Search results for "BDI"
showing 10 items of 208 documents
Calcul direct d'une tesselation de la surface limite pour les schémas de subdivision uniformes
2017
International audience; Le peu d'utilisation des surfaces de subdivision dans les systèmes CAO est principalement lié au fait que la surface est le plus souvent seulement approchée par des niveaux de raffinement successifs, ce qui induit un manque de pré-cision. De plus, il est difficile d'intégrer la représentation des surfaces de subdivision dans le noyau géométrique (ensemble de primitives et d'outils) des applications CAO. C'est dans ce but que nous décrirons un formalisme général de construction de surfaces de subdivision basé sur les Systèmes Itérés de Fonctions. Le principal apport est que toutes les surfaces de subdivision classiques sont gérées de la même manière quel que soit le s…
Sponge proteins are more similar to those of Homo sapiens than to Caenorhabditis elegans
2000
We compared 42 phylogenetically conserved proteins from four marine sponges [Porifera] with almost the complete set of Caenorhabditis elegans proteins and all known proteins from humans. The majority of the sponge proteins are significantly more similar to human than to C. elegans orthologues/homologues. This finding reflects the accelerated evolutionary rate in the C. elegans lineage, since sponges split off first from the common ancestor of all multicellular animals. Furthermore, three sponge/human proteins were not found in C. elegans: (2–5)A synthetase, DNA repair helicase and lens βγ -crystallin. Sponges are the source of the most ancient proteins already present in the common ancestor…
Conceptualization for intended action: A dynamic model
2023
Concepts are the building blocks of higher-order cognition and consciousness. Building on Conceptual Spaces Theory (CST) and proceeding from the assumption that concepts are inherently dynamic, this paper provides historical context to and significantly elaborates the previously offered Iterative Subdivision Model (ISDM) with the goal of pushing it toward empirical testability. The paper describes how agents in continuous interaction with their environment adopt an intentional orientation, estimate the utility of the concept(s) applicable to action in the current context, engage in practical action, and adopt any new concepts that emerge: a largely pre-intellectual cycle that repeats essent…
Toxicological assessment of mesoporous silica particles in the nematode Caenorhabditis elegans
2018
[EN] Here we report the toxicological evaluation of mesoporous silica particles (MSPs) in the nematode C. elegans. Specifically, we have investigated the effect of bare micro- (M0) and nano-sized (N0) MSPs, and their corresponding functionalized particles with a starch derivative (Glu-N) (M1 and N1, respectively) on C. elegans ageing parameters. The toxicity of MSPs, their impact on C. elegans lifespan, movement capacity, progeny and ability to survive upon exposure to acute oxidative stress were assessed. This study demonstrated that both size particles assayed (M0 and N0), labeled with rhodamine and monitored through fluorescence microscopy, are ingested by the nematode. Moreover, toxicit…
Synaptic tetraspan vesicle membrane proteins are conserved but not needed for synaptogenesis and neuronal function in Caenorhabditis elegans
2006
Tetraspan vesicle membrane proteins (TVPs) comprise a major portion of synaptic vesicle proteins, yet their contribution to the synaptic vesicle cycle is poorly understood. TVPs are grouped in three mammalian gene families: physins, gyrins, and secretory carrier-associated membrane proteins (SCAMPs). In Caenorhabditis elegans , only a single member of each of these families exists. These three nematode TVPs colocalize to the same vesicular compartment when expressed in mammalian cells, suggesting that they could serve overlapping functions. To examine their function, C. elegans null mutants were isolated for each gene, and a triple mutant was generated. Surprisingly, these animals develop …
From Layered Molybdic Acid to Lower-Dimensional Nanostructures by Intercalation of Amines under Ambient Conditions
2006
Nanostructures of varied dimensionality such as rods, scrolls, and disks of molybdenum oxide have been synthesized in gram quantities under ambient conditions using exfoliation of the layers as a synthetic tool. Intercalation of alkylamines (CnH2n+2NH2, where n = 3, 4, 8, 12, and 16) into yellow molybdic acid (MoO3·2H2O) and subsequent treatment with nitric acid resulted in molybdenum oxide nanorods, nanodisks, or oxide−amine composite nanorods. The sizes of the nanoparticles range from a few nanometers to micrometers in length and 10 to 200 nm in diameter. Detailed X-ray, scanning electron microscopy, and transmission electron microscopy analyses reveal an inverse relation between the size…
Insect Immune Evasion by Dauer and Nondauer Entomopathogenic Nematodes
2021
The immune response of animals, including insects, is overcome by some parasites. For example, dauer larvae (DL) of the obligate entomopathogenic nematodes (EPNs) Heterorhabditis and Steinernema can invade insects, evade their defenses, and cause death. Although DL were long assumed to be the only infective stage of nematodes, recent reports suggest that L2-L3 larvae of facultative EPNs are also capable of killing insects. There are no studies, to our knowledge, about the role of nonimmunological barriers (the exoskeleton and its openings) in avoiding infection by DL and L2-L3 larvae, or whether these larval stages evade the host immune system in the same way. The objective of this study wa…
Protease-mediated processing of Argonaute proteins controls small RNA association
2020
SummarySmall RNA pathways defend the germlines of animals against selfish genetic elements and help to maintain genomic integrity. At the same time, their activity needs to be well-controlled to prevent silencing of ‘self’ genes. Here, we reveal a proteolytic mechanism that controls endogenous small interfering (22G) RNA activity in the Caenorhabditis elegans germline to protect genome integrity and maintain fertility. We find that WAGO-1 and WAGO-3 Argonaute (Ago) proteins are matured through proteolytic processing of their unusually proline-rich N-termini. In the absence of DPF-3, a P-granule-localized N-terminal dipeptidase orthologous to mammalian DPP8/9, processing fails, causing a cha…
Herramientas matemáticas multi-escala para el tratamiento de señales
2019
En aquesta tesi doctoral, presentada com a compendi d'articles, es desenvolupen diverses eines matemàtiques per a processar senyals procedents de problemes reals. Aquestes tècniques estan basades en la teoria de la multi-resolució de Harten i la teoria d'esquemes de subdivisió. En aquest compendi es recullen treballs de disseny de nous esquemes de subdivisió no-lineals i aplicacions en Química Analítica, en optimització i en el disseny de velers de competició, entre d'altres. In this doctoral thesis, presented as a compendium of articles, various mathematical tools are developed to process signals from real problems. These techniques are based on Harten's multi-resolution framework and subd…
Carlo Verardi, Historia Baetica. Edizione critica e commento.
2014
La Historia Baética es un drama histórico en latín compuesto en Roma durante el invierno de 1492 por el secretario apostólico Carlo Verardi . Este estudio tiene como objetivo restituir el texto de la Historia Baetica con una edición filológicamente correcta, acompañada de una investigación crítico-literaria sobre la obra y de un estudio histórico sobre el contexto político y cultural que dio lugar a su génesis. La obra está inspirada en los acontecimientos que rodearon la rendición del último reducto árabe en España, el Sultanato de la dinastía nazarí de Granada, reconquistado por el ejército católico de Fernando II de Aragón el 2 de enero de 1492, después de diez años de asedio. El evento,…