Search results for "BOC"
showing 7 items of 477 documents
Trombocitozes saistība ar ne-sīkšūnu plaušu vēža pacientu demogrāfiskajiem un klīniskajiem faktoriem
2019
Ievads. Lai gan tiek izstrādātas arvien efektīvākas ļaundabīgo audzēju agrīnas skrīninga un diagnostikas metodes, ne-sīkšūnu plaušu vēzis vēl joprojām pārsvarā tiek atklāts III vai IV stadijā, līdz ar to tas ir viens no vadošajiem audzējiem mirstības ziņā. Trombocīti piedalās vēža šūnu augšanā un tālākā izplatīšanā pa organismu. Ne-sīkšūnu plaušu vēža pacientiem bieži ir palielināts trombocītu skaits, kas ir saistīts ar sliktu prognozi. Tamdēļ, ir būtiski noskaidrot vai pastāv kādi ne-sīkšūnu plauša vēža pacienta demogrāfiskie vai klīniskie rādītāji, kam ir korelācija ar trombocitozi. Tas ļautu laicīgi paredzēt to, ka pacientam iespējams būs palielināts trombocītu skaits un izrietoši sliktā…
THE RELATIONSHIP BETWEEN UNEMPLOYMENT AND INFLATION IN POLAND AND THE PHILLIPS CURVE
2018
W części teoretycznej artykułu przedstawiono ewolucję poglądów na temat krzywej Phillipsa. Przybliżono model A. W. Phillipsa z 1958 r., a także liczne rozwinięcia tego modelu autorstwa takich ekonomistów, jak: P. Samuelson, R. Solow, M. Friedman, E. Phelps, R. Lucas, E. Kydland i E. Prescott. Wprowadzenie teoretyczne dopełnia przegląd dotychczasowego dorobku literatury światowej z zakresu weryfikacji empirycznej krzywej Phillipsa. Celem części empirycznej niniejszej pracy jest zbadanie istnienia krzywej Phillipsa w gospodarce polskiej w latach 1990-2010. Sprawdzono kierunek i siłę związku stóp inflacji i bezrobocia na podstawie danych miesięcznych, kwartalnych, półrocznych i rocznych. W bad…
Determinantes del Marketing Boca a Boca en el Contexto Universitario: El Rol de la Satisfacción y la Lealtad de los Estudiantes
2019
espanolEste articulo analiza los antecedentes del Marketing Boca a Boca en el contexto de instituciones de educacion superior en Chile. El modelo de investigacion propone como antecedentes del Marketing Boca a Boca la satisfaccion y la lealtad de los estudiantes. Establece tambien que la variable satisfaccion de los estudiantes es influenciada por las variables imagen y valor percibido de la Universidad. A partir de una muestra de 317 estudiantes y aplicando SMARTPLS 3.0, se confirmaron todas las relaciones propuestas en el modelo, siendo la satisfaccion el principal antecedente en este contexto de Marketing Boca a Boca EnglishThis article analyzes the characteristics of Word of Mouth marke…
Platelet cut-off for anticoagulant therapy in thrombocytopenic patients with blood cancer and venous thromboembolism: an expert consensus
2019
Background. Management of venous thromboembolism (VTE) in patients with haematologic malignancies and thrombocytopenia is clinically challenging due to the related risks. No prospective studies or clinical trials have been carried out and, therefore, no solid evidence on this compelling issue is available. Methods. Given this, an expert panel endorsed by the Gruppo Italiano Malattie Ematologiche dell'Adulto Working Party on Thrombosis and Haemostasis was set up to produce a formal consensus, according to the RAND method, in order to issue clinical recommendations about the platelet (PLT) cut-off for safe administration of low molecular weight heparin (LMWH) in thrombocytopenic (PLT <100×…
New developments in the management of hepatitis C virus infection: focus on boceprevir
2012
Chronic hepatitis C virus infection is an important public health problem, and the standard treatment (combination of pegylated interferon-α and ribavirin) has an effectiveness rate of only 40%-50%. Novel virus-specific drugs have recently been designed, and multiple compounds are under development. The approval for the clinical use of direct-acting antivirals in 2011 (boceprevir [BOC] and telaprevir, viral NS3 protease inhibitors) has increased recovery rates by up to 70%. Therefore, a highly effective treatment has been envisioned for the first time. This paper focuses on BOC and the implementation of new BOC-based treatment regimes.
Synergistic effect of W incorporation and pulsed current mode on wear and tribocorrosion resistance of coatings grown by plasma electrolytic oxidatio…
2019
Ceramic coatings were grown by plasma electrolytic oxidation on 7075 Al alloy using unipolar and bipolar pulsed current waveforms with 20 and 40% cathodic duty cycles, from a silicate-based bath without and with the addition of Na2WO4. Pancake-like morphology was dominant on the coatings grown by unipolar waveform, while the bipolar waveforms promoted volcano-like morphology, increased the roughness of the coating surface and the formation of more compact layers. The coatings produced using the bipolar waveforms provided higher resistances toward both tribocorrosion and dry sliding conditions, while further improvement was achieved by the presence of tungsten. The coatings produced in tungs…