Search results for "BM"
showing 10 items of 1459 documents
Thermomechanical analyses of the DEMO-HCPB TBM medium scale mock-up to be tested in the HE-FUS3 facility
2000
On the nuclear response of the HCLL-TBM in ITER-FEAT
2003
On the nuclear impact of different coolants in the HCLL-TBM in ITER-FEAT
2003
Hydraulic Analysis of the CDR Design of the ITER TBM Port Plug
2013
Rôle du transporteur d'acides aminés Minidiscs dans le fonctionnement du système nerveux chez Drosophila melanogaster
2015
Amino acids have many functions in the body in addition to their role as basic constituents of proteins. They can for example serve as a neurotransmitter or signal for the activation of intracellular pathways. Carriers of the SLC protein family facilitate their path through the plasma membrane. The heterodimeric amino acid transporters HAT belong to SLC proteins. HAT are composed of a light chain SLC7 ensuring the specificity of transport and a heavy chain SLC3 involved in the addressing of the protein complex to the plasma membrane. My thesis focused on studying the role of a SLC7 homologue in drosophila, Minidiscs (Mnd), in the functioning of the nervous system. Mnd might belong to system…
The columnar gene vnd is required for tritocerebral neuromere formation during embryonic brain development of Drosophila.
2006
International audience; In Drosophila, evolutionarily conserved transcription factors are required for the specification of neural lineages along the anteroposterior and dorsoventral axes, such as Hox genes for anteroposterior and columnar genes for dorsoventral patterning. In this report, we analyse the role of the columnar patterning gene ventral nervous system defective (vnd) in embryonic brain development. Expression of vnd is observed in specific subsets of cells in all brain neuromeres. Loss-of-function analysis focussed on the tritocerebrum shows that inactivation of vnd results in regionalized axonal patterning defects, which are comparable with the brain phenotype caused by mutatio…
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
2013
AM Vicente - Cross-Disorder Group of the Psychiatric Genomics Consortium Most psychiatric disorders are moderately to highly heritable. The degree to which genetic variation is unique to individual disorders or shared across disorders is unclear. To examine shared genetic etiology, we use genome-wide genotype data from the Psychiatric Genomics Consortium (PGC) for cases and controls in schizophrenia, bipolar disorder, major depressive disorder, autism spectrum disorders (ASD) and attention-deficit/hyperactivity disorder (ADHD). We apply univariate and bivariate methods for the estimation of genetic variation within and covariation between disorders. SNPs explained 17-29% of the variance in …
A neutron point kinetic model for fusion relevant calculations
2012
Abstract In the framework of research activities on fusion reactors a great effort is dedicated by the scientific community to the development of tritium breeding blankets. One of the main goals is to assess the neutronic behaviour of such devices to analyse their tritium breeding performance and to evaluate the required data for their thermal–mechanic and thermal–hydraulic design. Many papers have been published on this topic considering some stationary condition to calculate such important quantities as heating power, gas production and dpa rates, tritium breeding ratio, etc., but not much attention has been focussed to neutronic transport analyses in transient conditions. The present pap…
Conceptual and epistemological difficulties of future teachers of physics and chemistry in the energetic explanations of physical and chemical phenom…
2016
En este trabajo analizamos las dificultades conceptuales y epistemológicas que tienen sobre termoquímica estudiantes universitarios de los últimos cursos de Física, Química e Ingeniería Química. Para ello se han aplicado a una muestra de 35 de estos futuros profesores dos cuestionarios sobre efectos térmicos en fenómenos físicos y químicos que han de explicar y se han categorizado sus respuestas según los razonamientos usados. Se ha constatado que la mayoría de los estudiantes no saben delimitar en el nivel macroscópico los sistemas que interaccionan, no utilizan el concepto de energía interna ni la primera ley de la termodinámica en los procesos físicos y químicos. Muy pocos de estos profe…
Stochastic response of offshore structures by a new approach to statistical cubicization
2001
This study presents a new statistical cubicization approach for predicting the stochastic response of offshore platforms subjected to a Morison-type nonlinear drag loading. Statistics of the original system are obtained from an equivalent nonlinear system, which is constructed by replacing the Morison drag force by a cubic polynomial function of the relative fluid-structure velocity, up to cubic order. A Volterra series expansion with a finite Fourier series representation is used to approximate the response of the equivalent system. Exact solutions are developed to express the Fourier coefficients of the second and third-order response as functions of the Fourier coefficients of the first-…