Search results for "BEP"
showing 10 items of 119 documents
Appetizer or main dish? Explaining the use of Facebook news posts as a substitute for other news sources
2019
An increasing number of, especially younger, users use Facebook as their primary source for news about political and societal issues. At the same time, research suggests that Facebook use contributes to societal knowledge gaps. Against this background, we investigate the antecedents of using Facebook as a substitute for other news sources. We argue that exposure to news posts on Facebook increases the feeling of being well-informed, regardless of actual knowledge acquisition. This might lead users, especially those with a low need for cognition (NfC), to use Facebook as a substitute for other news sources. We test these assumptions with an online survey (n=390) of German Internet users. Res…
Paracrine regulation of neural stem cells in the subependymal zone.
2012
Stem cells maintain their self-renewal and multipotency capacities through a self-organizing network of transcription factors and intracellular pathways activated by extracellular signaling from the microenvironment or "niche" in which they reside in vivo. In the adult mammalian brain new neurons continue to be generated throughout life of the organisms and this lifelong process of neurogenesis is supported by a reservoir of neural stem cells in the germinal regions. The discovery of adult neurogenesis in the mammalian brain has sparked great interest in defining the conditions that guide neural stem cell (NSC) maintenance and differentiation into the great variety of neuronal and glial sub…
Adult Neural Stem Cells Are Alerted by Systemic Inflammation through TNF-α Receptor Signaling.
2021
Summary Adult stem cells (SCs) transit between the cell cycle and a poorly defined quiescent state. Single neural SCs (NSCs) with quiescent, primed-for-activation, and activated cell transcriptomes have been obtained from the subependymal zone (SEZ), but the functional regulation of these states under homeostasis is not understood. Here, we develop a multilevel strategy to analyze these NSC states with the aim to uncover signals that regulate their level of quiescence/activation. We show that transitions between states occur in vivo and that activated and primed, but not quiescent, states can be captured and studied in culture. We also show that peripherally induced inflammation promotes a …
Architecture and cell types of the adult subventricular zone: in search of the stem cells.
1998
Neural stem cells are maintained in the subventricular zone (SVZ) of the adult mammalian brain. Here, we review the cellular organization of this germinal layer and propose lineage relationships of the three main cell types found in this area. The majority of cells in the adult SVZ are migrating neuroblasts (type A cells) that continue to proliferate. These cells form an extensive network of tangentially oriented pathways throughout the lateral wall of the lateral ventricle. Type A cells move long distances through this network at high speeds by means of chain migration. Cells in the SVZ network enter the rostral migratory stream (RMS) and migrate anteriorly into the olfactory bulb, where t…
Neurogenesis in adult subventricular zone
2002
Much excitement has been generated by the identification of adult brain regions harboring neural stem cells and their continual generation of new neurons throughout life. This is an important departure from traditional views of the germinal potential of the postnatal brain. However, a more profound
Endothelial NT-3 Delivered by Vasculature and CSF Promotes Quiescence of Subependymal Neural Stem Cells through Nitric Oxide Induction
2014
SummaryInteractions of adult neural stem cells (NSCs) with supportive vasculature appear critical for their maintenance and function, although the molecular details are still under investigation. Neurotrophin (NT)-3 belongs to the NT family of trophic factors, best known for their effects in promoting neuronal survival. Here we show that NT-3 produced and secreted by endothelial cells of brain and choroid plexus capillaries is required for the quiescence and long-term maintenance of NSCs in the mouse subependymal niche. Uptake of NT-3 from irrigating vasculature and cerebrospinal fluid (CSF) induces the rapid phosphorylation of endothelial nitric oxide (NO) synthase present in the NSCs, lea…
Measurement of the absolute branching fraction for Λc+→Λμ+νμ
2017
Abstract We report the first measurement of the absolute branching fraction for Λ c + → Λ μ + ν μ . This measurement is based on a sample of e + e − annihilation data produced at a center-of-mass energy s = 4.6 GeV , collected with the BESIII detector at the BEPCII storage rings. The sample corresponds to an integrated luminosity of 567 pb − 1 . The branching fraction is determined to be B ( Λ c + → Λ μ + ν μ ) = ( 3.49 ± 0.46 ( stat ) ± 0.27 ( syst ) ) % . In addition, we calculate the ratio B ( Λ c + → Λ μ + ν μ ) / B ( Λ c + → Λ e + ν e ) to be 0.96 ± 0.16 ( stat ) ± 0.04 ( syst ) .
Measurement of cross sections of the interactions e+e−→ ϕϕω and e+e−→ ϕϕϕ at center-of-mass energies from 4.008 to 4.600 GeV
2017
Abstract Using data samples collected with the BESIII detector at the BEPCII collider at six center-of-mass energies between 4.008 and 4.600 GeV, we observe the processes e + e − → ϕ ϕ ω and e + e − → ϕ ϕ ϕ . The Born cross sections are measured and the ratio of the cross sections σ ( e + e − → ϕ ϕ ω ) / σ ( e + e − → ϕ ϕ ϕ ) is estimated to be 1.75 ± 0.22 ± 0.19 averaged over six energy points, where the first uncertainty is statistical and the second is systematic. The results represent first measurements of these interactions.
Dark photon search in the mass range between 1.5 and 3.4 GeV/c2
2017
Physics letters / B 774, 252 - 257 (2017). doi:10.1016/j.physletb.2017.09.067
Measurement of e+ e- → DD cross sections at the ψ(3770) resonance
2018
Chinese physics / C High energy physics and nuclear physics C 42(8), 083001 (2018). doi:10.1088/1674-1137/42/8/083001