Search results for "BARD"

showing 10 items of 208 documents

Steroidal saponins from the roots of Smilax aspera subsp. mauritanica

2008

Two new steroidal saponins (1, 2) were isolated from the roots of Smilax aspera subsp. mauritanica (POIR.) ARCANG. (Liliaceae), together with the known curillin G (3), asparagoside E (4), asparoside A (5), asparoside B (6) and the phenolic compound resveratrol (7). Their structures were established mainly on the basis of 600 MHz 2D-NMR spectral data. 3 exhibited antifungal activity against the human pathogenic yeasts Candida albicans, C. glabrata and C. tropicalis (minimum inhibitory concentrations of 25, 25 and 50 microg/ml, respectively) whereas the other compounds were inactive.

AntifungalSpectrometry Mass Electrospray IonizationAntifungal AgentsMagnetic Resonance SpectroscopySpectrophotometry Infraredmedicine.drug_classMolecular Sequence DataPharmaceutical ScienceMicrobial Sensitivity TestsSpectrometry Mass Fast Atom BombardmentResveratrolPlant RootsAnalytical Chemistrychemistry.chemical_compoundDrug DiscoveryBotanymedicineCandida albicansSpectral dataSmilax asperaCandidaPharmacologybiologyTraditional medicineLiliaceaeHydrolysisOrganic ChemistryFungiGeneral ChemistryGeneral MedicineSaponinsbiology.organism_classificationKetoconazoleCarbohydrate SequenceComplementary and alternative medicinechemistrySmilaxMolecular MedicineSteroidsPlanta Medica
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Ocean-scale connectivity and life cycle reconstruction in a deep-sea fish

2014

Author's version of an article in the journal: Canadian Journal of Fisheries and Aquatic Sciences. Also available from the publisher at: http://dx.doi.org/10.1139/cjfas-2013-0343 As human exploration and harvesting moves to the high seas, ecological understanding of the deep sea has become a priority, especially in those commercially exploited species whose life cycle, habitat use, and demographic structure remain poorly understood. Here we combine otolith trace element and stable isotope analyses with microsatellite data to investigate population structure and connectivity in the migratory deep-sea black scabbardfish (Aphanopus carbo), sampled along a latitudinal gradient spanning much of …

Aphanopusgeographygeography.geographical_feature_categorybiologyEcologyContinental shelfSpecies distributionAquatic Sciencebiology.organism_classificationDeep seaBlack scabbardfishmedicine.anatomical_structureHabitatDeep sea fishmedicineEcology Evolution Behavior and SystematicsVDP::Agriculture and fishery disciplines: 900::Fisheries science: 920::Resource biology: 921OtolithCanadian Journal of Fisheries and Aquatic Sciences
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El miedo, arma política

1998

Arma políticaprofesionales del crimen políticoPoder económicoAutocraciasVidal-Beneyto JoséMiedo al trabajo-paroMIEDOPoblaciones civilesIrakTerrorismoPolíticaMatanzasRepresiones estatalesTerrorPoder políticoPublicaciones: Obra periodística: Columnas y artículos de opiniónCombate democráticoGuerra tecnológicaMiedo colectivoMiedo al presenteArgeliaEstructura psicosocialMuertosTerritorialidadMiedo políticoMiedo a uno mismoImpunidadMiedos de todos por todoMiedo al futuroCongoBombardeosMiedo a los demásMiedo al amor-sidaEspando disuasivoPoder simbólico
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El honor de la sociedad civil israeli

2002

AtentadosSociedad civil israelíPazVidal-Beneyto JoséPalestinaEstados UnidosRepresaliasAcciones pacíficasEjército israelíConsejo Palestino de Justicia y PazVerdugosGuerraPublicaciones: Obra periodística: Columnas y artículos de opiniónCONFLICTO PALESTINA-ISRAELBarbarieBombardeosUnión EuropeaJusticiaHonorVíctimasSegunda IntifadaIsraelDolorTerritorios ocupados
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Translational readthrough of ciliopathy genes BBS2 and ALMS1 restores protein, ciliogenesis and function in patient fibroblasts

2021

Abstract Background Ciliary dysfunction underlies a range of genetic disorders collectively termed ciliopathies, for which there are no treatments available. Bardet-Biedl syndrome (BBS) is characterised by multisystemic involvement, including rod-cone dystrophy and renal abnormalities. Together with Alstrom syndrome (AS), they are known as the ‘obesity ciliopathies’ due to their common phenotype. Nonsense mutations are responsible for approximately 11% and 40% of BBS and AS cases, respectively. Translational readthrough inducing drugs (TRIDs) can restore full-length protein bypassing in-frame premature termination codons, and are a potential therapeutic approach for nonsense-mediated ciliop…

BBS2AdultMaleMedicine (General)AdolescentNonsense mutationAminopyridinesCell Cycle ProteinsCiliopathiesGeneral Biochemistry Genetics and Molecular Biologychemistry.chemical_compoundR5-920AtalurenCiliogenesismedicineHumansReceptors SomatostatinBardet-Biedl SyndromeAlstrom SyndromeCells CulturedOxadiazolesbusiness.industryTumor Suppressor ProteinsTranslational readthroughRProteinsGeneral MedicineFibroblastsmedicine.diseaseNonsense suppressionCiliopathiesAtalurenCiliopathyALMS1chemistryCodon NonsenseAmlexanoxCancer researchMedicineBBS2businessAlström syndromeResearch PaperEBioMedicine
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Zvaigžņotā Debess: 2010/11, Ziema (210)

2010

Contents: “ZVAIGŅOTĀ DEBESS” FORTY YEARS AGO: Bursting Stars. J. Francman (abridged). Geodesists Help Renew the Spire of St. Peter’s Church. J. Klētnieks (abridged). DEVELOPMENTS in SCIENCE: The Solar Neutrino Problem. O. Smirnova. NEWS: At Last the Planet at the Star β Pictoris Is Imaged. A. Alksnis, Z. Alksne. SPACE RESEARCH and EXPLORATION: The Trail of an Asteroid Reveals a Recent Collision. A. Alksnis. INTERNATIONAL YEAR of ASTRONOMY 2009: International Year of Astronomy 2009 in Philately. The Rest of the World except Series EUROPA (concluded). J. Limansky. ACADEMIC STAFF of the UNIVERSITY of LATVIA: Assistant Professor in Physics Ojārs Šmits (24.04.1930.-14.03.1993.) of the Latvian Un…

Baldones skolēni Maskavā un LisabonāStarptautiskie kosmiskie lidojumi – pastmarkasPubliskie saules pulksteņi LatvijāAlfonam Apinim – 100Vistālākā galaktikaEmanuels GrinbergsJupitera bombardēšana – amatieru novērojumiPlanētu redzamības kompleksā diagramma 2011J.Stradiņa monogrāfija „Zinātnes un augstskolu sākotne Latvijā”Astronomija filatēlijāSaules neitrīnoRainis Zvaigžņotā Debess un DainasNASA’s zonde Deep Impact un komēta Hartley 2Fricis GulbisAsteroīda P/2010 A2 astePilns Saules aptumsums - 2010.g. 11.jūlijs Francijas PolinēzijaGrāmata „Einšteins. Viņa dzīve un Visums”Astronomiskās parādības - 2010Astronomiskās parādības - 2011Par Nibiru un Pasaules galuLU fizikas docents Ojārs Šmits (1930-1993)Koncerts Astrophonia ValmierāLatvijas Astronomijas biedrības observatorija SiguldāPar misēkļiem Astronomiskajā kalendārā 2011V.Struves ģeodēziskais loks - pastmarkasValdemāram Murevskim – 100Zvaigznes Gleznotāja β planētaMstislavam Keldišam – 100Jaunākie ieguvumi “Zvaigžņotās Debess” bibliotēkāDaļējs Saules aptumsums 2011.gada 4.janvārīMarsa ekspedīciju kuģu Orion un Dragon maketiSkaitļu pieraksti senajās kultūrās
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Fast atom bombardment and field desorption mass spectrometry: Comparative aspects of analytical development and bioanalytical application

1983

BioanalysisChemistryClinical BiochemistryAnalytical chemistryGeneral Materials ScienceGeneral MedicineFast atom bombardmentField desorption mass spectrometryMass spectrometryAnalytical ChemistryFresenius' Zeitschrift für analytische Chemie
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Homenaje a Madrid ¡Madrid, asesinados sus hijos, arrasados sus monumentos, en llamas sus tesoros de arte! ... : Del discurso pronunciado en Valencia …

En la part superior esquerra el mapa de la Península Ibèrica. Sobre la seva meitat oriental el marc d'un escut en blanc sobre el qual està escrit part del discurs del President Azaña. Baix, els lleons de l'estàtua de la Cibeles de Madrid

Bombardeigs Madrid 1936-1939 Cartells
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Al cobijo de la noche y traidoramente los barcos fascistas que piratean en el Mediterráneo lanzaron sus proyectiles mortíferos sobre Valencia, la ciu…

Existeix altre cartell amb la mateixa llegenda però amb fotos diferents Fotografies de grups de persones, habitatges bombardejats i l'Hospital de Sang, amb comentaris explicatius al peu de cada foto

Bombardeigs València 1936-1939 Cartells
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Las ruinas del Arte de España Son una acusación más contra el fascismo.

La composició divideix en quatre parts el cartell, la llegenda es troba en el quadrant superior esquerre i inferior dret; en les altres dues seccions, es veuen fotografies d'una façana modernista i d'un temple parcialment destruït

Bombardeigs aeris Espanya 1936-1939 Cartells
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