Search results for "BIOS"

showing 10 items of 2557 documents

Benefits of immune protection versus immunopathology costs: a synthesis from cytokine KO models.

2017

5 pages; International audience; The inflammatory response can produce damage to host tissues and in several infectious diseases the most severe symptoms are due to immunopathology rather than a direct effect of pathogen multiplication. One hypothesis for the persistence of inflammatory damage posits that the benefits of protection towards infection outweigh the costs. We used data on knocked-out (KO) cytokine models [and the corresponding wild-type (WT) controls] to test this hypothesis. We computed differences in pathogen load and host survival between WT and KO and divided them by the WT values. Using this ratio provides an internal control for variation in pathogen species, host strain,…

0106 biological sciences0301 basic medicineMicrobiology (medical)medicine.medical_treatmentVirulenceInflammationImmunopathologyBiologyCommunicable Diseases010603 evolutionary biology01 natural sciencesMicrobiologyPersistence (computer science)Gene Knockout Techniques03 medical and health sciencesImmunopathologyGeneticsmedicine[ SDV.EE.IEO ] Life Sciences [q-bio]/Ecology environment/SymbiosisAnimalsHumans[ SDV.IMM ] Life Sciences [q-bio]/ImmunologyMolecular BiologyPathogenCytokineEcology Evolution Behavior and SystematicsInflammationVirulenceHost (biology)Immune protectionHost survivalComputational BiologyPathogen loadDisease Models Animal030104 developmental biologyInfectious DiseasesCytokineHost-Pathogen InteractionsImmunologyCytokinesmedicine.symptom
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Nitric oxide: a multitask player in plant–microorganism symbioses

2016

Symbiosis is a close and often long-term interaction between two different biological organisms, i.e. plants or fungi and microorganisms. Two main types of plant–microorganism interactions, mutualistic and cooperative, have been categorized. Mutualistic interactions, including nitrogen-fixing and mycorrhizal symbioses, refer to mostly obligate relationships between a host plant and a symbiont microorganism. Cooperative interactions correspond to less obligate and specific relationships. They involve microorganisms, referred to as plant growth-promoting rhizobia (PGPR), able to colonize root surface or inner tissues. Lichens are symbiotic associations of host fungi and photosynthetic partner…

0106 biological sciences0301 basic medicineMicroorganism[SDV]Life Sciences [q-bio]LichenBiology01 natural sciencesRhizobia03 medical and health sciencesinteraction microorganisme végétalSymbiosisNitrogen fixationnitric oxideBotanyPlant symbiosisMycorrhizamicrobiologieLichenoxyde nitriqueObligateEcologyHost (biology)fungifood and beveragesbiology.organism_classificationsymbiosisLegume030104 developmental biologyNitrogen fixationPlant growth-promoting rhizobia (PGPR)MycorrhizasymbioseLegume Lichen Mycorrhiza Nitric oxide Nitrogen fixation Plant growth-promoting rhizobia (PGPR) Plant symbiosis Rhizobium010606 plant biology & botanyRhizobium
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Phosphoglycerate dehydrogenase genes differentially affect Arabidopsis metabolism and development.

2021

[EN] Unlike animals, plants possess diverse L-serine (Ser) biosynthetic pathways. One of them, the Phosphorylated Pathway of Serine Biosynthesis (PPSB) has been recently described as essential for embryo, pollen and root development, and required for ammonium and sulfur assimilation. The first and rate limiting step of PPSB is the reaction catalyzed by the enzyme phosphoglycerate dehydrogenase (PGDH). In Arabidopsis, the PGDH family consists of three genes, PGDH1, PGDH2 and PGDH3. PGDH1 is characterized as being the essential gene of the family. However, the biological significance of PGDH2 and PGDH3 remains unknown. In this manuscript, we have functionally characterized PGDH2 and PGDH3. Ph…

0106 biological sciences0301 basic medicineMutantArabidopsisPlant ScienceGenes Plant01 natural sciencesGene Expression Regulation EnzymologicSerine03 medical and health scienceschemistry.chemical_compoundSulfur assimilationBiosynthesisGene Expression Regulation PlantArabidopsisGeneticsSerinePhosphoglycerate dehydrogenaseGenePhosphoglycerate DehydrogenasePSPbiologyGeneral MedicinePhosphorylated pathway of serine biosynthesisbiology.organism_classificationBiosynthetic Pathways030104 developmental biologyPGDHBiochemistrychemistryEssential geneFISIOLOGIA VEGETALPhosphoserine phosphataseAgronomy and Crop Science010606 plant biology & botanyPlant science : an international journal of experimental plant biology
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Defense Priming in Nicotiana tabacum Accelerates and Amplifies ‘New’ C/N Fluxes in Key Amino Acid Biosynthetic Pathways

2020

: In the struggle to survive herbivory by leaf-feeding insects, plants employ multiple strategies to defend themselves. One mechanism by which plants increase resistance is by intensifying their responsiveness in the production of certain defense agents to create a rapid response. Known as defense priming, this action can accelerate and amplify responses of metabolic pathways, providing plants with long-lasting resistance, especially when faced with waves of attack. In the work presented, short-lived radiotracers of carbon administered as 11CO2 and nitrogen administered as 13NH3 were applied in Nicotiana tabacum, to examine the temporal changes in &lsquo

0106 biological sciences0301 basic medicineNicotiana tabacumamino acid metabolismPlant Science01 natural sciencesplant insect herbivorySerine03 medical and health scienceschemistry.chemical_compoundBiosynthesislcsh:Botanynitrogen-13Shikimate pathwaycarbon-11Secondary metabolismEcology Evolution Behavior and SystematicsX-ray fluorescence imagingchemistry.chemical_classificationEcologybiologydefense primingJasmonic acidfungifood and beveragesbiology.organism_classificationlcsh:QK1-989Amino acidMetabolic pathway030104 developmental biologychemistryBiochemistryisotope ratio analysis010606 plant biology & botanyPlants
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The specific role of plastidial glycolysis in photosynthetic and heterotrophic cells under scrutiny through the study of glyceraldehyde-3-phosphate d…

2016

The cellular compartmentalization of metabolic processes is an important feature in plants where the same pathways could be simultaneously active in different compartments. Plant glycolysis occurs in the cytosol and plastids of green and non-green cells in which the requirements of energy and precursors may be completely different. Because of this, the relevance of plastidial glycolysis could be very different depending on the cell type. In the associated study, we investigated the function of plastidial glycolysis in photosynthetic and heterotrophic cells by specifically driving the expression of plastidial glyceraldehyde-3-phosphate dehydrogenase (GAPCp) in a glyceraldehyde-3-phosphate de…

0106 biological sciences0301 basic medicineNitrogenArabidopsisDehydrogenasePlant Science01 natural sciencesPlant RootsSerine03 medical and health scienceschemistry.chemical_compoundBiosynthesisSerineGlycolysisPlastidsPlastidPhosphorylationPhotosynthesisGlyceraldehyde 3-phosphate dehydrogenasebiologyGlyceraldehyde-3-Phosphate DehydrogenasesCompartmentalization (fire protection)CarbonArticle AddendumCytosol030104 developmental biologychemistryBiochemistryMutationbiology.proteinGlycolysis010606 plant biology & botany
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The phosphorylated pathway of serine biosynthesis links plant growth with nitrogen metabolism

2021

Abstract Because it is the precursor for various essential cellular components, the amino acid serine is indispensable for every living organism. In plants, serine is synthesized by two major pathways: photorespiration and the phosphorylated pathway of serine biosynthesis (PPSB). However, the importance of these pathways in providing serine for plant development is not fully understood. In this study, we examine the relative contributions of photorespiration and PPSB to providing serine for growth and metabolism in the C3 model plant Arabidopsis thaliana. Our analyses of cell proliferation and elongation reveal that PPSB-derived serine is indispensable for plant growth and its loss cannot b…

0106 biological sciences0301 basic medicineNitrogenPhysiologyNitrogen assimilationCell RespirationArabidopsisPlant DevelopmentPlant Science01 natural sciencesSerine03 medical and health scienceschemistry.chemical_compoundPlant Growth RegulatorsBiosynthesisGlutamine synthetaseSerineGeneticsPhosphorylationResearch ArticlesCell Proliferationchemistry.chemical_classificationbiologyChemistryMetabolismBiosynthetic PathwaysAmino acid030104 developmental biologyBiochemistrybiology.proteinPhotorespirationGlutamine oxoglutarate aminotransferase010606 plant biology & botanyPlant Physiology
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Females pay the oxidative cost of dominance in a highly social bird.

2018

12 pages; International audience; Understanding the evolution and maintenance of social behaviour requires a better understanding of the physiological mechanisms underlying the trade-offs between the benefits and costs of social status. Social dominance is expected to provide advantages in terms of access to resources and to reproduction but acquiring and maintaining dominance may also entail physiological costs. Dominant individuals are likely to engage more frequently in aggressive behaviours and/or may allocate a substantial amount of energy and resources to signal their status. Hence, dominance is likely to involve multiple physiological processes that stimulate aerobic metabolism and l…

0106 biological sciences0301 basic medicineOXYsocial dominanceOxidative phosphorylationSocial behaviourBiologyphysiological costsTrade-offmedicine.disease_cause010603 evolutionary biology01 natural sciences03 medical and health sciencesFemale healthmedicineoxidative stressEcology Evolution Behavior and Systematicstrade-offPhiletairus socius030104 developmental biologyDominance (ethology)AgeingROMsAnimal Science and Zoology[SDE.BE]Environmental Sciences/Biodiversity and EcologyOxidative stressDemographySocial status[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/Symbiosis
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Opportunity costs resulting from scramble competition within the choosy sex severely impair mate choosiness.

2016

12 pages; International audience; Studies on mate choice mainly focus on the evolution of signals that would maximize the probability of finding a good-quality partner. Most models of sexual selection rely on the implicit assumption that individuals can freely compare and spot the best mates in a heterogeneous population. Comparatively few studies have investigated the consequences of the mate-sampling process. Several sampling strategies have been studied from theoretical or experimental perspectives. They belong to two families of decision rules: best-of-n strategies (individuals sample n partners before choosing the best one within this pool) or threshold strategies (individuals sequenti…

0106 biological sciences0301 basic medicineOpportunity costmate-sampling strategyPopulationSample (statistics)010603 evolutionary biology01 natural sciencesEvolutionarily stable strategy03 medical and health sciences[ SDV.EE.IEO ] Life Sciences [q-bio]/Ecology environment/SymbiosisEconometricseducationintrasexual competitionEcology Evolution Behavior and Systematics[ SDE.BE ] Environmental Sciences/Biodiversity and Ecologyeducation.field_of_studythreshold decision rulechoosinessDecision rule030104 developmental biologyMate choiceSexual selectionAnimal Science and Zoologyopportunity costs[SDE.BE]Environmental Sciences/Biodiversity and EcologyPsychologyScramble competitionSocial psychology[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/Symbiosis
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Evidence for Succession and Putative Metabolic Roles of Fungi and Bacteria in the Farming Mutualism of the Ambrosia Beetle Xyleborus affinis.

2020

The bacterial and fungal community involved in ambrosia beetle fungiculture remains poorly studied compared to the famous fungus-farming ants and termites. Here we studied microbial community dynamics of laboratory nests, adults, and brood during the life cycle of the sugarcane shot hole borer, Xyleborus affinis. We identified a total of 40 fungal and 428 bacterial operational taxonomic units (OTUs), from which only five fungi (a Raffaelea fungus and four ascomycete yeasts) and four bacterial genera (Stenotrophomonas, Enterobacter, Burkholderia, and Ochrobactrum) can be considered the core community playing the most relevant symbiotic role. Both the fungal and bacterial populations varied s…

0106 biological sciences0301 basic medicinePhysiologyAmbrosia fungimicrobiomeFungicultureFungusBiologyAmbrosia beetle010603 evolutionary biology01 natural sciencesBiochemistryMicrobiologyHost-Microbe Biology03 medical and health sciencesmycobiomeSymbiosisBotanyGeneticsAmbrosiaInternal transcribed spacerXyleborus affinisMolecular BiologyEcology Evolution Behavior and SystematicsMutualism (biology)fungibiology.organism_classificationQR1-502Computer Science Applications030104 developmental biologyModeling and SimulationResearch Article
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Ammonium acts systemically while nitrate exerts an additional local effect on Medicago truncatula nodules

2020

National audience; Symbiotic nitrogen fixation (SNF) has a high energetic cost for legume plants; legumes thus reduce SNF when soil N is available. The present study aimed to increase our understanding regarding the impacts of the two principal forms of available N in soils (ammonium and nitrate) on SNF. We continuously measured the SNF of Medicago truncatula under controlled conditions. This permitted nodule sampling for comparative transcriptome profiling at points connected to the nodules' reaction following ammonium or nitrate applications. The N component of both ions systemically induced a rhythmic pattern of SNF, while the activity in control plants remained constant. This rhythmic a…

0106 biological sciences0301 basic medicinePlant Sciencenodule activity01 natural sciencesNicotianamine synthaseTranscriptome03 medical and health scienceschemistry.chemical_compoundNitratenitrateRNA seqAmmonium CompoundsMedicago truncatulaGeneticsAmmoniumLeghemoglobinSymbiosisLegumeNitratesbiologyNCR peptidesfungiGeneral MedicineneNASbiology.organism_classificationMedicago truncatula030104 developmental biologychemistryBiochemistrynitrogen fixation[SDE]Environmental SciencesNitrogen fixationbiology.proteinRoot Nodules PlantAgronomy and Crop Science010606 plant biology & botany
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