Search results for "BT"
showing 10 items of 1498 documents
Determination of absolute internal conversion coefficients using the SAGE spectrometer
2016
Abstract A non-reference based method to determine internal conversion coefficients using the SAGE spectrometer is carried out for transitions in the nuclei of 154 Sm, 152 Sm and 166 Yb. The Normalised-Peak-to-Gamma method is in general an efficient tool to extract internal conversion coefficients. However, in many cases the required well-known reference transitions are not available. The data analysis steps required to determine absolute internal conversion coefficients with the SAGE spectrometer are presented. In addition, several background suppression methods are introduced and an example of how ancillary detectors can be used to select specific reaction products is given. The results o…
Evolution of nuclear structure in neutron-rich odd-Zn isotopes and isomers
2017
Collinear laser spectroscopy was performed on Zn (Z=30) isotopes at ISOLDE, CERN. The study of hyperfine spectra of nuclei across the Zn isotopic chain, N=33–49, allowed the measurement of nuclear spins for the ground and isomeric states in odd-A neutron-rich nuclei up to N=50. Exactly one long-lived (&
A test of charge-parity-time invariance at the atto-electronvolt scale
2017
We developed a novel fast measurement procedure for cyclotron frequency comparisons of two individual particles in a Penning trap, which enabled us to compare the charge-to-mass ratio of the proton and the antiproton with a fractional precision of 69 parts per trillion. To date this is the most precise test of charge-parity-time invariance using baryons. Our measurements were performed at cyclotron frequencies of about 30 MHz, which means that charge-parity-time symmetry holds at the atto-electronvolt scale.
I prodotti da New Plant Breeding Techniques: criticità di inquadramento normativo tra aspetti tecnico-scientifici e valutazioni di opportunità
2020
Nell’ultimo decennio l’evoluzione in campo biotecnologico ha portato istituzioni, autorità ed esperti ad interrogarsi sulla possibilità di applicare le norme in materia di oGM anche agli alimenti risultato dell’applicazione di nuove tecniche genomiche (c.d. New Plant Breeding Techniques o NPBT) A seguito della pronuncia della Corte di giustizia del luglio 2018 e in considerazione del permanere della situazione di incertezza, il Consiglio, nel novembre 2019, ha richiesto alla Commissione europea di raccogliere dei dati e presentare una proposta concreta sullo statuto delle NPBT entro il 2021, al fine di definire linee applicative chiare in materia e che fossero il frutto di un contemperame…
Characterization of softwood and hardwood lignoboost kraft lignins with emphasis on their antioxidant activity
2014
Fractionation of softwood and hardwood LignoBoost kraft lignins, using sequential extraction with organic solvents of increasing hydrogen-bonding ability (dichloromethane, n-propanol, and methanol), was carried out. Using SEC, analytical pyrolysis, FTIR and UV/VIS spectroscopy, and chemical analytical methods, four fractions were obtained and characterized in terms of their yield, composition, functionality, lignin structural features, and antioxidant properties. In tests with free radicals (ABTS●+, DPPH●, O2●-) and the ORAC (oxygen radical absorbance capacity) assay, the high radical scavenging capacity of the lignin’s soluble fractions was demonstrated. The antioxidant activity of the fra…
Increases of intracanal and root surface temperatures during the obturation of canal using the E&Q master system and the system
2010
Objectives: The purpose of our study is to assess the increases of intracanal and root surface temperatures during the obturation of canal system using the E&Q Master System and the System B. Materials and methods: A split-tooth model was built. To measure the temperature, 6 grooves for the placement of thermocouples were made in the buccal half of the model. On the mesial side, three grooves were made at 2, 4 and 6 mm from the anatomical apex and were extended to the root surface, while on the distal side three grooves were made at 2, 4 and 6 mm up to the intracanal portion. In each of these grooves was inserted a type T thermocouple (Copper-Costantana) with a diameter of 0.076 mm. 40 cana…
Genes differentially expressed by Aspergillus carbonarius strains under ochratoxin A producing conditions
2010
Aspergillus carbonarius is an important ochratoxin A (OTA)-producing fungus that is responsible for toxin contamination of grapes and wine, coffee and cocoa. A suppression subtractive hybridization (SSH) approach was performed with two strains of A. carbonarius, antagonistic in their OTA-production ability, to identify genes whose expression is linked with the ability to produce OTA. BlastX analysis identified 109 differentially-expressed sequences putatively involved in the production of OTA, with significant similarities (Evalue < 10− 5) to sequences deposited in the NCBI non-redundant protein database. Of the 109 ESTs, 26% were involved in regulation processes, 15% corresponded to hypoth…
First Nationwide Molecular Screening Program in Spain for Patients With Advanced Breast Cancer: Results From the AGATA SOLTI-1301 Study
2021
Anàlisi de seqüències d'ADN; Subtipus PAM50; Genètica molecular Análisis de secuencias de ADN; Subtipo PAM50; Genética molecular DNA sequence analyses; PAM50 subtype; Molecular genetic Background: The SOLTI-1301 AGATA study aimed to assess the feasibility of a multi-institutional molecular screening program to better characterize the genomic landscape of advanced breast cancer (ABC) and to facilitate patient access to matched-targeted therapies in Spain. Methods: DNA sequencing of 74 cancer-related genes was performed using FFPE tumor samples in three different laboratories with three different gene panels. A multidisciplinary advisory board prospectively recommended potential targeted trea…
Detection of postoperative plasma circulating tumour DNA and lack of CDX2 expression as markers of recurrence in patients with localised colon cancer
2020
BACKGROUND: Colon cancer (CC) is a heterogeneous disease. Novel prognostic factors beyond pathological staging are required to accurately identify patients at higher risk of relapse. Integrating these new biological factors, such as plasma circulating tumour DNA (ctDNA), CDX2 staining, inflammation-associated cytokines and transcriptomic consensus molecular subtypes (CMS) classification, into a multimodal approach may improve our accuracy in determining risk of recurrence.; METHODS: One hundred and fifty patients consecutively diagnosed with localised CC were prospectively enrolled in our study. ctDNA was tracked to detect minimal residual disease by droplet digital PCR. CDX2 expression was…
Clinical utility of plasma-based digital next-generation sequencing (NGS) in patients with advance-stage lung adenocarcinomas with insufficient tumor…
2018
9101Background: Approximately 20 % of tumor biopsies from patients with advanced-stage lung adenocarcinomas yield insufficient tissue for successful molecular subtyping. In this study, we have anal...