Search results for "BES"

L’écrivain à l’œuvre ou la valeur travail dans les romans de Rafael Chirbes

2017

International audience

Theoretical study of the interaction between carbon nanotubes and carboplatin anticancer molecules

2015

International audience; Full DFT calculations were carried out to study the interactions between single-wall functionalized carbon-based metallic nanotubes (CNTs) and carboplatin anticancer drugs. The geometry of the CNT-carboplatin was optimized considering different molecular configurations on inner and outer surfaces of the nanotubes. Simulation results show that the most stable physisorption state for molecules is to be located inside the nanotubes in a parallel configuration. Furthermore{,} we demonstrated that the molecular physisorption was reinforced as soon as the number of encapsulated carboplatin molecules increased{,} leading to a favored state where the nanovector is filled by …

Theoretical Simulations on Electric Properties of CNT-Me and GNR-Me Interconnects Using Effective Media Approach

2011

Abstract To overcome disadvantages of nowadays microtechnology, a further miniaturization of electronic devices, high integration level as well as increase of both operation frequencies and power density is required, including the use of adequate materials and innovative chip interconnects. Due to their unique physical properties, especially due to a ballistic (without losses) mechanism of conductivity, carbon nanotubes (CNTs) and graphene nanoribbons (GNRs) attract a permanently growing technological interest, for example, as promising candidates for nanointerconnects in a high-speed electronics.

Coumarin-Phosphine-Based Smart Probes for Tracking Biologically Relevant Metal Complexes: From Theoretical to Biological Investigations

2016

International audience; Ten metal-based complexes and associated ligands have been synthesized and characterized. One of the metal ligands is a coumarin-phosphine derivative, which displays tunable fluorescence properties. The fluorescence is quenched in the case of the free ligand and ruthenium and osmium complexes, whereas it is strong for the gold complexes and phosphonium derivatives. These trends were rationalized by theoretical calculations, which revealed non-radiative channels involving a dark state for the free ligands that is lower in energy than the emissive state and is responsible for the quenching of fluorescence. For the Ru-II and Os-II complexes, other non-radiative channels…

Besançon: des défis à relever pour une nouvelle croissance

1997

Entre 1982 et 1990, la croissance de Besançon a été limitée: 3% contre 5,6 % pour l 'ensemble des unités urbaines françaises. Certes, on constate des difficultés similaires pour les villes dont la population est comprise entre 1 00 et 200 000 habitants. Pourtant, si Besançon n'est pas une très grande ville (au quarantième rang des agglomérations françaises). elle a l'avantage d'être une capitale régionale. Elle a pu ainsi bénéficier. plus que d'autres, du développement des activités tertiaires. Une croissance aussi modeste peut paraître surprenante.

Adipokines and lipoproteins: modulation by antihyperglycemic and hypolipidemic agents.

2014

Adipose tissue is an endocrine organ that secretes a number of hormones and metabolically active substances that impact energy metabolism and insulin sensitivity. These inflammatory markers are collectively referred to as adipocytokines, or adipokines. Adipose tissue's functional capacity and metabolic activity vary among individuals, thus partly explaining the incomplete overlap between obesity and the metabolic syndrome. The functional failure of adipose tissues results in changed energy delivery and impaired glucose consumption, triggering self-regulatory mechanisms to maintain homeostasis. Antihyperglycemic, hypolipidemic, antiobesity, and angiotensin II receptor blocker drugs influence…

Obesity and cardiovascular risk: a call for action from the European Society of Hypertension Working Group of Obesity, Diabetes and the High-risk Pat…

2018

: Obesity predisposes for atrial fibrillation, heart failure, sudden cardiac death, renal disease and ischemic stroke, which are the main causes of cardiovascular hospitalization and mortality. As obesity and the cardiovascular effects on the vessels and the heart start early in life, even from childhood, it is important for health policies to prevent obesity very early before the disease manifestation emerge. Key roles in the prevention are strategies to increase physical exercise, reduce body weight and to prevent or treat hypertension, lipids disorders and diabetes earlier and efficiently to prevent cardiovascular complications.

A Research Agenda: The Changing Relationship Between Body Weight and Health in Aging

2008

Testing Three Theories of Cognitive Dysfunction in Problem Alcohol Use

2014

- Objectives : many hypotheses concerning the cognitive functions affected by chronic alcoholism have been advanced. The aim of this study was to test cognitive performance in a sample of alcoholics and to examine results comparing three different models: the frontal lobe hypothesis, the lateralization hypothesis and the diffuse brain hypothesis. - Methods : 51 patients who refer to alcoholism service have been included in this study. Cognitive functions were assessed by trained psychologist with a specific neuropsychological battery. -Results : our results show a ranking of impairment degrees in different cognitive functions and different influence of clinical features. In our sample the f…

The role of Marine Protected Areas in influencing the invasion success of the alien crab Percnon gibbesi

2018

The biotic resistance hypothesis states that pristine communities, with high species richness and functional diversity, are less prone to biological invasions than species-poor areas either this is natural or it is a result of human activities. Complex communities with high levels of biodiversity, such as those hosted by Marine Protected Areas, should offer fewer niche opportunities (e.g. resources and space) to invasive species thereby reducing both their establishment possibilities and success (i.e. settlement and/or expansion). The present study aimed to evaluate the capacity of marine protected communities to provide a buffer against the establishment of one of the most invasive species…