Search results for "Base"
showing 10 items of 8362 documents
SOUTH AMERICAN COLLABORATION IN SCIENTIFIC PUBLICATIONS ON LEISHMANIASIS: BIBLIOMETRIC ANALYSIS IN SCOPUS (2000-2011)
2014
Objetivos: Evaluar la producción y la red de colaboración de investigación sobre leishmaniasis en Sudamérica. Métodos: Se realizó un estudio bibliométrico usando la base de datos SCOPUS. La unidad de análisis fueron los artículos originales de investigación publicados desde el año 2000 hasta 2011, realizados sobre leishmaniasis y que incluyeron al menos un autor sudamericano. Se obtuvieron para cada artículo: nombre de la revista, idioma, año de publicación, número de autores, instituciones, países y otras variables. Resultados: 3174 artículos fueron publicados, 2.272 de ellos eran artículos originales. Se identificaron 1.160 firmas institucionales diferentes, 58 países y 398 revistas cient…
Fuzzy Methods and Approximate Reasoning in Geographical Information Systems
2014
This issue has been dedicated to the usage of fuzzy logic in the context of Geographical Information Systems (GIS) and were receveid the following papers whose contents are described below: - in the paper of A. Hofmann, S. Hoskova-Mayerova, and V. Talhofer, the authors use a GIS tool which is useful to study the influence of geographic and climatic factors on the terrain passability of armed forces and the Integrated Rescue System. - In the first paper of S. Sessa and F. Di Martino, the authors propose the usage of the well known Extended Gustafson-Kessel clustering method, encapsulated in a GIS tool, for detecting hotspots in spatial analysis. The data consist of geo-referenced patterns co…
The Electronic Historical Latvian Dictionary Based on the Corpus of Early Written Latvian Texts
2016
The Electronic Historical Latvian Dictionary Based on the Corpus of Early Written Latvian Texts This article deals with the development of the Electronic Historical Latvian Dictionary (http://www.tezaurs.lv/lvvv) based on the Corpus of Early Written Latvian Texts (http://www.korpuss.lv/senie/). Some issues concerning the compilation and processing of the corpus data are discussed and the main sources added to the Corpus during the four-year project are described: the 16th c. Lord’s Prayers , 17th c. dictionaries, texts of oaths and laws, religious texts and so-called dedication poetry. The aim of the project is to compile a pilot electronic dictionary of 16th–17th century Latvian where all…
A physical model for the interaction between unsaturated soils and retaining structures
2020
Temporary and permanent retaining structures interact with soils that are usually in unsaturated conditions. In this work, a 1g-scale physical model is presented to investigate the interactions between retaining walls and unsaturated soils. The physical model is equipped with a water-filled hydraulic cylinder connected to a pressure-volume controller to measure the horizontal component of the later earth thrust and high capacity tensiometers to measure soil matric suction. A system of low-friction linear guideways has been installed at the base of the wall-model. The failure surface is observed through a 3 cm thick glass wall on one side of the container. A series of images are acquired dur…
Discharges of past flood events based on historical river profiles
2008
Abstract. This paper presents a case study on the estimation of peak discharges of extreme flood events during the 19th century of the Neckar River located in south-western Germany. It was carried out as part of the BMBF (German Federal Ministry of Education and Research) research project RIMAX (Risk Management of Extreme Flood Events). The discharge estimations were made for the 1824 and 1882 flood events, and are based on historical cross profiles. The 1-D model Hydrologic Engineering Centers River Analysis System (HEC-RAS) was applied with different roughness coefficients to determine these estimations. The results are compared (i) with contemporary historical calculations for the 1824 a…
An Approach to Delineate Groundwater Bodies at Risk: Seawater Intrusion in Liepāja (Latvia)
2018
Groundwater quality in coastal areas is frequently affected by seawater intrusion as a consequence of intensive water consumption. To achieve “good chemical status” of a groundwater body according to Water Framework Directive the effects of saline or other intrusions should not be observed. Groundwater pumping in former decades has caused a significant seawater intrusion into confined aquifer in Liepāja and has led to deterioration of relatively wide coastal area of the third largest city in Latvia. However, the area affected by seawater intrusion is a small part of groundwater body F1 which overall chemical status is good. Thus, no specific management measures have been applied to explore …
Microhydrological Niches in Soils: How Mucilage and EPS Alter the Biophysical Properties of the Rhizosphere and Other Biological Hotspots
2019
Plant roots and bacteria are capable of buffering erratic fluctuations of water content in their local soil environment by releasing a diverse, highly polymeric blend of substances (e.g. extracellular polymeric substances [EPS] and mucilage). Although this concept is well accepted, the physical mechanisms by which EPS and mucilage interact with the soil matrix and determine the soil water dynamics remain unclear. High-resolution X-ray computed tomography revealed that upon drying in porous media, mucilage (from maize [Zea mays L.] roots) and EPS (from intact biocrusts) form filaments and two-dimensional interconnected structures spanning across multiple pores. Unlike water, these mucilage a…
Microbiological Stability of Bio-Based Building Materials
2021
The aim of this paper was to study the microbiological stability of bio-based composite building materials, which are made using organic-rich lake sediments (further – sapropel) with lime and magnesium cement as binders and hemp shives as filler. The microbial stability properties of the obtained composite materials were investigated and compared to similar composites. Because of their high organic content, these materials are prone to biodegradation; therefore, they were coated with ALINA LIFE TM organoclay coating, which helps to extend the product life, reducing the rate of biodegradation compared to the biocides used in industry. The effect of the coating on the resistance to decay by t…
Bovine herpesvirus 4-based vector delivering the full length xCT DNA efficiently protects mice from mammary cancer metastases by targeting cancer ste…
2018
Despite marked advancements in its treatment, breast cancer is still the second leading cause of cancer death in women, due to relapses and distal metastases. Breast cancer stem cells (CSCs), are a cellular reservoir for recurrence, metastatic evolution and disease progression, making the development of novel therapeutics that target CSCs, and thereby inhibit metastases, an urgent need. We have previously demonstrated that the cystine-glutamate antiporter xCT (SLC7A11), a protein that was shown to be overexpressed in mammary CSCs and that plays a key role in the maintenance of their redox balance, self-renewal and resistance to chemotherapy, is a potential target for mammary cancer immunoth…
Prediction of Specific TCR-Peptide Binding From Large Dictionaries of TCR-Peptide Pairs
2019
Abstract The T cell repertoire is composed of T cell receptors (TCR) selected by their cognate MHC-peptides and naive TCR that do not bind known peptides. While the task of distinguishing a peptide-binding TCR from a naive TCR unlikely to bind any peptide can be performed using sequence motifs, distinguishing between TCRs binding different peptides requires more advanced methods. Such a prediction is the key for using TCR repertoires as disease-specific biomarkers. We here used large scale TCR-peptide dictionaries with state-of-the-art natural language processing (NLP) methods to produce ERGO (pEptide tcR matchinG predictiOn), a highly specific classifier to predict which TCR binds to which…