Search results for "BREAST"
showing 10 items of 1871 documents
NF-κB is a potential pharmacological target in triple negative breast cancers.
2015
Triple negative breast cancers (TNBCs), characterized by lack of estrogen, progesterone and HER2 receptors, are a highly heterogenous group of tumors which account for about 20% to 25% of all breast cancers. TNBCs are often associated with epithelial-mesenchymal transition and a high propensity for early metastasis. Since no molecularly-targeted therapeutic agents are clinically available for TNBCs, these tumors, which are frequently resistant to cytotoxic chemotherapy, remain difficult to treat. Nevertheless, progress is being made in the finding of molecular alterations typical of TNBCs toward which to focus therapeutic efforts.
Dynamics of natural hemiboreal woodland in the Moricsala Reserve, Latvia: the studies of K. R. Kupffer revisited
2010
Abstract Karl Reinhold Kupffer (1872–1935), an outstanding botanist and plant ecologist, took the initiative that led to the establishment of the first nature reserve in Latvia, on Moricsala Island in 1912. The reserve provided an excellent reference area for natural hemiboreal woodland for future generations. There have been very few studies on the dynamics of natural broadleaved forest in Europe, probably owing to lack of primeval forests of this type. However, Kupffer produced a map of forest types in the reserve with accurate descriptions of the vegetation by layers, and his descriptions include interpretations of forest dynamics processes. This information, together with the present ag…
Usefulness of SonoVue in the identification of sentinel nodes in patients with breast cancer
2013
Purpose Methods and Materials Results Conclusion References Personal Information
Primary neuroendocrine carcinoma of the breast: A single Center experience and review of the literature
2017
Neuroendocrine carcinoma of the breast is an extremely rare tumor. A standard treatment has yet to be established because only a few cases have been reported in literature. The authors report five cases observed from January 2007 to December 2014 and a review of literature. Four patients underwent quadrantectomy and in two cases axillary nodal dissection and only one to mastectomy with axillary nodal dissection. Tumor size was from T1 to T2 with N0 to N1, according TNM classification. Pathological specimens were stained with hematoxylin and eosin and an immunohistochemical panel of antibodies (Neuron-specific enolase, Chromogranin, Synaptophysin, Estrogen and Progesterone receptors, c-erb a…
Adherence to the New Nordic Diet during pregnancy and subsequent maternal weight development: a study conducted in the Norwegian Mother and Child Coh…
2018
AbstractThe rising prevalence of overweight and obesity is a worldwide public health challenge. Pregnancy and beyond is a potentially important window for future weight gain in women. We investigated associations between maternal adherence to the New Nordic diet (NND) during pregnancy and maternal BMI trajectories from delivery to 8 years post delivery. Data are from the Norwegian Mother and Child Cohort. Pregnant women from all of Norway were recruited between 1999 and 2008, and 55 056 are included in the present analysis. A previously constructed diet score, NND, was used to assess adherence to the diet. The score favours intake of Nordic fruits, root vegetables, cabbages, potatoes, oatme…
Nipple-sparing mastectomy and breast reconstruction with a deep inferior epigastric perforator flap using thoracodorsal recipient vessels and a low l…
2018
Background Nipple-sparing mastectomy poses challenges in providing esthetically-pleasing immediate autologous breast reconstruction. This study was to investigate the outcomes of nipple-sparing mastectomy with breast reconstruction using free abdominal flaps between two different recipient sites. Methods Between 2010 and 2016, 79 patients who underwent nipple-sparing mastectomy with autologous breast reconstruction using thoracodorsal (TD) vessels in 30 cases or internal mammary (IM) vessels in 49 cases were investigated. Demographics, intraoperative findings, complications, and quality of life using Breast-Q questionnaire were compared between two groups. Results All flap survived. There w…
Social Vision on Wet Nurses in the [Spanish] Newspaper “La Vanguardia” (1881-1908)
2017
Históricamente ha habido situaciones y momentos en que las madres han delegado el proceso de lactancia en nodrizas. En el siglo XIX las nodrizas fueron representadas en la prensa española reproduciendo los esquemas del modelo social androcéntrico imperante. Se pretende describir y categorizar la visión de la nodriza reflejada en la prensa española mediante el análisis de contenido de las fuentes periodísticas de este período. La conclusión alcanzada han sido que la prensa refleja la importancia social de la nodriza como un elemento normalizado en la sociedad con un papel fundamental en los aspectos demográficos de la sociedad, estableciendo una visión dual en función del grupo social al que…
In-witro-NMR-Spektroskopie an gesunden, mastopathisch veränderten und karzinomatös befallenen Brustdrüsen-gewebsproben, korreliert mit histologischen…
1994
Es wurden bei 57 Patientinnen mit klinischem Verdacht auf Mammakarzinom 121 Gewebeproben entnommen und mittels der 1H-NMR-Spektroskopie bei 300 MHz in vitro nach Korrelation mit histologischen Befunden untersucht. Im interessanten Spektralbereich zwischen 2,7 und 4,1 ppm wurden starke Signale beobachtet, die Fett, (Phosphoryl-)Cholin, Kreatin(-phosphat) sowie Karnitin zugeordnet wurden. Weiterhin konnten mit hoher Regelmasigkeit 8 schwachere, zum Teil uberlappende Signale der Substanzen Glukose, Glyzin, Threonin, Serin, Inositol und Saccharose nachgewiesen werden. Hierbei wurden Linienintensitaten uber ein iteratives Fitprogramm bestimmt. Uber deren Quotienten konnten unterschiedliche Geweb…
A whey-predominant formula induces fecal microbiota similar to that found in breast-fed infants
2007
To compare the effects of a whey-predominant infant formula and breast milk on the gut microbiota, growth, and tolerance of infants, we conducted an open, prospective, parallel-group study in healthy newborn infants. A total of 60 infants were enrolled, and 55 completed the study. Of the 55 infants, 21 were breast-fed and 34 were fed a whey-predominant study formula that had low phosphate concentration (31 mg/100 kcal), was reduced in protein (1.8 g/100 kcal or 0.43 g/kJ), had lactose as the sole carbohydrate source, and had an amino acid profile and buffering capacity similar to that of human milk. At 30 and 60 days of age, fecal bacterial counts were determined using fluorescence in situ …
Vitamin E as an IgE inhibitor: stability during cold storage of human milk
2008
Human breast milk is recommended as the unique food for neonates based on its known properties. When the production of milk by themother is not suf cient or the mother is not able to feed her child for professional reasons, milk banks or the mothers practice ofcollecting their own milk are the existing alternatives for breast-feeding. In both situations cold storage (refrigeration or freezing) can beused in neonatal units, at home and in human milk banks