Search results for "BIF"
showing 10 items of 539 documents
1988
Negatively charged lipid molecules were converted into polymerizable lipids by introduction of polymerizable mono- or bifunctional counterions. As an attempt to mimic the cytoskeleton of biomembranes, unsymmetrical polymeric vesicles were prepared, where the polyelectrolyte is attached either only to the inner or to the outer bilayer surfaces. Polymerizable cations were introduced to the outer surface of preformed small unilamellar vesicles via ion-exchange. The outer counterions of vesicles bearing polymerizable counterions at both sides of the membrane were replaced by Na+. Polymerization of these systems leads to unsymmetrical vesicles. The introduction, separation and polymerization of …
Bifunctional Acid-Base Catalysis
2011
Acid-base catalysis with bifunctional catalysts is a very prominent catalytic strategy in both small-molecule organocatalysts as well as enzyme catalysis. In both worlds, small-molecule catalysts and enzymatic catalysis, a variety of different general acids or hydrogen bond donors are used. In this chapter, important parallels between small molecule catalysts and enzymes are discussed, and a comparison is also made to the emerging field of frustrated Lewis pair catalysis.
Organocatalysts Fold to Generate an Active Site Pocket for the Mannich Reaction
2017
Catalysts containing urea, thiourea and tertiary amine groups fold into a three-dimensional organized structure in solution both in the absence as well as in the presence of substrates or substrate analogues, as indicated by solution NMR and computational studies. These foldamer catalysts promote Mannich reactions with both aliphatic and aromatic imines and malonate esters. Hammett plot and secondary kinetic isotope effects provide evidence for the C-C bond forming event as the turnoverlimiting step of the Mannich reaction. Computational studies suggest two viable pathways for the C-C bond formation step, differing in the activation modes of the malonate and imine substrates. The results sh…
Hidden attractors in Chua circuit: mathematical theory meets physical experiments
2022
AbstractAfter the discovery in early 1960s by E. Lorenz and Y. Ueda of the first example of a chaotic attractor in numerical simulation of a real physical process, a new scientific direction of analysis of chaotic behavior in dynamical systems arose. Despite the key role of this first discovery, later on a number of works have appeared supposing that chaotic attractors of the considered dynamical models are rather artificial, computer-induced objects, i.e., they are generated not due to the physical nature of the process, but only by errors arising from the application of approximate numerical methods and finite-precision computations. Further justification for the possibility of a real exi…
D3 Dihedral Logistic Map of Fractional Order
2021
In this paper, the D3 dihedral logistic map of fractional order is introduced. The map presents a dihedral symmetry D3. It is numerically shown that the construction and interpretation of the bifurcation diagram versus the fractional order requires special attention. The system stability is determined and the problem of hidden attractors is analyzed. Furthermore, analytical and numerical results show that the chaotic attractor of integer order, with D3 symmetries, looses its symmetry in the fractional-order variant.
Estrategias biotecnológicas para reducir el contenido en fitatos en productos fermentados de origen vegetal mediante fitasas de bifidobacterias
2015
Los alimentos integrales de origen vegetal, concretamente, los cereales de grano entero y leguminosas se caracterizan por ser una fuente excelente de fibra dietética y poseer un elevado contenido en compuestos fitoquímicos. Además de proporcionar macronutrientes, como carbohidratos complejos y proteínas, también destacan por su contenido en micronutrientes como son las vitaminas y minerales. Sin embargo, su ingesta conlleva a la vez un aporte en sustancias antinutritivas, como los fitatos, con gran afinidad por minerales, proteínas y elementos traza, que pueden comprometer su absorción por formación de quelatos estables en el tracto digestivo. Una hidrólisis o defosforilación parcial de los…
BIFOCAL PAIRS OF IMAGES FOR LOW-COST SURVEY IN CLOSE RANGE PHOTOGRAMMETRY
2019
Abstract. This paper present a method for close range photogrammetry based on an camera positioning scheme in which two cameras capture an equal portion of an object at the same scale, but have different focal lengths and camera-to-object distances. This scheme is alternative to the stereoscopic scheme and is associated with a system of equations which permits one to calculate first the relief displacement of points on a photograph and then their relief relative to a reference plane. The obtained relief and relief displacement values can be used to produce low-cost orthophotographs by using software for image processing, which doesn’t need to be dedicated, but has to provide measurement and…
Coronary bifurcations - anatomy, physiology and treatment with selected aspects of left main stem bifurcation
2021
Bifurkacja wieńcowa jest miejscem szczególnym w obrębie krążenia wieńcowego. Charakterystyczna anatomia oraz cechy przepływu krwi w złożony sposób wiążą się z rozmieszczeniem blaszek miażdżycowych. Wybór strategii leczenia zmian bifurkacji wieńcowych wymaga szczególnej uwagi, gdyż wszelkie powikłania w tym rejonie narażają na niedokrwienie istotnie większy obszar miokardium niż w przypadku pojedynczego naczynia. Niniejsza publikacja stanowi przegląd podstawowych informacji o anatomii, klasyfikacji oraz kolejnych krokach aktualnie zalecanych technik leczenia przezskórnego zmian bifurkacji wieńcowych, poczynając od kwalifikacji, przygotowania, poprzez wybór stentu, po optymalizację efektu zab…
Data from: Theoretical conditions for the coexistence of viral strains with differences in phenotypic traits: a bifurcation analysis
2018
We investigate the dynamics of a wild-type viral strain which generates mutant strains differing in phenotypic properties for infectivity, virulence, and mutation rates. We study, by means of a mathematical model and bifurcation analysis, conditions under which the wild-type and mutant viruses, which compete for the same host cells, can coexist. The coexistence conditions are formulated in terms of the basic reproductive numbers of the strains, a maximum value of the mutation rate, and the virulence of the pathogens. The analysis reveals that parameter space can be divided into five regions, each with distinct dynamics, that are organised around degenerate Bogdanov-Takens and zero-Hopf bifu…
Morelloflavone, a novel biflavonoid inhibitor of human secretory phospholipase A2 with anti-inflammatory activity
1997
Abstract The flavanonylflavone morelloflavone inhibited secretory phospholipase A 2 (PLA 2 ) in vitro , with a high potency on the human recombinant synovial and bee venom enzymes ( IC 50 = 0.9 and 0.6 μM, respectively). The inhibition was apparently irreversible. In contrast, the compound was inactive on cytosolic PLA 2 activity from human monocytes. Morelloflavone scavenged reactive oxygen species generated by human neutrophils ( IC 50 = 2.7 and 1.8 μM for luminol and lucigenin, respectively) but did not modify cellular responses such as degranulation or eicosanoid release. This biflavonoid exerted anti-inflammatory effects in animal models, with a potent inhibition of 12-O-tetradecanoylp…