Search results for "BC"
showing 10 items of 1938 documents
Periscope endograft technique to revascularize the left subclavian artery during thoracic endovascular aortic repair.
2013
Purpose: To present early and midterm results of the periscope endograft (PG) technique to maintain left subclavian artery (LSA) blood flow in thoracic endovascular aortic repairs (TEVAR) involving zone 3. Methods: From April 2010 to January 2013, 14 consecutive high-risk patients (11 men; mean age 7068 years, range 56–87) underwent TEVAR with the PG technique for 10 thoracic aortic aneurysms (TAA), 2 traumatic aortic ruptures, and 2 aortic dissections without a suitable landing zone (.2 cm distal to the LSA). Five procedures were performed emergently for rupture (3 TAAs and the 2 trauma cases). Two patients had a periscope deployed in an aberrant right subclavian artery. The periscope endo…
Calcium mediated polyelectrolyte adsorption on like-charged surfaces.
2011
International audience; Monte Carlo simulations within the primitive model of calcium-mediated adsorption of linear and comb polyelectrolytes onto like-charged surfaces are described, focusing on the effect of calcium and polyion concentrations as well as on the ion pairing between polymers and calcium ions. We use a combination of Monte Carlo simulations and experimental data from titration and calcium binding to quantify the ion pairing. The polymer adsorption is shown to occur as a result of surface overcharging by Ca2+ and ion pairing between charged monomers and Ca2+. In agreement with experimental observations, the simulations predict that the polymer adsorption isotherm goes through …
Siracusa e la Sicilia nel III secolo a.C.: problemi conoscitivi e proposte di lettura dei fenomeni urbanistici e architettonici
2017
L’evoluzione sotto il profilo urbanistico e architettonico delle città di Sicilia nel III secolo a.C. può essere compresa solo a partire da un esame delle evidenze di Siracusa, la maggiore città dell’Occidente greco-ellenistico e capitale di un regno che sotto Agatocle e soprattutto sotto Ierone II vede un prodigioso sviluppo non solo per l’estensione dell’area urbana, ma soprattutto per la riconfigurazione dello spazio cittadino in forme innovative, destinate a influenzare in maniera decisiva anche le città minori del regno e dell’Oriente dell’isola, e successivamente anche dei comprensori centro-occidentali e settentrionali. L’aspetto più importante e programmatico nella rimodulazione del…
Randomized Trial : D-Glyceric Acid Activates Mitochondrial Metabolism in 50–60-Year-Old Healthy Humans
2021
Background: Based on earlier studies, natural metabolite D-glyceric acid (DGA) does not seem to play any role in whole-body metabolism. Nevertheless, one ethanol oxidation-related rat study with controversial results raised our interest. According to preparatory studies for the regulatory approval of DGA, some highly conserved mechanism seems to subtly activate the cellular energy metabolism. Therefore, the present 25-days double-blind human study with placebo control was initiated. Purpose: The main target in the present study with 27 healthy 50–60-year-old human volunteers was to find out whether an “acute” 4-days and a longer 21-days exogenous DGA regimen caused moderate activation of th…
Heme Oxygenase-1 and Blood Bilirubin Are Gradually Activated by Oral D-Glyceric Acid
2022
It has been shown that small doses of oral D-glyceric acid (DGA) activate mitochondrial metabolism and reduce inflammation among 50–60-year-old healthy volunteers. The present results with the same small doses reveal that after a 4-day DGA regimen, a dose of DGA activated the HO-1 pathway acutely, while enhanced inflammatory status after the 4-day DGA regimen seemed to be able to downregulate the HO-1 pathway in non-acute measurement. Blood bilirubin was strongly upregulated towards the end of the altogether 21-day study period with positive associations towards improved inflammation and reduced blood triglycerides. After the 4-day DGA regimen, hepatic inflow of blood bilirubin with albumin…
Real-world experience with obeticholic acid in patients with primary biliary cholangitis
2021
Background & aims Obeticholic acid (OCA) is the second-line treatment approved for patients with primary biliary cholangitis (PBC) and an inadequate response or intolerance to ursodeoxycholic acid. We aimed to evaluate the effectiveness and safety of OCA under real-world conditions. Methods Patients were recruited into the Italian PBC Registry, a multicentre, observational cohort study that monitors patients with PBC at national level. The primary endpoint was the biochemical response according to Poise criteria; the secondary endpoint was the biochemical response according to normal range criteria, defined as normal levels of bilirubin, alkaline phosphatase (ALP), and alanine aminotransfer…
Toward a Dimensional Assessment of Externalizing Disorders in Children : Reliability and Validity of a Semi-Structured Parent Interview
2020
Objective: This study assesses the reliability and validity of the DSM-5-based, semi-structured Clinical Parent Interview for Externalizing Disorders in Children and Adolescents (ILF-EXTERNAL). Method: Participant data were drawn from the ongoing ESCAschool intervention study. The ILF-EXTERNAL was evaluated in a clinical sample of 474 children and adolescents (aged 6−12 years, 92 females) with symptoms of attention-deficit/hyperactivity disorder (ADHD). To obtain interrater reliability, the one-way random-effects, absolute agreement models of the intraclass correlation (ICC) for single ICC(1,1) and average measurements ICC(1,3) were computed between the interviewers and two independent rate…
Montmorilonīta-antociānu organokompleksi: fizikāli ķīmiskās īpašības un izmantošanas risinājumi
2020
Bakalaura darba ietvaros tika pētīta antociānu interkalācija montmorilonīta struktūrā un veikta iegūtā organokompleksa fizikāli ķīmisko īpašību izpēte inovatīvu un videi draudzīgu materiālu izstrādē. Pētījuma ietvaros izvēlēts rūpnieciski ražots māla minerāls- montmorilonīts, kas tika modificēts ar antociāniem no melnaugļu aroniju ogu (Aronia melanocarpa L.) vai vīnogu (Vitis vinifera) izspiednēm. Antociānu sorbcija uz māla minerāla tika pētīta atkarībā no sorbenta iesvara, sorbāta koncentrācijas, vides pH un temperatūras. Iegūto kompozītmateriālu īpašības tika raksturotas ar Furjē transformācijas infrasarkanās gaismas spektroskopijas (FTIS) un termogravimetrijas analīzes (TGA) metodēm. Ieg…
Videi draudzīgu sapropeļa skaņas absorbcijas kompozītmateriālu izveide un to mikrobioloģiskā noturība
2021
Bakalaura darba “Videi draudzīgu sapropeļa skaņas absorbcijas kompozītmateriālu izveide un to mikrobioloģiskā noturība” ietvaros kopumā tika izveidoti 100 videi draudzīgu kompozītmateriālu paraugi, kā materiālu saistvielu, izmantojot organiskus ezera nogulumus (sapropeli), kā pildvielas izmantojot sfagnu sūnas, lina šķiedru un vermikulītu. Materiāliem arī tika pievienotis biocīds un tā dabīgais aizvietotājs – SIA ALINA produkts “ALINA LIFETM” organomāli. Darba teorētiskajā daļā tika apkopota zinātniskā literatūra par videi draudzīgiem kompozītmateriāliem un videi draudzīgas būvniecības piemēriem, materiālu mikrobioloģisko rezistenci, iekštelpu mikrobioloģisko piesārņojumu un vides piesārņoj…
Virsrakstu un apakšvirsrakstu tekstveides īpatnības žurnālā "BBC History Magazine"
2020
Retorika palīdz pārliecināt, iespaidot un ietekmēt auditoriju. To plaši izmanto žurnālistikas jomā, jo tai ir līdzīgi mērķi. Virsraksts ir efektīvs līdzeklis, lai pārliecinātu un stimulētu interesi, jo tas ir pirmais, kam lasītājs pievērš uzmanību. Šajā pētījumā tika analizētas BBC History Magazine virsrakstu retoriskās iezīmes, lai izpētītu virsrakstu pārliecinošo ietekmi. Pētījuma metode bija diskursa analīze. Retoriskās iezīmes tika analizētas sintakses, laika, retorisko līdzekļu izmantošanas un grafiskā attēlojuma ziņā. Atklājās, ka nominatīvais teikums ir visizplatītākā struktūra virsrakstā, pagātne bija visbiežāk satopamā darbības vārda laika forma, metafora un aliterācija bija visizp…