Search results for "BES"
showing 10 items of 3692 documents
Branched-Chain Amino Acid Deprivation Decreases Lipid Oxidation and Lipogenesis in C2C12 Myotubes
2022
Impaired lipid metabolism is a common risk factor underlying several metabolic diseases such as metabolic syndrome and type 2 diabetes. Branched-chain amino acids (BCAAs) that include valine, leucine and isoleucine have been proven to share a role in lipid metabolism and hence in maintaining metabolic health. We have previously introduced a hypothesis suggesting that BCAA degradation mechanistically connects to lipid oxidation and storage in skeletal muscle. To test our hypothesis, the present study examined the effects of BCAA deprivation and supplementation on lipid oxidation, lipogenesis and lipid droplet characteristics in murine C2C12 myotubes. In addition, the role of myotube contract…
Aerobic exercise training and gut microbiome-associated metabolic shifts in women with overweight : a multi-omic study
2023
Physical activity is essential in weight management, improves overall health, and mitigates obesity-related risk markers. Besides inducing changes in systemic metabolism, habitual exercise may improve gut’s microbial diversity and increase the abundance of beneficial taxa in a correlated fashion. Since there is a lack of integrative omics studies on exercise and overweight populations, we studied the metabolomes and gut microbiota associated with programmed exercise in obese individuals. We measured the serum and fecal metabolites of 17 adult women with overweight during a 6-week endurance exercise program. Further, we integrated the exercise-responsive metabolites with variations in the gu…
La direttiva Mifid e l’obbligo di best execution
2009
La disciplina della libertà personale
2015
I congegni della libertà personale del minore incrociano temi cruciali nella prospettiva sovranazionale dei best interests of the child: la tutela della personalità fragile del minore che ha fatto ingresso nel circuito penale attraverso la più traumatica delle vicende, quella della compressione della libertà individuale, ha imposto modalità di gestione individualizzanti improntate all’insegna della più ampia flessibilità, dal “primo contatto” ai paradigmi della discrezionalità giudiziale nella modulazione delle vicende cautelari. Spiccano, tra tutti, gli equilibri difficili tra educazione e cautela, nell’orbita di un sistema normativo imperfetto, che una prassi illuminata ha saputo declinar…
Estudio del efecto de la cirugía de bypass gástrico en Y de Roux sobre los mecanismos moleculares asociados a la fisiopatología de la obesidad
2022
La obesidad es una enfermedad multifactorial e incapacitante que se caracteriza por una sobrecarga metabólica del tejido adiposo (AT), la inflamación crónica de bajo grado, el estrés oxidativo y la disfunción endotelial. En la actualidad, la prevalencia mundial de la obesidad está aumentando, donde el estilo de vida influye de manera significativa en la resolución de esta enfermedad. En este contexto, ha aumentado la demanda de estrategias para revertir las comorbilidades y frenar su aumento. El procedimiento de bypass gástrico en Y de Roux (RYGB) es una herramienta eficaz para la pérdida de peso y la remisión de las comorbilidades metabólicas de la obesidad, aunque se desconocen los mecani…
Le cimetière du second âge du Fer de Lailly au-delà de l'eau (Yonne) : découvertes anciennes et fouilles récentes
2023
Die Nekropole von Lailly Au-delà de l’Eau (Departement Yonne) war 1927 entdeckt worden und wurde1934, 1936 und 1937 und zum letzten Mal 2012 teilweise ausgegraben. Die Untersuchung der in den Depots der Museen von Senswiederentdeckten Grabbeigaben und die systematische Aufarbeitung der Grabungsarchive der Société archéologique de Sens habenes ermöglicht, einen Teil der geschlossenen Fundkontexte zu rekonstruieren und eine Belegungschronologie dieser kleinen Nekropolevorzuschlagen, deren großes wissenschaftliches Potenzial noch in situ erforscht werden muss. Die Studie der Grabsitten hat es zudemerlaubt, die Funde in den regionalen und überregionalen soziokulturellen Kontext zu einzuordnen
Una revisión crítica del debate sobre las necesidades humanas desde el enfoque centrado en la persona
2012
El artículo presenta algunos de los diferentes modelos teórico-explicativos sobre las necesidades humanas; revisa el estado del arte en las publicaciones recientes, y evalúa críticamente las limitaciones y potenciales que ellas tienen, desde una mirada sistémica y fenoménica desde un enfoque centrado en la persona. L’article présente certains des différents modèles théorico-explicatifs sur les besoins humains; il expose un état des lieux de la bibliographie récente, et évalue de manière critique les limites et potentiels que celles-ci peuvent représenter, dans une perspective systémique et propre au phénomène centrée sur la personne. The article presents some of the different theoretical-ex…
La formalisation fractale des tissus urbains
1998
The article concerns the fractal approach as it can bring new results making more understandable the morphology of agglomerate urban patterns. A new paradigm is developed, in order to improve the study of urban organizations according to optimization criteria. Specific fractal and multifractal methods are explicitated and applied to the knowledge of some big metropolitan areas and towns in Franche-Comté (France).
Obesity and functional gait recovery after total hip and total knee arthroplasties : clinical and biomechanical analysis
2018
Introduction : Body Mass Index (BMI) impact on gait recovery after total hip and total knee arthroplasty (THA and TKA) remains misunderstood. Few studies have analyzed the influence of BMI on the recovery of hip and knee range of motion (ROM) during gait or walking speed after THA and TKA. Our objective was to assess this impact preoperatively and post-operatively using both 3D gait analysis and clinical assessment. Our hypothesis was that obesity (BMI> 30kg /m2) would be a negative factor in the recovery of gait parameters.Material and methods: After conducting a systematic review of the literature on functional recovery after total prostheses of the lower limb (THA and TKA) to ensure the …
Les collections d’antiquités du Musée des Beaux-Arts et d’Archéologie de Besançon
2022
Dans cet article, nous proposons de partir à la découverte des collections d’antiquités du musée des Beaux-Arts et d’Archéologie de Besançon, l’un des plus anciens musées de France, issu du legs de l’abbé Boisot, daté de 1694, qui comprenait, outre la bibliothèque du cardinal de Granvelle, une collection de médailles et une vingtaine d’objets d’art, et a été récemment rénové . Nous avons choisi de nous concentrer sur quelques-uns des personnages qui, par leurs actions ou leurs donations, ont enrichi le musée entre les années 1870 et la première guerre mondiale. Le travail de recherche est en cours, mais nous souhaitons apporter ici un éclairage sur la collection d’antiquités d’un important …