Search results for "BMPs"
showing 5 items of 5 documents
Current European approaches in highway runoff management: A review
2022
Highway runoff is one of the most significant non-point sources of pollution for the terrestrial and aquatic environment with biological, physical, and chemical effects. Considering local characteristics, treatment practices, and determining factors are essential for highway runoff management. The aim of this paper is to survey the review of highway runoff management in Europe with emphasis on runoff characterization, treatment, and modeling approaches and identifying possible knowledge gaps exists based on our review. The results showed that highway runoff has spatiotemporal variation, which is the main factor in the regional selection of the best management practice (BMP). Also, recent st…
Capitolo 12 - Interventi per il trattamento delle acque di pioggia
2014
BMP7v induces cancer stem cells differentiation and enhances chemotherapy response in colorectal cancer
2014
Cancer stem cells (CSCs), characterized by high levels of ATP-binding cassette, anti-apoptotic molecules, active DNA-repair and slow replication capacities, surviving to conventional anti-cancer therapies, able to eradicate only the highly proliferating tumor cells, represent the elective target for new therapies. Colorectal CSCs (CR-CSCs) represent a powerful tool for preclinical validation of target therapies. In particular the elucidation of the mechanisms that govern stem cell survival and differentiation appears very essential for the identification of new molecular targets in cancer therapy. Among the molecules that govern these processes there are the Bone Morphogenetic Proteins (BMP…
Papel de las proteínas BMPs en la regulación de la neurogénesis hipocampal adulta
2022
En determinadas regiones del cerebro de los mamíferos, nuevas neuronas nacen a lo largo de la vida del individuo debido a la existencia de células madre neurales (NSCs). La neurogénesis en el cerebro adulto ocurre en dos zonas determinadas: la zona subventricular (ZSV) de los ventrículos laterales y la zona subgranular (ZSG) del giro dentado del hipocampo. Señales locales, como los ligandos de la familia de las Wnt, regulan la proliferación y diferenciación de las NSCs. Otras señales, como las Proteínas Morfogenéticas de Hueso (BMPs), están implicadas en el mantenimiento de la quiescencia de las NSCs. Sin embargo, los mecanismos moleculares que subyacen a este proceso no están tot…
Stormwater Source Control as a Strategy for Sustainable Development: State of the Practice and Perceived Trends
2005
The primary objective of the paper is to draw upon the experiences acquired in many parts of the world to provide an up-to-date summary of the state of the practice for source control techniques and approaches, in a sustainable development context. After a discussion of the prevailing context for urban drainage approaches, three main themes covering techniques and design criteria, institutional aspects and performance issues are discussed relative to source control implementation. The discussion is based on findings from the compilation and analysis of available literature, recently developed databases, the experience of the different members of the SOCOMA group and recent research on desig…