Search results for "BD"

showing 10 items of 3363 documents

Hereditary angioedema with normal C1-inhibitor activity in women.

2000

Summary Background Hereditary angioedema (HAE) is a well defined autosomal dominant disease (Mendelian Inheritance in Man #106100) that results from an inherited deficiency of C1 (the activated first component of complement) inhibitor function. We report an unusual variant of HAE with normal biochemical C1-inhibitor function, occurring only in women. Methods We screened 574 patients with recurrent angioedema of the skin for presence of HAE. 283 patients were selected, in whom angioedema was associated with abdominal pain attacks or recurrent life-threatening episodes of upper-airway obstruction, or both, rather than with urticaria. We measured C1-inhibitor concentration and functional activ…

AdultMaleX ChromosomeAdolescentGenetic LinkageComplement C1 Inactivator ProteinsC1-inhibitorEcallantideSex FactorsRecurrenceTerminology as TopicmedicineHumansHereditary Angioedema Type IIISex RatioFamily historyAngioedemaChildDominance (genetics)Genes DominantAngioedemabiologybusiness.industryAutosomal dominant traitComplement C4General MedicineMiddle Agedmedicine.diseaseAbdominal PainPedigreeAirway ObstructionImmunologyHereditary angioedemaMutationbiology.proteinFemalemedicine.symptombusinessmedicine.drugLancet (London, England)
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Safety and feasibility of a neuromuscular electrical stimulation chronaxie-based protocol in critical ill patients: A prospective observational study

2017

International audience; Purpose: The aim of this study was to evaluate the safety and feasibility of a neuromuscular electrical stimulation (NMES) protocol based on neuromuscular excitability and applied in numerous muscle groups of critical ill patients.Materials and methods: We performed a prospective observational study using an NMES applied daily and bilaterally into 5 muscle groups in lower limbs for 3 consecutive days. The characteristics of NMES were 90 contractions per muscle, pulse width equal to chronaxie, and a pulse frequency of 100 Hz. We assessed safety with central venous oxygen saturation, serum lactate, and creatine phosphokinase measurements. To evaluate feasibility, we re…

AdultMalecontractionsmedicine.medical_specialtyChronaxieCritical CareElectric Stimulation TherapyStimulation030204 cardiovascular system & hematologyCritical Care and Intensive Care Medicineknee extensor muscles03 medical and health sciences0302 clinical medicine[ SDV.MHEP ] Life Sciences [q-bio]/Human health and pathologymedicinePulse frequencyHumanscritical illnessskeletal-muscleLactic AcidProspective StudiesvoluntaryMuscle SkeletalAPACHEIntensive care unit-acquired weaknessbiologyacquired weaknessbusiness.industryRehabilitationMuscle weakness030208 emergency & critical care medicinethicknessNeuromuscular stimulationMale patientIntensive careAnesthesiarhabdomyolysisPhysical therapybiology.proteinFemaleObservational studyCreatine kinaseelectromyostimulationSerum lactateSafetystrengthbusinessChronaxyMuscle ContractionJournal of Critical Care
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Clinical course of patients with episodic cluster headache treated with corticosteroids inproximity to the sphenopalatine ganglion: A preliminary stu…

2011

Objective: A study is made of the clinical course of patients with episodic cluster headache following the injection of corticosteroids in the proximity of the sphenopalatine ganglion of the affected side. Study Design: A retrospective observation study was made corresponding to the period between 2006 and 2010. Patients with episodic cluster headache received corticosteroid infiltrations in the vicinity of the sphenopalatine ganglion. Data were collected to assess the clinical course, quantifying pain intensity and quality of life. A total of 23 patients (11 women and 12 men) with a mean age of 50.4 years (range 25-65) were included. Forty percent of the patients had undergone dental extra…

AdultMalemedicine.drug_classPterygopalatine FossaCluster HeadacheQuadrant (abdomen)Quality of lifeEpisodic cluster headacheAdrenal Cortex HormonesmedicineHumansGeneral DentistryAgedRetrospective StudiesUnbearable Painbusiness.industryClinical courseGanglia ParasympatheticMean ageMiddle Aged:CIENCIAS MÉDICAS [UNESCO]GanglionOrofacial Pain-TMJDTreatment Outcomemedicine.anatomical_structureOtorhinolaryngologyAnesthesiaUNESCO::CIENCIAS MÉDICASCorticosteroidFemaleResearch-ArticleSurgerybusinessMedicina Oral Patología Oral y Cirugia Bucal
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Focal nodular hyperplasia-like lesions in patients with cavernous transformation of the portal vein: prevalence, MR findings and natural history.

2011

PURPOSE: To retrospectively investigate the prevalence, MR findings, natural history, and association with other hepatic lesions of focal nodular hyperplasia (FNH)-like lesions in a cohort of consecutive patients with cavernous transformation of the portal vein (CTPV). MATERIALS AND METHODS: This retrospective IRB-approved study comprised 58 patients (32 men, 26 women; average age, 50 years) with CTPV who underwent liver MR imaging between 2000 and 2008. MR images were assessed by two radiologists in consensus for the presence of (a) FNH-like lesions and other liver lesions, and (b) other imaging findings. Patients were assigned to a stable or progressive clinical course based on lesion cha…

AdultMalemedicine.medical_specialtyAbdomen Liver Cavernous transformation of the portal vein Benign liver neoplasms Magnetic resonance imagingAdenomaLesionHemangiomaCohort StudiesReference ValuesmedicineImage Processing Computer-AssistedHumansRadiology Nuclear Medicine and imagingLiver focal nodular hyperplasia cavernomatosis portal veinNeuroradiologyAgedRetrospective Studiesmedicine.diagnostic_testbusiness.industryPortal VeinLiver NeoplasmsFocal nodular hyperplasiaMagnetic resonance imagingInterventional radiologyGeneral MedicineMiddle Agedmedicine.diseaseMagnetic Resonance Imagingmedicine.anatomical_structureTreatment OutcomeFocal Nodular HyperplasiaAbdomenFemaleRadiologymedicine.symptombusinessSettore MED/36 - Diagnostica Per Immagini E RadioterapiaEuropean radiology
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Is laparoscopic approach still a risk factor for postappendectomy intra-abdominal abscess?

2020

Background The impact of laparoscopic appendectomy (LA) on the incidence of intra-abdominal abscess (IAA) remains controversial. We aimed to identify risk factors for postappendectomy IAA and assess the impact of appendectomy approach in postoperative morbidity. Methods A retrospective single-center study including consecutive patients who underwent appendectomy for acute appendicitis between 2015 and 2018 was performed. Demographic, clinical, intraoperative, and perioperative variables were collected. Univariate and multivariate analyses was performed to detect independent risk factors for IAA. Comparison of LA and open appendectomy was conducted, and propensity score model (PSM) was used …

AdultMalemedicine.medical_specialtyAbdominal AbscessCritical Care and Intensive Care MedicineYoung Adult03 medical and health sciences0302 clinical medicineRisk FactorsAppendectomyHumansMedicineRisk factorAbscessRetrospective StudiesPostoperative Carebusiness.industryIncidence (epidemiology)030208 emergency & critical care medicineRetrospective cohort studyPerioperativeMiddle AgedAppendicitismedicine.diseaseAppendicitisSurgeryLogistic ModelsPropensity score matchingCohortFemaleLaparoscopySurgerybusinessJournal of Trauma and Acute Care Surgery
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Bilateral ureteral obstruction and renal failure caused by massive retroperitoneal hematoma: is there a pelvic compartment syndrome analogous to abdo…

1998

Objectives: To describe an intrapelvic compartment syndrome analogous to abdominal compartment syndrome and to characterize its diagnosis and treatment. Design: Retrospective analysis. Setting: Level I trauma center. Patients: Three patients with pelvic ring or acetabular fractures presented with bilateral ureteral obstruction, renal organ failure. and anuria due to direct compression of both ureters in the true pelvis by a massive retroperitoneal hematoma, Intervention: Surgical therapy consisted of fracture stabilization, decompression of the retroperitoneal space, and evacuation of the hematoma. Persistent isolated bleeding points were either embolized preoperatively or ligated. Results:…

AdultMalemedicine.medical_specialtyAbdominal compartment syndromeDecompressionUrologyurologic and male genital diseasesCompartment SyndromesRetroperitoneal hematomaFractures BoneUreterHematomaMedicineRetroperitoneal spaceHumansOrthopedics and Sports MedicinePelvic compartmentRetroperitoneal SpaceCompartment (pharmacokinetics)Pelvic BonesHematomabusiness.industryAcetabulumGeneral MedicineAcute Kidney InjuryMiddle Agedmedicine.diseaseSurgeryRadiographysurgical procedures operativemedicine.anatomical_structureSurgeryAnuriaFemaleRadiologymedicine.symptombusinessKidney diseaseUreteral ObstructionJournal of orthopaedic trauma
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Hereditary Angioedema: New Findings Concerning Symptoms, Affected Organs, and Course

2005

Abstract Purpose Hereditary angioedema (HAE) due to C1 inhibitor deficiency is clinically characterized by relapsing skin swellings, abdominal pain attacks, and life-threatening upper airway obstruction. Our aim was to examine a temporal and spatial pattern of the edema episodes by evaluating the long-term course of hereditary angioedema in order to establish a specific swelling pattern. Subjects and methods Data were generated from 221 patients with C1 inhibitor deficiency by asking them about symptoms they experienced during their edema episodes. Documentation was accomplished through the use of standardized questionnaires. Results A total of 131110 edema episodes were observed. Clinical …

AdultMalemedicine.medical_specialtyAbdominal painAdolescentLate onsetComplement C1 Inactivator ProteinsLaryngeal EdemaSeverity of Illness IndexDisease-Free SurvivalEcallantideEdemamedicineHumansAngioedemaChildSerpinsRetrospective StudiesAngioedemabusiness.industryGeneral MedicineMiddle AgedAirway obstructionmedicine.diseaseDermatologySurgeryHereditary angioedemaFemalemedicine.symptombusinessComplement C1 Inhibitor Proteinmedicine.drugThe American Journal of Medicine
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Bowel wall thickening: inquire or not inquire? Our guidelines

2018

Introduction Bowel wall thickening is not an uncommon finding among patient undergoing abdomen CT scan. It may be caused by neoplastic, inflammatory, infectious or ischaemic conditions but also be a normal variant. Although specific radiologic patterns may direct to a precise diagnosis, occasionally misidentification may occur. Thus, in the absence of guidelines, further and not always needed diagnostic procedures (colonoscopy, esophagogastroduodenoscopy or capsule endoscopy) are performed. Patients and methods We conducted a retrospective study on data collected from May 2016 to June 2017. We selected 40 adult patients, admitted in Emergency Department with "abdominal pain" and undergone a…

AdultMalemedicine.medical_specialtyAbdominal painColorectal cancerColonoscopyEndoscopy Gastrointestinallaw.inventionDiverticulitis Colonicbowel wall - CT scan03 medical and health sciencesYoung Adult0302 clinical medicineCapsule endoscopylawIschemiamedicineHumansAgedGastrointestinal NeoplasmsRetrospective StudiesAged 80 and overmedicine.diagnostic_testbusiness.industryEsophagogastroduodenoscopyStomachCancerMuscle SmoothDiverticulitisMiddle Agedmedicine.diseaseColitisEnteritisEndoscopyAbdominal PainIntestinesSettore MED/18 - Chirurgia Generale030220 oncology & carcinogenesisGastritis030211 gastroenterology & hepatologyFemaleOriginal ArticleRadiologymedicine.symptomEmergenciesbusinessTomography X-Ray Computed
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Confirmatory factor analysis of the Patient Assessment of Constipation-Symptoms (PAC-SYM) among patients with chronic constipation.

2015

Background and aim: PAC-SYM is widely adopted to asses constipation severity. However, it has been validated in a small sample, few items have been included based on expert opinion and not on empirical grounds, and its factor structure has never been replicated. We aimed at evaluating the psychometric properties of PAC-SYM in patients with chronic constipation. Methods: We enrolled 2,203 outpatients with chronic constipation in two waves. We used wave I sample to test the psychometric properties of the PAC-SYM and wave II sample to cross-validate its factor structure, to assess criterion validity, responsiveness to clinical change, and its minimal clinically important difference. Results: O…

AdultMalemedicine.medical_specialtyAbdominal painConstipationConstipation severityChronic constipation; Chronic non-organic constipation; Constipation severity; Quality of life; Adult; Chronic Disease; Constipation; Female; Humans; Male; Middle Aged; Patient Care; Quality of Life; Reproducibility of Results; Surveys and Questionnaires; Factor Analysis Statistical; Public Health Environmental and Occupational Health; Medicine (all)Reproducibility of ResultChronic constipation; Chronic non-organic constipation; Constipation severity; Quality of life; Adult; Chronic Disease; Constipation; Female; Humans; Male; Middle Aged; Patient Care; Quality of Life; Reproducibility of Results; Surveys and Questionnaires; Factor Analysis Statistical; Public Health Environmental and Occupational HealthQuality of lifeInternal medicineSurveys and QuestionnairesmedicineCriterion validitySurveys and QuestionnaireHumansChronic constipationSettore MED/12 - Gastroenterologiabusiness.industryChronic constipationMinimal clinically important differenceMedicine (all)Environmental and Occupational HealthSettore MED/09 - MEDICINA INTERNAPublic Health Environmental and Occupational HealthReproducibility of ResultsStatisticalMiddle Agedmedicine.diseaseConfirmatory factor analysisSettore MED/18 - Chirurgia GeneraleChronic DiseasePhysical therapyQuality of LifeFunctional constipationChronic constipation; Chronic non-organic constipation; Constipation severity; Quality of life; Public Health Environmental and Occupational HealthChronic constipation; Chronic non-organic constipation; Constipation severity; Quality of life; Adult; Chronic Disease; Constipation; Female; Humans; Male; Middle Aged; Patient Care; Quality of Life; Reproducibility of Results; Surveys and Questionnaires; Factor Analysis StatisticalFemalePublic HealthChronic non-organic constipationPatient Caremedicine.symptombusinessFactor Analysis StatisticalFactor AnalysisConstipationHumanQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation
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An outbreak of food poisoning due to a genogroup I norovirus.

2005

Norovirus infection is associated with approximately 90% of epidemic non-bacterial acute gastroenteritis. The objective of this study is to describe an outbreak of norovirus genogroup I gastroenteritis which affected workers in a hospital and was attributed to food prepared by an infected food handler. Forty cases were detected, of whom 80% were interviewed. The index case was the cook employed in the hospital cafeteria. The following symptoms were observed: abdominal pain in 90·6%, vomiting in 71·9%, diarrhoea in 71·9%, general indisposition in 62·5%, headaches in 53·1% and fever in 32·4% of cases. The initial symptoms were abdominal pain in 37% and vomiting in 28%. Of the 14 samples analy…

AdultMalemedicine.medical_specialtyAbdominal painGenotypeEpidemiologyFood HandlingCafeteriaFood Contaminationmedicine.disease_causeDisease OutbreaksFoodborne Diseasesfluids and secretionsInternal medicinemedicineHumansIndex caseCaliciviridae InfectionsFood poisoningbiologybusiness.industryNorovirusOutbreakmedicine.diseasebiology.organism_classificationVirologyGastroenteritisInfectious DiseasesSpainVomitingNorovirusFemaleHeadachesmedicine.symptombusinessResearch ArticleEpidemiology and infection
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