos?

2021

In this paper I will investigate the identity of the daímōn introduced by Parmenides in B12, 3 DK, the deity “who steers all things”. The importance of this deity is not adequately reflected in ancient doxography but in recent decades many scholars have reconsidered its role. I argue that in Parmenides’ poem this daímōn may play a relevant role in connecting the theological, ontological and cosmological planes. My purpose is to provide enough arguments for the hypothesis that the daímōn may be the same goddess, Themis, who in the proem (B1, 28) is paired with Dike as a guide for Parmenides to the theá who will reveal to him the truth of tò eón, and in the part of the poem called alḗtheia (B…

Vitamin B12 deficiency with multiple sclerosis-like neurological clinical framework.

2012

Supplémentation en acide folique, vitamines B6 et B12 et incidence de la DMLA

2010

National audience

Adequate vitamin B12 and folate status of Norwegian vegans and vegetarians

2022

AbstractPlant-based diets may increase the risk of vitamin B12 deficiency due to limited intake of animal-source foods, while dietary folate increases when adhering to plant-based diets. In this cross-sectional study, we evaluated the B12 and folate status of Norwegian vegans and vegetarians using dietary B12 intake, B12 and folic acid supplement use, and biomarkers (serum B12 (B12), plasma total homocysteine (tHcy), plasma methylmalonic acid (MMA) and serum folate). Vegans (n 115) and vegetarians (n 90) completed a 24-h dietary recall and a FFQ and provided a non-fasting blood sample. cB12, a combined indicator for evaluation of B12 status, was calculated. B12 status was adequate in both v…