Search results for "BREAST"

showing 10 items of 1871 documents

Biomonitoring of bisphenols A, F, S and parabens in urine of breastfeeding mothers: Exposure and risk assessment

2019

In the present study we used human biomonitoring to assess the internal exposure and the risk to four parabens and three bisphenols in 103 Spanish breastfeeding mothers participating in the BETTERMIILK project. Urinary methylparaben (MP), ethylparaben (EP), propylparaben (PP) and butylparaben (BP) presented detection frequencies ranging from 12% (BP) to 92% (MP), while bisphenol A (BPA), bisphenol F (BPF) and bisphenol S (BPS) were detected in 76% (BPA) and 20% (BPF, BPS) of the mothers. Average paraben concentrations (geometric mean) ranged from 0.021 ng mL(-1) (BP) to 17.7 ng mL(-1) (MP), whereas bisphenols had geometric means concentrations from 0.042 ng mL(-1) (BPF) to 0.927 ng mL(-1) (…

PopulationMothersParabensContext (language use)BisphenolsUrineUrine010501 environmental sciencesRisk Assessment01 natural sciencesBiochemistry03 medical and health scienceschemistry.chemical_compound0302 clinical medicinePhenolsHumansMedicine030212 general & internal medicineFood scienceBenzhydryl CompoundsEthylparabeneducation0105 earth and related environmental sciencesGeneral Environmental ScienceBreastfeeding mothersButylparabeneducation.field_of_studyMethylparabenbusiness.industryParabenBreast FeedingchemistryBisphenol SBiomonitoringFemalebusinessBiological MonitoringEnvironmental Research
researchProduct

Spanish Menopause Society position statement: Use of denosumab in postmenopausal women

2014

Denosumab is a new drug developed for the treatment of osteoporosis. Moreover, increasing evidences link denosumab with benefits in cancer, an area of interest for those in charge of the postmenopausal health. Denosumab has shown efficacy in the control of bone loss associated with hypogonadic states created by chemotherapy in breast and other cancers. Moreover, some studies reveal efficacy in reducing the progression of metastases. A panel of experts from the Spanish Menopause Society has met to develop usage recommendations based on the best available evidence.

Position statementOncologymedicine.medical_specialtyInjections SubcutaneousOsteoporosisBone NeoplasmsBreast NeoplasmsGeneral Biochemistry Genetics and Molecular BiologyFractures BoneBreast cancerBone DensityInternal medicinemedicineHumansOsteoporosis PostmenopausalPostmenopausal womenBone Density Conservation Agentsbusiness.industryObstetrics and GynecologyCancerArea of interestmedicine.diseasePostmenopauseMenopauseDenosumabDisease ProgressionPhysical therapyFemaleBone RemodelingDenosumabSafetybusinessmedicine.drugMaturitas
researchProduct

Breastfeeding and COVID-19 vaccination: position statement of the Italian scientific societies

2021

AbstractThe availability of a COVID-19 vaccine has raised the issue of its compatibility with breastfeeding. Consequently, the Italian Society of Neonatology (SIN), the Italian Society of Pediatrics (SIP), the Italian Society of Perinatal Medicine (SIMP), the Italian Society of Obstetrics and Gynecology (SIGO), the Italian Association of Hospital Obstetricians-Gynecologists (AOGOI) and the Italian Society of Infectious and Tropical Diseases (SIMIT) have made an ad hoc consensus statement. Currently, knowledge regarding the administration of COVID-19 vaccine to the breastfeeding mother is limited. Nevertheless, as health benefits of breastfeeding are well demonstrated and since biological pl…

Position statementmedicine.medical_specialtyCOVID-19 VaccinesConsensusCoronavirus disease 2019 (COVID-19)BreastfeedingBreastfeedingConsensuHealth benefits03 medical and health sciences0302 clinical medicineObstetrics and gynaecology030225 pediatricsMedicalMedicineHumans030212 general & internal medicineVaccination.Societies Medicalbusiness.industryVaccinationlcsh:RJ1-570COVID-19lcsh:PediatricsBreastfeeding; COVID-19; Vaccination; COVID-19; Consensus; Female; Humans; Italy; Societies Medical; Breast Feeding; COVID-19 VaccinesSettore MED/38VaccinationBreast FeedingItalyFamily medicineCommentaryFemaleBiological plausibilitybusinessSocietiesBreast feedingHuman
researchProduct

Position Statement on Breastfeeding from the Italian Pediatric Societies

2015

The 2015 Position Statement on Breastfeeding of The Italian Pediatric Societies (SIP, SIN, SICupp, SIGENP) recognizes breastfeeding as an healthy behaviour with many short and long term benefits for both mother and infant. While protecting, promoting and supporting breastfeeding, neonatologists and pediatricians need specific knowledge, skills and a positive attitude toward breastfeeding. In Maternity Hospitals and in Neonatal Units, appropriate organizative interventions should be applied in order to facilitate the beginning of breastfeeding and the use of mother’s/human milk. The Italian Pediatric Societies indicate the desiderable goal of around 6 months exclusive breastfeeding if the in…

Position statementmedicine.medical_specialtyPsychological interventionBreastfeedingBreastfeedingMaternity hospitalsMothersGuidelines as TopicPosition statementSpecific knowledgePediatricsMedicineHumansIntensive care medicinePosition Statement Breastfeeding mother's/human milkSocieties MedicalMilk Humanbusiness.industryMaternal and child healthHuman milkInfantBreast FeedingSettore MED/38 - PEDIATRIA GENERALE E SPECIALISTICAFamily medicineCommentaryFemalePositive attitudebusinessBreast feeding
researchProduct

Applying systematic review search methods to the grey literature: a review of education and training courses on breastfeeding support for health prof…

2021

Abstract Background Currently, lactation training courses aimed at health professionals are important for informing and supporting mothers who are breastfeeding. In this review, we seek to analyze similarities and/or variations in course content, modes of delivery, costs, teaching style and learning strategies among courses. To our knowledge, a review of lactation training courses available worldwide is lacking. Thus, the aim of this review is to describe course models aimed at training health professionals in lactation support for mothers. Methods Through searching grey literature, training courses were obtained from several directories, including the Alaska Breastfeeding Coalition, Intern…

Postnatal CareCertificationLactation consultantHealth PersonnelInfants AlimentacióeducationBreastfeedingReviewCertificationTraining (civil)Personal sanitari03 medical and health sciences0302 clinical medicinePregnancy030225 pediatricsHumansLactationTrainingMedicine030212 general & internal medicineDuration (project management)Childhealth care economics and organizationsAccreditationMedical educationbusiness.industrylcsh:Public aspects of medicinelcsh:RJ1-570Obstetrics and Gynecologylcsh:Pediatricslcsh:RA1-1270Grey literatureBreast FeedingAllianceLactation coursesPediatrics Perinatology and Child HealthHealth professionalsProgramsFemalebusinessSystematic Reviews as Topic
researchProduct

The human milk microbiome changes over lactation and is shaped by maternal weight and mode of delivery

2012

Background Breast milk is recognized as the most important postpartum element in metabolic and immunologic programming of health of neonates. The factors influencing the milk microbiome and the potential impact of microbes on infant health have not yet been uncovered. Objective Our objective was to identify pre- and postnatal factors that can potentially influence the bacterial communities inhabiting human milk. Design We characterized the milk microbial community at 3 different time points by pyrosequencing and quantitative polymerase chain reaction in mothers (n = 18) who varied in BMI, weight gain, and mode of delivery. Results We found that the human milk microbiome changes over lactati…

PregnancyNutrition and Dieteticsbiologyfood and beveragesMedicine (miscellaneous)PhysiologyBreast milkbiology.organism_classificationmedicine.diseaseObesityfluids and secretionsmedicine.anatomical_structureLactationImmunologymedicinePrevotellaColostrumMicrobiomemedicine.symptomWeight gainThe American Journal of Clinical Nutrition
researchProduct

Social Vision on Wet Nurses in the [Spanish] Newspaper “La Vanguardia” (1881-1908)

2017

Históricamente ha habido situaciones y momentos en que las madres han delegado el proceso de lactancia en nodrizas. En el siglo XIX las nodrizas fueron representadas en la prensa española reproduciendo los esquemas del modelo social androcéntrico imperante. Se pretende describir y categorizar la visión de la nodriza reflejada en la prensa española mediante el análisis de contenido de las fuentes periodísticas de este período. La conclusión alcanzada han sido que la prensa refleja la importancia social de la nodriza como un elemento normalizado en la sociedad con un papel fundamental en los aspectos demográficos de la sociedad, estableciendo una visión dual en función del grupo social al que…

PremsaNodrizaPressLactancia asalariada/mercenariaPrensaWet nurseLactancia maternaLa VanguardiaBreastfeedingMercenary/waged lactationInfermersEnfermería
researchProduct

Apports nutritionnels en France en 2005 chez les enfants non allaités âgés de moins de 36 mois

2008

Resume Contexte Malgre l’interet scientifique de sa connaissance, le statut nutritionnel des enfants francais en bas âge n’a ete que peu etudie. Objectifs Evaluer les apports energetiques, macro- et micronutritionnels des enfants francais âges de un a 36 mois. Procedure experimentale Une enquete alimentaire transversale a ete realisee de janvier a mars 2005 sur un echantillon representatif des nourrissons et enfants francais en bas âge, tenant compte de l’âge des enfants, de l’activite professionnelle de la mere, de la categorie socioeconomique de la famille, mais en excluant les enfants totalement ou partiellement nourris au sein. Sujets Sept cent six enfants ont ete repartis en 11 groupes…

Preschool childFood intakemedia_common.quotation_subjectPediatrics Perinatology and Child HealthNutritional statusArtBreast feedingHumanitiesmedia_commonArchives de Pédiatrie
researchProduct

Y179C, F486L and N550H are BRCA1 variants that may be associated with breast cancer in a Sicilian family: results of a 5-year GOIM (Gruppo Oncologico…

2006

Background Over 600 different pathogenic mutations have been identified in the BRCA1 gene. Nevertheless, numerous missense mutations of unknown biological function still exist. Understanding of biological significance of these mutations should help in genetic counselling to carriers and their families. Patients and methods A total of 104 patients with breast and/or ovarian cancer whose genetic counselling answered the criteria of the American Society of Clinical Oncology (ASCO 2003), were prospectively screened for mutations in all coding exons of the BRCA1 gene by automatic direct sequencing. Results During these mutational screening procedures one case presented three mutations classified…

ProbandAdultmedicine.medical_specialtyProtein ConformationGenetic counselingGenes BRCA1Mutation MissenseBreast NeoplasmsGenetic CounselingExonBreast cancermedicineMissense mutationHumansProspective StudiesGeneSicilyScreening proceduresGerm-Line MutationGynecologyGeneticsFamily HealthOvarian Neoplasmsbusiness.industryBRCA1 ProteinGenetic VariationHematologyDNA NeoplasmExonsmedicine.diseasePedigreeOncologyFemalebusinessOvarian cancerAnnals of oncology : official journal of the European Society for Medical Oncology
researchProduct

In Vitro and in Vivo Evaluation of Water-Soluble Iminophosphorane Ruthenium(II) Compounds. A Potential Chemotherapeutic Agent for Triple Negative Bre…

2014

A series of organometallic ruthenium(II) complexes containing iminophosphorane ligands have been synthesized and characterized. Cationic compounds with chloride as counterion are soluble in water (70–100 mg/mL). Most compounds (especially highly water-soluble 2) are more cytotoxic to a number of human cancer cell lines than cisplatin. Initial mechanistic studies indicate that the cell death type for these compounds is mainly through canonical or caspase-dependent apoptosis, nondependent on p53, and that the compounds do not interact with DNA or inhibit protease cathepsin B. In vivo experiments of 2 on MDA-MB-231 xenografts in NOD.CB17-Prkdc SCID/J mice showed an impressive tumor reduction (…

Programmed cell deathStereochemistryPhosphoranesAntineoplastic AgentsTriple Negative Breast NeoplasmsMice SCIDPharmacologyIn Vitro TechniquesArticleRutheniumIn vivoCoordination ComplexesMice Inbred NODDrug DiscoverymedicineOrganometallic CompoundsCytotoxic T cellAnimalsHumansCathepsinCisplatinChemistryWaterIn vitro3. Good healthHEK293 CellsSolubilityCell cultureApoptosisMolecular MedicineFemalemedicine.drugJournal of Medicinal Chemistry
researchProduct