Search results for "B1"
showing 10 items of 1109 documents
RTS2 - the Remote Telescope System
2010
RTS2 is an open source observatory manager. It was written from scratch in the C++ language, with portability and modularity in mind. Its driving requirements originated from quick follow-ups of Gamma Ray Bursts. After some years of development it is now used to carry tasks it was originally not intended to carry. This article presents the current development status of the RTS2 code. It focuses on describing strategies which worked as well as things which failed to deliver expected results. Copyright © 2010 Petr Kubánek.
Pharmacological blockade of the fatty acid amide hydrolase (FAAH) alters neural proliferation, apoptosis and gliosis in the rat hippocampus, hypothal…
2015
Endocannabinoids participate in the control of neurogenesis, neural cell death and gliosis. The pharmacological effect of the fatty acid amide hydrolase (FAAH) inhibitor URB597, which limits the endocannabinoid degradation, was investigated in the present study. Cell proliferation (phospho-H3(+) or BrdU(+) cells) of the main adult neurogenic zones as well as apoptosis (cleaved caspase-3(+)), astroglia (GFAP(+)), and microglia (Iba1(+) cells) were analyzed in the hippocampus, hypothalamus and striatum of rats intraperitoneally treated with URB597 (0.3 mg/kg/day) at one dose/4-days resting or 5 doses (1 dose/day). Repeated URB597 treatment increased the plasma levels of the N-acylethanolamine…
Multimessenger Binary Mergers Containing Neutron Stars: Gravitational Waves, Jets, and γ-Ray Bursts
2021
Neutron stars (NSs) are extraordinary not only because they are the densest form of matter in the visible Universe but also because they can generate magnetic fields ten orders of magnitude larger than those currently constructed on earth. The combination of extreme gravity with the enormous electromagnetic (EM) fields gives rise to spectacular phenomena like those observed on August 2017 with the merger of a binary neutron star system, an event that generated a gravitational wave (GW) signal, a short γ-ray burst (sGRB), and a kilonova. This event serves as the highlight so far of the era of multimessenger astronomy. In this review, we present the current state of our theoretical understand…
A Dirichlet problem for the Laplace operator in a domain with a small hole close to the boundary
2016
We study the Dirichlet problem in a domain with a small hole close to the boundary. To do so, for each pair $\boldsymbol\varepsilon = (\varepsilon_1, \varepsilon_2 )$ of positive parameters, we consider a perforated domain $\Omega_{\boldsymbol\varepsilon}$ obtained by making a small hole of size $\varepsilon_1 \varepsilon_2 $ in an open regular subset $\Omega$ of $\mathbb{R}^n$ at distance $\varepsilon_1$ from the boundary $\partial\Omega$. As $\varepsilon_1 \to 0$, the perforation shrinks to a point and, at the same time, approaches the boundary. When $\boldsymbol\varepsilon \to (0,0)$, the size of the hole shrinks at a faster rate than its approach to the boundary. We denote by $u_{\bolds…
Cannabinoid CB1 receptor activation modulates spontaneous contractile activity in mouse ileal longitudinal muscle.
2007
The purpose of the present study was to examine whether cannabinoid receptor agonists influence spontaneous contractile activity of longitudinal muscle in mouse ileum in vitro. Isolated segments of mouse ileum displayed spontaneous contractions with an amplitude and frequency of about 300 mg and 30 cpm, respectively. The endocannabinoid anandamide (1-100 microM), the selective cannabinoid CB(1) receptor agonist, ACEA (0.1 microM-10 microM), but not the selective cannabinoid CB(2) receptor agonist, JWH 133 (0.1 microM-10 microM), reduced in a concentration-dependent manner the spontaneous mechanical activity. The inhibitory effect consisted in a decrease of the mean amplitude of longitudinal…
The lie as epistemological principle
2015
La gestión de la existencia pasa por el empleo del mentir como herramienta clave en el uso cotidiano. La “utilidad” que de ello extrae el hombre es de una enorme variedad. Ha sido largo el tiempo en que la mentira ha quedado reducida a un mero problema moral, pero la verdadera cuestión por el mentir estriba en su estatus ontológico. Mentir –más concretamente: mentirse– es un modo de gestionar la peculiar existencia que nos ha sido dada
MTHFR 677C → T genotype modulates the effect of a 5-year supplementation with B-vitamins on homocysteine concentration: The SU.FOL.OM3 randomized con…
2018
Aims To study how MTHFR 677C→T genotype modulates the effect of supplementation with B-vitamins on total homocysteine (tHcy) and B-vitamin concentrations. Methods 2381 patients with a personal history of cardiovascular disease were randomly assigned to one of four groups: 1) B-vitamins alone (560 μg of 5-methyl-THF, 3 mg of vitamin B6 and 20 μg of vitamin B12), 2) n-3 fatty acids alone (600 mg of EPA and DHA in a 2:1 ratio), 3) B-vitamins and n-3 fatty acids, and 4) placebo. Participants were followed up for 4.7 years. At baseline and annually thereafter, biological parameters were assessed. Multivariate and linear mixed models were fit to study the interaction between B-vitamins and MTHFR …
Vizuālās atgādnes angļu valodas B1 līmeņa skolēniem individuāli pielāgota mācīšanās tempa atbalstam
2021
Kompetencēs balstīta izglītība pieprasa ņemt vērā daudzveidīgo skolēnu vajadzību un iepriekšējo zināšanu bāzi. Ir skaidrs, ka skolēni sasniedz prasmju meistarību atšķirīgos ātrumos. Pētījuma mērķis bija izpētīt, kā individuāli pielāgotu mācīšanās tempu var sekmēt ar vizuālo atgādņu izmantošanu B1 līmeņa angļu valodas apguvē. Darbības pētījums tika īstenots caur vairākkārtējiem vizuālo atgādņu uzlabojumiem, ņemot vērā skolēnu un skolotāju sniegto atgriezenisko saiti. Pētījums apstiprināja, ka vizuālās atgādnes ietekmē skolotāja kompetenci vadīt mācību stundas, nodrošinot individuāli pielāgota mācību tempa atbalstu. Patstāvīgs darbs ar mācību materiāliem uzlabo skolēna akadēmiskos sasniegumus…
Introdução à tradução: sobre a formulação do conceito crítico de liberdade e de autonomia da vontade
2012
O que o leitor tera na sequencia e a traducao de uma pequena selecao de reflexoes de Immanuel Kant sobre filosofia moral redigidas, em sua grande maioria, ao longo “decada silenciosa” de 1770. A escolha dos fragmentos, retirados dos volumes XVII, XVIII (Reflexoes sobre Metafisica) e XIX (Reflexoes sobre Filosofia Moral) da edicao da Academia, 1 foi motivada por um interesse interpretativo de fundo: a defesa de uma descontinuidade da filosofia moral kantiana na passagem do periodo pre-critico para o critico. Com isso se sugere que a existencia de uma concepcao critica da liberdade e a formulacao do principio da autonomia da vontade como um principio supremo da moralidade apenas se tornaram p…